Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 67 (02 Jun 2021)
Sequence version 1 (16 Jun 2009)
Previous versions | rss
Add a publicationFeedback
Protein

Sodium channel protein

Gene

para

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.

UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel, Sodium channelUniRule annotationARBA annotation, Voltage-gated channelUniRule annotation
Biological processIon transport, Sodium transport, Transport
LigandSodium

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.1.10.16, the voltage-gated ion channel (vic) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium channel proteinUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:paraImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7159 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008820 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
VectorBase:AAEL023266

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei144 – 171HelicalUniRule annotationAdd BLAST28
Transmembranei215 – 237HelicalUniRule annotationAdd BLAST23
Transmembranei249 – 267HelicalUniRule annotationAdd BLAST19
Transmembranei273 – 296HelicalUniRule annotationAdd BLAST24
Transmembranei404 – 426HelicalUniRule annotationAdd BLAST23
Transmembranei803 – 826HelicalUniRule annotationAdd BLAST24
Transmembranei847 – 864HelicalUniRule annotationAdd BLAST18
Transmembranei876 – 900HelicalUniRule annotationAdd BLAST25
Transmembranei931 – 953HelicalUniRule annotationAdd BLAST23
Transmembranei973 – 990HelicalUniRule annotationAdd BLAST18
Transmembranei1011 – 1032HelicalUniRule annotationAdd BLAST22
Transmembranei1321 – 1339HelicalUniRule annotationAdd BLAST19
Transmembranei1360 – 1382HelicalUniRule annotationAdd BLAST23
Transmembranei1388 – 1414HelicalUniRule annotationAdd BLAST27
Transmembranei1435 – 1466HelicalUniRule annotationAdd BLAST32
Transmembranei1553 – 1579HelicalUniRule annotationAdd BLAST27
Transmembranei1642 – 1660HelicalUniRule annotationAdd BLAST19
Transmembranei1672 – 1691HelicalUniRule annotationAdd BLAST20
Transmembranei1703 – 1722HelicalUniRule annotationAdd BLAST20
Transmembranei1766 – 1789HelicalUniRule annotationAdd BLAST24
Transmembranei1859 – 1879HelicalUniRule annotationAdd BLAST21

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

Disulfide bondARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1896 – 1931EF-handInterPro annotationAdd BLAST36

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni36 – 81DisorderedSequence analysisAdd BLAST46
Regioni1203 – 1259DisorderedSequence analysisAdd BLAST57
Regioni2019 – 2115DisorderedSequence analysisAdd BLAST97

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili430 – 465Sequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi36 – 65Basic and acidic residuesSequence analysisAdd BLAST30
Compositional biasi1208 – 1244Basic and acidic residuesSequence analysisAdd BLAST37
Compositional biasi1245 – 1259Acidic residuesSequence analysisAdd BLAST15
Compositional biasi2069 – 2084Polar residuesSequence analysisAdd BLAST16
Compositional biasi2100 – 2114Polar residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sodium channel (TC 1.A.1.10) family. [View classification]UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotationARBA annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13433, Na_channel_gate, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002048, EF_hand_dom
IPR005821, Ion_trans_dom
IPR001696, Na_channel_asu
IPR044564, Na_chnl_inactivation_gate
IPR010526, Na_trans_assoc
IPR024583, Na_trans_cytopl
IPR043203, VGCC_Ca_Na
IPR027359, Volt_channel_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10037, PTHR10037, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00520, Ion_trans, 4 hits
PF06512, Na_trans_assoc, 1 hit
PF11933, Na_trans_cytopl, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00170, NACHANNEL

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50222, EF_HAND_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

