Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 69 (05 Jun 2019)
Sequence version 1 (28 Jul 2009)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

BRAFLDRAFT_125057

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:BRAFLDRAFT_125057Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7739 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001554 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Partially assembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

SecretedSAAS annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500293523624 – 5576Sequence analysisAdd BLAST5553

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi185 ↔ 195PROSITE-ProRule annotation
Disulfide bondi203 ↔ 212PROSITE-ProRule annotation
Disulfide bondi248 ↔ 258PROSITE-ProRule annotation
Disulfide bondi266 ↔ 275PROSITE-ProRule annotation
Disulfide bondi312 ↔ 322PROSITE-ProRule annotation
Disulfide bondi330 ↔ 339PROSITE-ProRule annotation
Disulfide bondi5508 ↔ 5562PROSITE-ProRule annotation
Disulfide bondi5512 ↔ 5564PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini181 – 213EGF-likeInterPro annotationAdd BLAST33
Domaini244 – 276EGF-likeInterPro annotationAdd BLAST33
Domaini308 – 340EGF-likeInterPro annotationAdd BLAST33
Domaini364 – 587VWFDInterPro annotationAdd BLAST224
Domaini737 – 828VWFDInterPro annotationAdd BLAST92
Domaini829 – 917VWFDInterPro annotationAdd BLAST89
Domaini1169 – 1380VWFDInterPro annotationAdd BLAST212
Domaini2991 – 3064VWFCInterPro annotationAdd BLAST74
Domaini3372 – 3443VWFCInterPro annotationAdd BLAST72
Domaini4623 – 4836VWFDInterPro annotationAdd BLAST214
Domaini4945 – 5018VWFCInterPro annotationAdd BLAST74
Domaini5325 – 5396VWFCInterPro annotationAdd BLAST72
Domaini5399 – 5476VWFCInterPro annotationAdd BLAST78
Domaini5483 – 5570CTCKInterPro annotationAdd BLAST88

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni146 – 167DisorderedSequence analysisAdd BLAST22
Regioni1542 – 1579DisorderedSequence analysisAdd BLAST38
Regioni1668 – 1699DisorderedSequence analysisAdd BLAST32
Regioni1819 – 1962DisorderedSequence analysisAdd BLAST144
Regioni2082 – 2145DisorderedSequence analysisAdd BLAST64
Regioni2433 – 2457DisorderedSequence analysisAdd BLAST25
Regioni2477 – 2556DisorderedSequence analysisAdd BLAST80
Regioni2690 – 2713DisorderedSequence analysisAdd BLAST24
Regioni3762 – 3797DisorderedSequence analysisAdd BLAST36
Regioni3920 – 3944DisorderedSequence analysisAdd BLAST25
Regioni3964 – 4043DisorderedSequence analysisAdd BLAST80
Regioni4177 – 4201DisorderedSequence analysisAdd BLAST25

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1216 Eukaryota
KOG1217 Eukaryota
ENOG41100RZ LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
C3Y5K5

