UniProtKB - C4IX13 (C4IX13_SQUAC)
Protein
Sodium/potassium-transporting ATPase subunit beta
Gene
atp1b1
Organism
Squalus acanthias (Spiny dogfish)
Status
Functioni
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane.UniRule annotation
GO - Biological processi
- potassium ion transport Source: UniProtKB-KW
- sodium ion transport Source: UniProtKB-KW
Keywordsi
Biological process | Ion transport, Potassium transport, Sodium transport, Sodium/potassium transportARBA annotation, Transport |
Ligand | Potassium, Sodium |
Protein family/group databases
TCDBi | 3.A.3.1.6, the p-type atpase (p-atpase) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Sodium/potassium-transporting ATPase subunit betaUniRule annotation |
Gene namesi | Name:atp1b1Imported |
Organismi | Squalus acanthias (Spiny dogfish)Imported |
Taxonomic identifieri | 7797 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Chondrichthyes › Elasmobranchii › Squalomorphii › Squaliformes › Squalidae › Squalus |
Subcellular locationi
Other locations
- Membrane UniRule annotation
Plasma Membrane
- sodium:potassium-exchanging ATPase complex Source: InterPro
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 37 – 62 | HelicalUniRule annotationAdd BLAST | 26 |
Keywords - Cellular componenti
Cell membraneARBA annotation, MembranePTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 114 | N-linked (GlcNAc...) asparagineCombined sources | 1 | |
Disulfide bondi | 127 ↔ 150 | Combined sources | ||
Glycosylationi | 159 | N-linked (GlcNAc...) asparagineCombined sources | 1 | |
Disulfide bondi | 160 ↔ 176 | Combined sources | ||
Disulfide bondi | 215 ↔ 278 | Combined sources |
Keywords - PTMi
Disulfide bondARBA annotation, GlycoproteinARBA annotationFamily & Domainsi
Sequence similaritiesi
Keywords - Domaini
Signal-anchorARBA annotation, Transmembrane, Transmembrane helixUniRule annotationARBA annotationFamily and domain databases
Gene3Di | 2.60.40.1660, 1 hit |
InterProi | View protein in InterPro IPR000402, Na/K_ATPase_sub_beta IPR015565, Na/K_ATPase_sub_beta_chordates IPR038702, Na/K_ATPase_sub_beta_sf |
PANTHERi | PTHR11523, PTHR11523, 1 hit PTHR11523:SF10, PTHR11523:SF10, 1 hit |
Pfami | View protein in Pfam PF00287, Na_K-ATPase, 1 hit |
TIGRFAMsi | TIGR01107, Na_K_ATPase_bet, 1 hit |
PROSITEi | View protein in PROSITE PS00390, ATPASE_NA_K_BETA_1, 1 hit PS00391, ATPASE_NA_K_BETA_2, 1 hit |
i Sequence
Sequence statusi: Complete.
C4IX13-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MARGKSKETD GGWKKFLWDS EKKEFLGRTG SSWFKIFLFY LIFYGCLAGI
60 70 80 90 100
FIGTIQVLLL TLSDFEPKYQ DRVAPPGLSH APYAIKTEIS FSISNPKSYE
110 120 130 140 150
SFVKSMHKLM DLYNESSQAG NSPFEDCSDT PADYIKRGDL DDSQGQKKAC
160 170 180 190 200
RFSRMWLKNC SGLDDTTYGY AEGKPCVVAK LNRIIGFYPK PLKNTTDLPE
210 220 230 240 250
ELQANYNQYV LPLRCAAKRE EDREKIGSIE YFGLGGYAGF PLQYYPYYGK
260 270 280 290 300
RLQKKYLQPL LAIQFTNLTQ NMELRIECKV YGENIDYSEK DRFRGRFEVK
IEVKS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM999986 mRNA Translation: CAQ53919.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM999986 mRNA Translation: CAQ53919.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2ZXE | X-ray | 2.40 | B | 1-305 | [»] | |
3A3Y | X-ray | 2.80 | B | 1-305 | [»] | |
5AVQ | X-ray | 2.60 | B | 1-305 | [»] | |
5AVR | X-ray | 2.70 | B | 1-305 | [»] | |
5AVS | X-ray | 2.90 | B | 1-305 | [»] | |
5AVT | X-ray | 2.90 | B | 1-305 | [»] | |
5AVU | X-ray | 2.55 | B | 1-305 | [»] | |
5AVV | X-ray | 2.90 | B | 1-305 | [»] | |
5AVW | X-ray | 2.60 | B | 1-305 | [»] | |
5AVX | X-ray | 3.30 | B | 1-305 | [»] | |
5AVY | X-ray | 3.45 | B | 1-305 | [»] | |
5AVZ | X-ray | 3.20 | B | 1-305 | [»] | |
5AW0 | X-ray | 3.30 | B | 1-305 | [»] | |
5AW1 | X-ray | 3.35 | B | 1-305 | [»] | |
5AW2 | X-ray | 3.20 | B | 1-305 | [»] | |
5AW3 | X-ray | 3.35 | B | 1-305 | [»] | |
5AW4 | X-ray | 2.80 | B | 1-305 | [»] | |
5AW5 | X-ray | 2.90 | B | 1-305 | [»] | |
5AW6 | X-ray | 2.80 | B | 1-305 | [»] | |
5AW7 | X-ray | 2.90 | B | 1-305 | [»] | |
5AW8 | X-ray | 2.80 | B | 1-305 | [»] | |
5AW9 | X-ray | 2.80 | B | 1-305 | [»] | |
SMRi | C4IX13 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
DIPi | DIP-59760N |
IntActi | C4IX13, 2 interactors |
Protein family/group databases
TCDBi | 3.A.3.1.6, the p-type atpase (p-atpase) superfamily |
Family and domain databases
Gene3Di | 2.60.40.1660, 1 hit |
InterProi | View protein in InterPro IPR000402, Na/K_ATPase_sub_beta IPR015565, Na/K_ATPase_sub_beta_chordates IPR038702, Na/K_ATPase_sub_beta_sf |
PANTHERi | PTHR11523, PTHR11523, 1 hit PTHR11523:SF10, PTHR11523:SF10, 1 hit |
Pfami | View protein in Pfam PF00287, Na_K-ATPase, 1 hit |
TIGRFAMsi | TIGR01107, Na_K_ATPase_bet, 1 hit |
PROSITEi | View protein in PROSITE PS00390, ATPASE_NA_K_BETA_1, 1 hit PS00391, ATPASE_NA_K_BETA_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C4IX13_SQUAC | |
Accessioni | C4IX13Primary (citable) accession number: C4IX13 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 7, 2009 |
Last sequence update: | July 7, 2009 | |
Last modified: | October 7, 2020 | |
This is version 64 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |