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Protein
Submitted name:

AAA ATPase protein

Gene

cobS

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLigaseImported
LigandATP-bindingImported, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AAA ATPase proteinImported
Submitted name:
AAA family ATPaseImported
Submitted name:
ATPaseImported
Submitted name:
ATPase associated with various cellular activities (AAA) family proteinImported
Submitted name:
Aerobic cobaltochelatase subunit CobSImported (EC:6.6.1.2Imported)
Submitted name:
CbbQ/NirQ/NorQ/GpvN family proteinImported
Submitted name:
Putative AAA family ATPase proteinImported
Submitted name:
Putative ATP-binding proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:cobSImported
ORF Names:AOY10_00127Imported, AXA56_24395Imported, BK292_11360Imported, C6985_26300Imported, CWM24_03135Imported, DS732_30075Imported, MS6198_A107Imported, NDM1Dok01_N0108Imported, pAPEC1990_61_90Imported, pAR060302_0101Imported, pAR060302_97Imported, pNDM102337_101Imported, pNDM10505_101Imported, WR15_23145Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid pAPEC1990_61Imported
Plasmid pAR060302Imported
Plasmid pEc78Imported
Plasmid pEc9Imported
Plasmid pIncAC2-1502318Imported
Plasmid pMS6198AImported
Plasmid pNDM-1_Dok01Imported
Plasmid pNDM-EcoGN568Imported
Plasmid pNDM102337Imported
Plasmid pNDM10505Imported
Plasmid pNDM15-1078Imported
Plasmid pYDC637Imported
Plasmid pincac2-1502318Imported
Plasmid pms6198aImported
Plasmid unnamed3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000240026 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000037564 Componenti: Unassembled WGS sequence
  • UP000184369 Componenti: Unassembled WGS sequence
  • UP000094504 Componenti: Plasmid pms6198a
  • UP000256244 Componenti: Plasmid unnamed3
  • UP000258466 Componenti: Plasmid pincac2-1502318
  • UP000231954 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini64 – 188AAA_5InterPro annotationAdd BLAST125
Domaini223 – 315CbbQ_CInterPro annotationAdd BLAST93

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011704 ATPase_dyneun-rel_AAA
IPR013615 CbbQ_C
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07728 AAA_5, 1 hit
PF08406 CbbQ_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C4NVV9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQYSQFSVS KVFGMPSIPE KVTAIGYADG SNPFIPATDT NYVFRKEFLR
60 70 80 90 100
EVLAYLKEPG GDALFVTGPT GSGKTSGITE IAGRLNWPVQ QITAHGRMEL
110 120 130 140 150
TDLIGHHALV AEKPGQPPVM KFMYGPLAVA MREGHLLLIN EVDLADPAEL
160 170 180 190 200
AGLNDVLEGR PLVIAQNGGE IIKPHPMFRV VVTGNSTGSG DASGLYQGVM
210 220 230 240 250
MQNLAAMDRY RFTKVGYADE EAELSILGRA TPKLPENVRK GMVRIANQVR
260 270 280 290 300
KLFLGENGED GQISVTMSTR TLVRWAKLSL AFRGAPNALE YALDQALLIR
310 320
AAKEEREAIL RVAKDVFGDQ WR
Length:322
Mass (Da):35,158
Last modified:July 7, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2D90DD35A46FF9D3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FJ621588 Genomic DNA Translation: ACQ78064.1
HQ023863 Genomic DNA Translation: ADM62804.1
HQ023864 Genomic DNA Translation: ADM62982.1
JF503991 Genomic DNA Translation: AEN71437.1
JF714412 Genomic DNA Translation: AEP32559.1
KJ802404 Genomic DNA Translation: AIM48145.1
KP056256 Genomic DNA Translation: AIY22943.1
CP012902 Genomic DNA Translation: ALV81644.1
CP015835 Genomic DNA Translation: AOM73177.1
KY887590 Genomic DNA Translation: ASF79842.1
KY887595 Genomic DNA Translation: ASF80679.1
CP031549 Genomic DNA Translation: AXO10397.1
CP031610 Genomic DNA Translation: AXO86364.1
AP012208 Genomic DNA Translation: BAK69601.1
LGZN01000079 Genomic DNA Translation: KNF63779.1
MOGU01000019 Genomic DNA Translation: OJM95234.1
PIOQ01000042 Genomic DNA Translation: PJX98955.1
PVOU01000043 Genomic DNA Translation: PSF19508.1

NCBI Reference Sequences

More...
RefSeqi
WP_000085160.1, NZ_QETY01000078.1
YP_002894447.1, NC_012692.1
YP_006903314.1, NC_019045.2
YP_006939914.1, NC_018994.1
YP_006952936.1, NC_019066.1
YP_006953171.1, NC_019069.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AMX16802; AMX16802; A4X18_25310
AOM73177; AOM73177; MS6198_A107
KIG83264; KIG83264; PU38_02615
KNF63779; KNF63779; WR15_23145

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
13876813
13903614
13905840
13906079
7872712

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|562.12826.peg.5207

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ621588 Genomic DNA Translation: ACQ78064.1
HQ023863 Genomic DNA Translation: ADM62804.1
HQ023864 Genomic DNA Translation: ADM62982.1
JF503991 Genomic DNA Translation: AEN71437.1
JF714412 Genomic DNA Translation: AEP32559.1
KJ802404 Genomic DNA Translation: AIM48145.1
KP056256 Genomic DNA Translation: AIY22943.1
CP012902 Genomic DNA Translation: ALV81644.1
CP015835 Genomic DNA Translation: AOM73177.1
KY887590 Genomic DNA Translation: ASF79842.1
KY887595 Genomic DNA Translation: ASF80679.1
CP031549 Genomic DNA Translation: AXO10397.1
CP031610 Genomic DNA Translation: AXO86364.1
AP012208 Genomic DNA Translation: BAK69601.1
LGZN01000079 Genomic DNA Translation: KNF63779.1
MOGU01000019 Genomic DNA Translation: OJM95234.1
PIOQ01000042 Genomic DNA Translation: PJX98955.1
PVOU01000043 Genomic DNA Translation: PSF19508.1
RefSeqiWP_000085160.1, NZ_QETY01000078.1
YP_002894447.1, NC_012692.1
YP_006903314.1, NC_019045.2
YP_006939914.1, NC_018994.1
YP_006952936.1, NC_019066.1
YP_006953171.1, NC_019069.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAMX16802; AMX16802; A4X18_25310
AOM73177; AOM73177; MS6198_A107
KIG83264; KIG83264; PU38_02615
KNF63779; KNF63779; WR15_23145
GeneIDi13876813
13903614
13905840
13906079
7872712
PATRICifig|562.12826.peg.5207

Family and domain databases

InterProiView protein in InterPro
IPR011704 ATPase_dyneun-rel_AAA
IPR013615 CbbQ_C
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF07728 AAA_5, 1 hit
PF08406 CbbQ_C, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC4NVV9_ECOLX
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C4NVV9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: December 5, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported, PlasmidImported
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