Database of Orthologous Groups

More...
OrthoDBi
12226at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006207 Cys_knot_C
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR036084 Ser_inhib-like_sf
IPR002919 TIL_dom
IPR014853 Unchr_dom_Cys-rich
IPR001007 VWF_dom
IPR001846 VWF_type-D
IPR025155 WxxW_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13330 Mucin2_WxxW, 11 hits
PF01826 TIL, 4 hits
PF00094 VWD, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00832 C8, 4 hits
SM00041 CT, 1 hit
SM00181 EGF, 5 hits
SM00214 VWC, 7 hits
SM00215 VWC_out, 2 hits
SM00216 VWD, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57567 SSF57567, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01225 CTCK_2, 1 hit
PS00022 EGF_1, 3 hits
PS01186 EGF_2, 2 hits
PS50026 EGF_3, 3 hits
PS01208 VWFC_1, 2 hits
PS50184 VWFC_2, 5 hits
PS51233 VWFD, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C3Y5K5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAIGRAAALS TLLIFAAVLS TEGCGVAVNK NQEASSREIH RVRREAPETI
60 70 80 90 100
VDDVKAVNED LPHEARKLLW HSEDINDRDG NKKSRTKRDL SWPSSSLGTW
110 120 130 140 150
SDLLSGLTAE AEAEPTAGDV LSQVQAEAEP SLDDLLSQAQ AQVQAEPSID
160 170 180 190 200
EFLEQSQSQS QGQSQSEFQG ISQDIQIVNG TIVYCQQDCE NGGVCTGLNV
210 220 230 240 250
CRCAPGWTGT YCTDHMCTQT CVHGSCSGPN TCLCDEGYQG ETCEQAICNP
260 270 280 290 300
VCANGGVCTA PNECQCEEGY EGDQCQTAIC HSTCENGGYC SRPDFCTCQI
310 320 330 340 350
GYAGQQCETP ICTLECQNGG VCTEPGRCSC PSSFGGPQCQ YDLYQDDGIT
360 370 380 390 400
QVQTTPAPDH SGRFCGAFGH QHYFTFDGHF YTFPGTCQYL LSGDCLQATF
410 420 430 440 450
QVFVRNDPNC TTSSLLCHRE VRVHMMGLSH DLILHQGHNY EVTKGDVTLS
460 470 480 490 500
LPNSEEGVKV EKVGDYVRVI LMPEFDGKLV RVAVYWDGVT SVYVEVDEDF
510 520 530 540 550
AGNLCGLCGN FNGNSSDEYR LRDGTASSSR ITFANSWKMT DAEEHCPNVH
560 570 580 590 600
VNTPNSCASA TQQQLQEIWG ICNVLIGNAA FAPCHAVVDP NPYLDACVTD
610 620 630 640 650
LCNCDYAVRG DCQCEALTQY SRACAHRRIV LDWRQPELCY RGCPATMVYT
660 670 680 690 700
ECASSCPRTC RNPTGDHDCD DHCVDGCSCP EGSLWDEGSL QCVVEQECPC
710 720 730 740 750
THLGMEYAPG SNYLDDCNKY YCLAGRWIGT NLECNATCSI HGDPHITTFD
760 770 780 790 800
KRYYQFAGVC QYIVAKDFVN QQFTLLADQQ PCGDDDSSSC IRSVTLIVGG
810 820 830 840 850
NTAGKIKLHQ HGVLSVGHSD VHLQLPYHNA LKGHTKGLCG TFNDKQNDDF
860 870 880 890 900
TTRSGVIVAN VAEFGNSWKV SADCEDQPVV TSDLQLGPCA INTQRAEYAR
910 920 930 940 950
QHCGLMSGGS FEACNRLLEP ATYITACEYD VCQCQDGDEC LCSAIAHYAR
960 970 980 990 1000
ECAKLGAVVN WRTEGTCVEE CPQVGQVWQE CSSACRSSCR YLSEPDSGCT
1010 1020 1030 1040 1050
EDCVAGCNCP PGLYQSESGA CVPQEECQCF YQGEVYQTQT STVLGNLICF