C3RTM3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTEDSDSISE EERSLFRPFT RESLAAIERR IADAEAKQRE LEKKRAEGET
60 70 80 90 100
GFGRKKKKKE IRYDDEDEDE GPQPDSTLEQ GVPIPVRMQG SFPPELASTP
110 120 130 140 150
LEDIDSYYAN QRTFVVVSKG KDIFRFSATN ALYVLDPFNP IRRVAIYILV
160 170 180 190 200
HPLFSFFIIT TILTNCILMI MPSTPTVEST EVIFTGIYTF ESAVKVMARG
210 220 230 240 250
FILQPFTYLR DAWNWLDFVV IALAYVTMGI DLGNLAALRT FRVLRALKTV
260 270 280 290 300
AIVPGLKTIV GAVIESVKNL RDVIILTMFS LSVFALMGLQ IYMGVLTQKC
310 320 330 340 350
IREFPMDGSW GNLSDENWER FNNNDSNWYF SETGDTPLCG NSSGAGQCEE
360 370 380 390 400
GYICLQGYGD NPNYGYTSFD TFGWAFLSAF RLMTQDYWEN LYQLVLRSAG
410 420 430 440 450
PWHMLFFIVI IFLGSFYLVN LILAIVAMSY DELQKRAEEE EAAEEEALRE
460 470 480 490 500
AEEAAAAKAA KLEAQAAAAA AAANPEIAKS PSDFSCHSYE LFVNQEKGND
510 520 530 540 550
DNNKEKMSIR SEGLESVSEI TRTTAPTATA AGTAKARKVS AGVAAFQKAS
560 570 580 590 600
LSLPGSPFNL RRGSRGSHQF TIRNGRGRFV GVPGSDRKPL VLSTYLDAQE
610 620 630 640 650
HLPYADDSNA VTPMSEENGA IIVPVYYANL GSRHSSYTSH QSRISYTSHG
660 670 680 690 700
DLLGGMTKES RLRNRSARNT NHSIVPPPNM SGPNMSYVDS NHKGQRDFDM
710 720 730 740 750
SQDCTDEAGK IKHNDNPFIE PSQTQTVVDM KDVMVLNDII EQAAGRHSRA
760 770 780 790 800
SDHGVSVYYF PTEDDDEDGP TFKDKALEFT MRMIDVFCVW DCCWVWLKFQ
810 820 830 840 850
EWVAFIVFDP FVELFITLCI VVNTLFMALD HHDMDPDMER ALKSGNYFFT
860 870 880 890 900
ATFAIEATMK LIAMSPKYYF QEGWNIFDFI IVALSLLELG LEGVQGLSVL
910 920 930 940 950
RSFRLLRVFK LAKSWPTLNL LISIMGRTMG ALGNLTFVLC IIIFIFAVMG
960 970 980 990 1000
MQLFGKNYID NVDRFPDKDL PRWNFTDFMH SFMIVFRVLC GEWIESMWDC
1010 1020 1030 1040 1050
MLVGDVSCIP FFLATVVIGN LVGLNLFLAL LLSNFGSSSL SAPTADNETN
1060 1070 1080 1090 1100
KIAEAFNRIS RFSNWIKSNI ANALKFVKNK LTSQIASVQP AGEQHNHLSW
1110 1120 1130 1140 1150
IWNEGKGVCP CISAEHGENE LELTPDDILA DGLLKKGVKE HNQLEVAIGD
1160 1170 1180 1190 1200
GMEFTIHGDL KNKGKKNKQL MNNSKVIGNS ISNHQDNKLE HELNHRGMSL
1210 1220 1230 1240 1250
QDDDTASIKS YGSHKNRPFK DESHKGSAET MEGEEKRDVS KEDLGIDEEL
1260 1270 1280 1290 1300
DDECDGEEGP LDGELIIHAD EDEVIEDSPA DCCPDNCYKK FPVLAGDDDA
1310 1320 1330 1340 1350
PFWQGWANLR LKTFQLIENK YFETAVITMI LLSSLALALE DVHLPHRPIL
1360 1370 1380 1390 1400
QDVLYYMDRI FTVIFFLEML IKWLALGFRV YFTNAWCWLD FIIVMVSLIN
1410 1420 1430 1440 1450
FVASLCGAGG IQAFKTMRTL RALRPLRAMS RMQGMRVVVN ALVQAIPSIF
1460 1470 1480 1490 1500
NVLLVCLIFW LIFAIMGVQL FAGKYFKCVD KNKTTLSHEI IPDVNACVAE
1510 1520 1530 1540 1550
NYTWENSPMN FDHVGKAYLC LFQVATFKGW IQIMNDAIDS REVGKQPIRE
1560 1570 1580 1590 1600
