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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Tolumonas auensis (strain DSM 9187 / TA4)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Tola_0472Imported
OrganismiTolumonas auensis (strain DSM 9187 / TA4)Imported
Taxonomic identifieri595494 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeTolumonas
Proteomesi
  • UP000009073 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi595494.Tola_0472

Structurei

3D structure databases

ProteinModelPortaliC4L9X2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 91Arg_tRNA_synt_NInterPro annotationAdd BLAST89
Domaini465 – 580DALR_1InterPro annotationAdd BLAST116

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit

Sequencei

Sequence statusi: Complete.

C4L9X2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKAQIQQLLE QTVSSLKAAA LIPVELEPRI QVDNTKDKAH GDLATNLAML
60 70 80 90 100
LAKPAGKNPR ELAQLIIEHL PASTLVARAE IAGPGFINFF LDSAWLAKQI
110 120 130 140 150
EAIAASPKAE VKAAAPAQTI VLDYSAPNVA KEMAVHHIRS TVIGDAVTRT
160 170 180 190 200
MEFLGHHVIR ANHIGDWGTQ FGMLIAYLEK VQNEQASELE LSDLEAFYRE
210 220 230 240 250
AKKHYDEDEV FAERARGYVV KLQGGDEYCR AMWKKLVDIT MAQNQIIYDR
260 270 280 290 300
LNVSLSEKDV MGESLYNPML RTVVEDLQAK GLAVESEGAL VVYLDEIKGK
310 320 330 340 350
DGEAMAVIIQ KRDGGFLYAT TDIACAKYRV ETLKADRVLY FIDSRQHQHL
360 370 380 390 400
QQAWMIARKA GYVPEQVSLE HHAFGMMLGK DGKPFKTRTG GTVKLSELLD
410 420 430 440 450
EAELRAGALI AEKSADLPEA EKAKVIHAVA MGAVKYADLS KNRTTDYIFD
460 470 480 490 500
WDNMLTFEGN TAPYLQYAYT RIQSIFRRVG DEAQPGPVQI TAPAEETLAQ
510 520 530 540 550
KLLQFNDVVH NVAQKGMPHL LCTYLYELSG CFMSFYEACP INKEGVTAAE
560 570 580
KGSRLTLCQA TAKTLTLGLS LLGIETLERM
Length:580
Mass (Da):64,253
Last modified:July 7, 2009 - v1
Checksum:iE3F198CE9E246DD0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001616 Genomic DNA Translation: ACQ92101.1
RefSeqiWP_012728700.1, NC_012691.1

Genome annotation databases

EnsemblBacteriaiACQ92101; ACQ92101; Tola_0472
KEGGitau:Tola_0472

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001616 Genomic DNA Translation: ACQ92101.1
RefSeqiWP_012728700.1, NC_012691.1

3D structure databases

ProteinModelPortaliC4L9X2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi595494.Tola_0472

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACQ92101; ACQ92101; Tola_0472
KEGGitau:Tola_0472

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC4L9X2_TOLAT
AccessioniPrimary (citable) accession number: C4L9X2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: November 7, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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