1060 1070 1080 1090 1100
CEDGIMNCQE RVIMSSEYNC TSGMEYFDCE GAAAGQMGKA CEETCGNIGM
1110 1120 1130 1140 1150
ECLAEQCVSG CQCPHGLVRD GSECVLPEEC RCEHNGQMYD PGQTISVDCN
1160 1170 1180 1190 1200
SCTCSQGVWS CTTKECAAQC SMFGNSHYTT FDGHSYEFEG TCKYIIAQDY
1210 1220 1230 1240 1250
CYNQTGSFRI HAEKTACNGL SGNVCARTVT VTLQQLQIHL EHGKDVHVGP
1260 1270 1280 1290 1300
IPGSEVAYTS YKFNIYRSGF FTIIKVENGI DLYWDNATRL YIKVWPNHRG
1310 1320 1330 1340 1350
RVCGMCGNFD GNQINDFNTP ELDRATTVQD FANSWKVSSS CPDVEAPLSD
1360 1370 1380 1390 1400
YCALHPHREA WARRQCNIIL SDTFSPCHYK VDPEPYYQAC VQDSCSCDSG
1410 1420 1430 1440 1450
GDCECFCTAV AAYGDMCNTQ DVHIRWRTHE LCPTQCEDYN WDPEKCEWHY
1460 1470 1480 1490 1500
DPCGTSCPAT CEDPHPSSCD LQCMEGCHPK CPNGTVLYNG KCIPPMDCPV
1510 1520 1530 1540 1550
TTTTPLPTTT AFIPTTVSTT LLPTTTESIA TTTLEVTTAS ETTPMPTTTR
1560 1570 1580 1590 1600
GEGGGKTTTA APTTEVTPTG SPSPPVQTTT EATTIQSTTT FSTTTPEVTT
1610 1620 1630 1640 1650
PCEHAEVCYW TSWINSDLPR NYRKILSALI MSGLYCDASQ IPGFFGVCYD
1660 1670 1680 1690 1700
YEIRVKCCWE ECVTPTSTEY PPTTTESTTV STTTEPTTTE STTSTVSTTT
1710 1720 1730 1740 1750
QPTTTESIVT TTPCEHVEEM CEWSDWMNKD EPSDGNPNQN ETYDNLRDIY
1760 1770 1780 1790 1800
EFCEEPMDIE CSVAGMEGTQ MSLPEGVSCD QATGLVCYAS QLPGKGQVCE
1810 1820 1830 1840 1850
DYQIRVKCCS EKCVTPVPTT TRPTTTPTTT VSTTTQPTTT ETTTVSTTQP
1860 1870 1880 1890 1900
TTTETTTVST TTQPTTTETT SSTTVMTPTG SPSPTQPPTT ESTTVSTTSQ
1910 1920 1930 1940 1950
PTTTESTTVS TTSQPTTTES TTVSTTSQPT TTESTTSTVS TTTQSTTTES
1960 1970 1980 1990 2000
TTISTTQPTT TETTTTIVST TPCEHVQEMC QWSDWMNKEY PNPNSPSQNE
2010 2020 2030 2040 2050
TYANLRDTYD FCDTPMDIQC GISGIPMNTP FESIAQEGVM CDINSGLYCD
2060 2070 2080 2090 2100
ASQISGFFGV CYDYEIRVKC CWEECVTPTT TRPTTTESTT VSTEYQPTTT
2110 2120 2130 2140 2150
ESTTVSTTTE PTTTESTTVS TEYQPTTTES TTVSTTTKPT TTESTTVSTE
2160 2170 2180 2190 2200
YQPTTTESTT VATTTKPTTT ESTTVSTEYQ PTTTESTTVA TTTKPTTTES
2210 2220 2230 2240 2250
TTVSTEYQPT TTESTTVTVA TTTKPTTTES TTVSTEYQPT TTESTTVATT
2260 2270 2280 2290 2300
TKPTTTESTT VSTTTQPTTT ETTTVFTTQP TTTESTTVST EYQPTTSEST
2310 2320 2330 2340 2350
TVSTTTKPTT TESTTVSTTI ITTTPCEHVE EMCEWSDWMN KDEPSGGNPN
2360 2370 2380 2390 2400
QNETYDNLRD TYEFCEAPMD IECSVAGMEG TQMSLPEGVS CDQATGLVCY
2410 2420 2430 2440 2450
ASQLPGKGQV CEDYQIRVKC CSEKCVTPVP TTTRPTTTPT TTVSTTTQPT
2460 2470 2480 2490 2500
TTETTTVSTT TQPTTTEATT SITTEGTTSI ATPTGSPSPH QTTTISTTPI
2510 2520 2530 2540 2550
TTSTHSTTQP PTTTAYRPTT TKMTTTQPTT TRTETTHPTT TEEYTTPPVP
2560 2570 2580 2590 2600
TTTEMQTTQP TTTMQTTQPT TTKLETTPTS CGYVCNWTDW MNSYNPSTDM
