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  1. 1
    "Identification of a pancreatic adenocarcinoma upregulated factor (PAUF)."
    Koh S.S., Lee Y., Song S.Y., Kim S.-A.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).
  2. 2
    "Identification of a human ortholog of the mouse Dcpp gene locus, encoding a novel member of the CSP-1/Dcpp salivary protein family."
    Mullins J.J., Mullins L.J., Dunbar D.R., Brammar W.J., Gross K.W., Morley S.D.
    Physiol. Genomics 28:129-140(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: Bioinformatic analysis identified a putative human CSP-1/Dcpp ortholog HRPE773 expressed predominantly in human salivary tissue that shows 31% amino acid identity and 45% amino acid similarity to the mouse Dcpp query sequence.Imported.
    Source: GeneRIF:124220.

    This publication is cited by 1 and mapped to 3 other entries.

  3. 3
    "Pancreatic adenocarcinoma up-regulated factor (PAUF), a novel up-regulated secretory protein in pancreatic ductal adenocarcinoma."
    Kim S.A., Lee Y., Jung D.E., Park K.H., Park J.Y., Gang J., Jeon S.B., Park E.C., Kim Y.G., Lee B., Liu Q., Zeng W., Yeramilli S., Lee S., Koh S.S., Song S.Y.
    Cancer Sci. 100:828-836(2009) [PubMed] [Europe PMC] [Abstract]
    Annotation: pancreatic adenocarcinoma up-regulated factor was secreted into the culture medium of pancreatic adenocarcinoma up-regulated factor-overexpressing Chinese hamster ovary cells had an apparent molecular mass of approximately 25 kDa and was N-glycosylatedImported.
    Source: GeneRIF:124220.

    This publication is mapped to 3 other entries.

  4. 4
    "PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression."
    Lee Y., Kim S.J., Park H.D., Park E.H., Huang S.M., Jeon S.B., Kim J.M., Lim D.S., Koh S.S.
    Oncogene 29:56-67(2010) [PubMed] [Europe PMC] [Abstract]
    Annotation: Findings indicate that PAUF enhances the metastatic potential of pancreatic cancer cells at least in part by upregulating CXCR4 expression.Imported.
    Source: GeneRIF:124220.

    This publication is mapped to 7 other entries.

  5. 5
    "Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation."
    Park H.D., Lee Y., Oh Y.K., Jung J.G., Park Y.W., Myung K., Kim K.H., Koh S.S., Lim D.S.
    Oncogene 30:201-211(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: PAUF is a mammalian lectin normally found in plant lectins. PAUF induces extracellular signal-regulated kinase phosphorylation and activates the IKK-b-mediated TPL2/MEK/ERK signaling pathway through TLR2.Imported.
    Source: GeneRIF:124220, IntAct:C3PTT6.

    This publication is mapped to 24 other entries.

  6. 6
    "Human common salivary protein 1 (CSP-1) promotes binding of Streptococcus mutans to experimental salivary pellicle and glucans formed on hydroxyapatite surface."
    Ambatipudi K.S., Hagen F.K., Delahunty C.M., Han X., Shafi R., Hryhorenko J., Gregoire S., Marquis R.E., Melvin J.E., Koo H., Yates J.R.
    J. Proteome Res. 9:6605-6614(2010) [PubMed] [Europe PMC] [Abstract]
    Annotation: Data demonstrate that the host salivary protein CSP-1 (HRPE773 GenBank AAQ89380.1) binds to S. mutans cells and may influence the initial colonization of this pathogenic bacterium onto the tooth surface.Imported.
    Source: GeneRIF:124220.

    This publication is mapped to 3 other entries.

  7. 7
    "Crystal structures of human secretory proteins ZG16p and ZG16b reveal a Jacalin-related beta-prism fold."
    Kanagawa M., Satoh T., Ikeda A., Nakano Y., Yagi H., Kato K., Kojima-Aikawa K., Yamaguchi Y.
    Biochem. Biophys. Res. Commun. 404:201-205(2011) [PubMed] [Europe PMC] [Abstract]
    Annotation: the sugar-binding site and the adjacent basic patch of ZG16p and ZG16b cooperatively form a functional glycosaminoglycan-binding site.Imported.
    Source: GeneRIF:124220.