TNIYMYLYFV FFIIFGSFFT LNLFIGVIID NFNEQKKKAG GSLEMFMTED
1610 1620 1630 1640 1650
QKKYYNAMKK MGSKKPLKAI PRPRWRPQAI VFEIVTNKKF DMIIMLFIGF
1660 1670 1680 1690 1700
NMLTMTLDHY KQTDTFSAVL DYLNMIFICI FSSECLMKIF ALRYHYFIEP
1710 1720 1730 1740 1750
WNLFDFVVVI LSILGLVLSD LIEKYFVSPT LLRVVRVAKV GRVLRLVKGA
1760 1770 1780 1790 1800
KGIRTLLFAL AMSLPALFNI CLLLFLVMFI FAIFGMSFFM HVKYKSGLDD
1810 1820 1830 1840 1850
VYNFKTFGQS MILLFQMSTS AGWDGVLDGI INEDECLPPD NDKGYPGNCG
1860 1870 1880 1890 1900
SATIGITYLL AYLVISFLIV INMYIAVILE NYSQATEDVQ EGLTDDDYDM
1910 1920 1930 1940 1950
YYEIWQQFDP DGTQYIRYDQ LSDFLDVLEP PLQIHKPNKY KIISMDIPIC
1960 1970 1980 1990 2000
RGDMMFCVDI LDALTKDFFA RKGNPIEETA ELGEVQARPD EVGYEPVSST
2010 2020 2030 2040 2050
LWRQREEYCA RVIQHAWRKH KERQAGGGGG DDTDADACDN DDGDDGGGGA
2060 2070 2080 2090 2100
GDGGSAGGGG VTSPGVGSGS IVGGGTTPGS GGGGSQANLG IVVEHNLSPK
2110 2120 2130 2140
ESPDGNNDPQ GRQTAVLVES DGFVTKNGHR VVIHSRSPSI TSRSADV
Length:2,147
Mass (Da):240,913
Last modified:June 16, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i29AD701F8A9CA916
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C3RTM1C3RTM1_AEDAE
Sodium channel protein
para
2,140Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C3RTM2C3RTM2_AEDAE
Sodium channel protein
para
2,140Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EU399181 mRNA Translation: ACB37024.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU399181 mRNA Translation: ACB37024.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

TCDBi1.A.1.10.16, the voltage-gated ion channel (vic) superfamily

Organism-specific databases

VEuPathDBiVectorBase:AAEL023266

Family and domain databases

CDDicd13433, Na_channel_gate, 1 hit
Gene3Di1.20.120.350, 4 hits
InterProiView protein in InterPro
IPR002048, EF_hand_dom
IPR005821, Ion_trans_dom
IPR001696, Na_channel_asu
IPR044564, Na_chnl_inactivation_gate
IPR010526, Na_trans_assoc
IPR024583, Na_trans_cytopl
IPR043203, VGCC_Ca_Na
IPR027359, Volt_channel_dom_sf
PANTHERiPTHR10037, PTHR10037, 1 hit
PfamiView protein in Pfam
PF00520, Ion_trans, 4 hits
PF06512, Na_trans_assoc, 1 hit
PF11933, Na_trans_cytopl, 1 hit
PRINTSiPR00170, NACHANNEL
PROSITEiView protein in PROSITE
PS50222, EF_HAND_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC3RTM3_AEDAE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C3RTM3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: June 2, 2021
This is version 67 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again