2610 2620 2630 2640 2650
EMNDVETLEN LHSRFSFCET PMGIECRLAE NPSLDFIDHH QNGVTCEVDS
2660 2670 2680 2690 2700
GLYCNSSLTN MRACMDYEVR FQCCHVPDSC KTTTTMTTGP TTTTGPTTTV
2710 2720 2730 2740 2750
TTEKPPPTTA TTTVTTEKPT TTIATTTMTT EKLTTAPTTT VSTTTEGTTT
2760 2770 2780 2790 2800
VETTTEYCQE TCVWSEWMNS DYPGXGVQDN HHTNYNNLYN NPANYHTDNN
2810 2820 2830 2840 2850
SFYNSPAHHC RIHHRFYKNP AHYHRDNFKY NSYDSNWFSI TNPTTHYRIH
2860 2870 2880 2890 2900
HCFHDNPAHH YRIHHCFHDS PVNHPNVLWV TCEVDSGLYC NSSLTNMRAC
2910 2920 2930 2940 2950
MDYEVRFQCC HVPDSCKTTT TMTTEVPTTT TVTTKRPTTT INTESTTVSM
2960 2970 2980 2990 3000
TTQPTTTEST TVSTTTQPTT TESTTVSTTA LPTTTAFLPP NGCEDANGMP
3010 3020 3030 3040 3050
LAIGDTWIPY NDSCQECTCT GHKKTECYPR ACPTYRPPKC GVCESQRVVE
3060 3070 3080 3090 3100
GSDSCCPEYE CVCDLNRADC PEVVIPQCEY QYQYVHHTNP GECVPEYECR
3110 3120 3130 3140 3150
CNSSKCPAAP QCEPPKVLDM LEGECCLEYE CVCDACPTAP TPYCPPGEGY
3160 3170 3180 3190 3200
VLVSSEDICS CVTHSCECRN DTCAQQPECD DNKDLVTTET GCCPHYNCTC
3210 3220 3230 3240 3250
NTCPTHGPVI NCDYAEGYVL VSSQDDCGCV TESCECREDS CSPEPECPDN
3260 3270 3280 3290 3300
KHVVTVETGC CPHYNCSCNS CPPSPTPGSD CPYGEMPGYV IHETVDDCGC
3310 3320 3330 3340 3350
VNSSCTCDRS RCPAPPTCDD NKNLVALYTP CCQNYTCECK ECPVDDTSCG
3360 3370 3380 3390 3400
IGETQTTIID DCCRHTNCTP EPVCVYQNTT HQPGTSWTDA NDNCIQCQCL
3410 3420 3430 3440 3450
EEIDPATGFH RVSCSDESSQ CEVNCPACHT YQERSGECCG ECVKTSCCVM
3460 3470 3480 3490 3500
DDDETLVEHP VSLQMPAYLC DLNRADCPEV VIPQCEYQYQ YVHHTNPGEC
3510 3520 3530 3540 3550
VPEYECRCNS SQCPAAPQCE PPKVMDMSEG ECCLEYECVC DACPTASTPY
3560 3570 3580 3590 3600
CPPGEGYVLV SSEDICGCVT QSCQCRKDTC AQQPECDDNK HLITTETDCC
3610 3620 3630 3640 3650
PHYNCTCDTC PPRPVVDCNY AEGYVLVSSQ DDCGCVTESC ECREDSCSPE
3660 3670 3680 3690 3700
PECPDNKHVV TMETGCCPHY NCSCNTCPPS PTPGSDCPYG EVTCEVDSGL
3710 3720 3730 3740 3750
YCDASLTNVG ACMDYEVRFQ CCHVPDTCKT TTTVTTEVPT TTTTVTTERP
3760 3770 3780 3790 3800
LTTITTESTT VSTTTQPTTT ESTTISTTTQ PTTTESTTVS TTTQPTTTES
3810 3820 3830 3840 3850
TTVSTTIIST TPCEHVEEMC EWSDWMNKDE PSGGNPNQNE TYDNLRDIYE
3860 3870 3880 3890 3900
FCEAPMDIEC SVAGMEGTQM SLPEGVSCDQ ATGLVCYASQ LPGKGQVCED
3910 3920 3930 3940 3950
YQIRVKCCSE KCVTPVPTTT RPTTTPTTTV STTTQPTTTE TTTVSTTTQP
3960 3970 3980 3990 4000
TTTEATTSIT TEGTTSIATP TGSPSPHQTT TISTTPITTS THSTTQPPTT
4010 4020 4030 4040 4050
TAYRPTTTKM TTTQPTTTRT ETTHPTTTEE YTTPPVPTTT EMQTTQPTTT
4060 4070 4080 4090 4100
MQTTQPTTTK LETTPTSCGY VCNWTDWMNS YNPSTDMEMN DVETLENLHS
4110 4120 4130 4140 4150
RFSFCETPMG IECRLAENPS LDFIDHHQNG VTCEVDSGLY CNSSLTNMRA
4160 4170 4180 4190 4200
CMDYEVRFQC CHVPDSCKTT TTMTTGPTTT TGPTTTVTTE KPPPTTATTT
4210 4220 4230 4240 4250
VTTEKPTTTI ATTTMTTEKL TTAPTTTVST TTEGTTTVET TTEYCQETCV
4260 4270 4280 4290 4300
WSEWMNSDYP GVGVPNDNET FAHLRESSLE FCEEPDDIEC RLDMTPNVDF
4310 4320 4330 4340 4350
NRAKQSGVEC DVSSGLLCLS KLQPSLLHDN SEDNHHTNYN NLYNNPANYH
4360 4370 4380 4390 4400
TDNNSFYNSP AHHCRIHHRF YKNPAHYHRD NFKYNSYDSN WFSITNPTTH
4410 4420 4430 4440 4450
YRIHHCFHDN PAHHYRIHHC FHDSPVNHPN VLWVTCEVDS GLYCNSSLTN
4460 4470 4480 4490 4500
MRACMDYEVR FQCCHVPDSC KTTTTMTTEV PTTTTVTTKR PTTTINTEST
4510 4520 4530 4540 4550
TVSMTTQPTT TESTTVSTTT QPTTTESTTV STTALPTTTA FLPPSTTECP
4560 4570 4580 4590 4600
DVCIDGSGLT RQVGDTWFEA GDQCQRALYL CRPCGVISIN RKVCDVVEPP
4610 4620 4630 4640 4650
SCANGLQPID VGVCCPEYQC PCECKGYGDP HYFSFDGEYF YFQGEGEFIL
4660 4670 4680 4690 4700
ARDTHVPHDF EVRGFNVQCT VAPITTCTKE IKVIYKGHTI ELKTGHQVLV
4710 4720 4730 4740 4750
NGTSWTPPFK LDGCKVTTMG FPLKLEIQSL DVTVVYDFLS SGFYISVPPT
4760 4770 4780 4790 4800
MYAGKTEGLC GPCNNNKTDD CQDREGTIMN DYNNCSCDWK VDNPDSPSNS
4810 4820 4830 4840 4850
CIPEPKPTAT PSTPCDQSPC DIITDPEGPF GACHDVVDYE FFLQSCQYDR
4860 4870 4880 4890 4900
GACYSECQAL GAYAYVCQRM GVCVDWRGKG NNCSFECEAG LVYKACSCVK
4910 4920 4930 4940 4950
TCENMDVFNA SQCALAYMET EGCFCPDDMV LHETSEQCIE GDTCNGCEDA
4960 4970 4980 4990 5000
NGMPLAIGDT WIPYNDSCQE CTCTGHKKIE CYPRACPTYQ PPKCGVCESQ
5010 5020 5030 5040 5050
RVVEGSDSCC PEYECVCDLN RADCPEVVIP QCEYQYQYVH HTNPGECVPE
5060 5070 5080 5090 5100
YECRCNSSQC PAAPQCEPPK VMDMSEGECC LEYECVCDAC PTASTPYCPP
5110 5120 5130 5140 5150
GEGYVLVSSE DICGCVTQSC QCRKDTCAQQ PECDDNKHLI TTETDCCPHY
5160 5170 5180 5190 5200
NCTCDTCPPR PVVDCNYAEG YVLVSSQDDC GCVTESCECR EDSCSPEPEC
5210 5220 5230 5240 5250
PDNKHVVTME TGCCPHYNCS CNTCPPSPTP GSDCPYGEMP GYVIHETVDD
5260 5270 5280 5290 5300
CGCVNSSCTC DRSRCPAPPT CDDNKNLVAL YTPCCQNYTC ECKECPVDDT
5310 5320 5330 5340 5350
SCGIGETQTT VIDDCCRHTN CTPEPVCVYQ NTTHQPGTSW TDANDNCIRC
5360 5370 5380 5390 5400
QCLEEIDPAT GFHRVSCSDE SSQCEVNCPA CHTYQERSGE CCGECVKTSC
5410 5420 5430 5440 5450
CVMDDDETLV EHPAGSNWTS PGDSCSRCHC LEAGEHGQVV EYCSTLLCPE
5460 5470 5480 5490 5500
PPTCSSDEVM KNTSSADGCC TIYECVPPGQ ASCSLFTKQD YLRVDDCVSL
5510 5520 5530 5540 5550
QPVNVTWCEG RCGSSSMYEG VDLKHTCECC HEVSMSEVSV PMECEGTTTS
5560 5570
SMSYAYRQIT ACDCDTTECE VPTAQP
Length:5,576
Mass (Da):609,789
Last modified:July 28, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAE26F0E7433B4612
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GG666487 Genomic DNA Translation: EEN64252.1

NCBI Reference Sequences

More...
RefSeqi
XP_002608242.1, XM_002608196.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7243369

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bfo:BRAFLDRAFT_125057

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG666487 Genomic DNA Translation: EEN64252.1
RefSeqiXP_002608242.1, XM_002608196.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7243369
KEGGibfo:BRAFLDRAFT_125057

Phylogenomic databases

eggNOGiKOG1216 Eukaryota
KOG1217 Eukaryota
ENOG41100RZ LUCA
InParanoidiC3Y5K5
OrthoDBi12226at2759

Family and domain databases

InterProiView protein in InterPro
IPR006207 Cys_knot_C
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR036084 Ser_inhib-like_sf
IPR002919 TIL_dom
IPR014853 Unchr_dom_Cys-rich
IPR001007 VWF_dom
IPR001846 VWF_type-D
IPR025155 WxxW_domain
PfamiView protein in Pfam
PF13330 Mucin2_WxxW, 11 hits
PF01826 TIL, 4 hits
PF00094 VWD, 4 hits
SMARTiView protein in SMART
SM00832 C8, 4 hits
SM00041 CT, 1 hit
SM00181 EGF, 5 hits
SM00214 VWC, 7 hits
SM00215 VWC_out, 2 hits
SM00216 VWD, 4 hits
SUPFAMiSSF57567 SSF57567, 4 hits
PROSITEiView protein in PROSITE
PS01225 CTCK_2, 1 hit
PS00022 EGF_1, 3 hits
PS01186 EGF_2, 2 hits
PS50026 EGF_3, 3 hits
PS01208 VWFC_1, 2 hits
PS50184 VWFC_2, 5 hits
PS51233 VWFD, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC3Y5K5_BRAFL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C3Y5K5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: June 5, 2019
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again