    This publication is cited by 1 and mapped to 2 other entries.

  8. 8
    "Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the expression of beta-catenin, leading to a rapid proliferation of pancreatic cells."
    Cho I.R., Koh S.S., Min H.J., Kim S.J., Lee Y., Park E.H., Ratakorn S., Jhun B.H., Oh S., Johnston R.N., Chung Y.H.
    Exp. Mol. Med. 43:82-90(2011) [PubMed] [Europe PMC] [Abstract]
    Annotation: PAUF can up-regulate and stabilize beta-catenin via a novel pattern of phosphorylation thereby contributing to the rapid proliferation of pancreatic cancer cells.Imported.
    Source: GeneRIF:124220.

    This publication is mapped to 4 other entries.

  9. 9
    "PAUF promotes adhesiveness of pancreatic cancer cells by modulating focal adhesion kinase."
    Lee Y.S., Kim S.J., Min H.J., Jo J.Y., Park E.H., Koh S.S.
    Exp. Mol. Med. 43:291-297(2011) [PubMed] [Europe PMC] [Abstract]
    Annotation: PAUF-mediated FAK activation plays an important role in pancreatic cancer progression.Imported.
    Source: GeneRIF:124220.

    This publication is mapped to 3 other entries.

  10. 10
    "SIRT1 inhibits proliferation of pancreatic cancer cells expressing pancreatic adenocarcinoma up-regulated factor (PAUF), a novel oncogene, by suppression of beta-catenin."
    Cho I.R., Koh S.S., Malilas W., Srisuttee R., Moon J., Choi Y.W., Horio Y., Oh S., Chung Y.H.
    Biochem. Biophys. Res. Commun. 423:270-275(2012) [PubMed] [Europe PMC] [Abstract]
    Annotation: activation of SIRT1 inhibited the proliferation of pancreatic cancer -PAUF cells by down-regulation of cyclin-D1 a target molecule of beta-catenin.Imported.
    Source: GeneRIF:124220.

    This publication is mapped to 15 other entries.

  11. 11
    "Pancreatic adenocarcinoma upregulated factor, a novel endothelial activator, promotes angiogenesis and vascular permeability."
    Kim S.J., Lee Y., Kim N.Y., Hwang Y., Hwang B., Min J.K., Koh S.S.
    Oncogene 32:3638-3647(2013) [PubMed] [Europe PMC] [Abstract]
    Annotation: new possibilities for PAUF's role in the pathogenesis of angiogenesis-dependent diseasesImported.
    Source: GeneRIF:124220.

    This publication is mapped to 3 other entries.

  12. 12
    "A new class of carriers that transport selective cargo from the trans Golgi network to the cell surface."
    Wakana Y., van Galen J., Meissner F., Scarpa M., Polishchuk R.S., Mann M., Malhotra V.
    EMBO J. 31:3976-3990(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:C3PTT6.

    This publication is mapped to 8 other entries.

  13. 13
    "Silencing of pancreatic adenocarcinoma upregulated factor by RNA interference inhibits the malignant phenotypes of human colorectal cancer cells."
    Liu P.F., Wu Y.Y., Hu Y., Wang L., He S.B., Zhu Y.B., Zhu X.G.
    Oncol. Rep. 30:213-220(2013) [PubMed] [Europe PMC] [Abstract]
    Annotation: PAUF-siRNA inhibited the proliferation of colorectal cancer cells promoted their apoptosis and induced G0/G1 cell cycle arrest. At the same time PAUF-siRNA inhibited the invasion adhesion and migration of the tumor cells.Imported.
    Source: GeneRIF:124220.

    This publication is mapped to 3 other entries.

  14. 14
    "Genetic variation in microRNA-binding site and prognosis of patients with colorectal cancer."
    Kim J.G., Chae Y.S., Lee S.J., Kang B.W., Park J.Y., Lee E.J., Jeon H.S., Park J.S., Choi G.S.
    J. Cancer Res. Clin. Oncol. 141:35-41(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: PAUF rs12373A>C polymorphisms are associated with colorectal cancer.Imported.
    Source: GeneRIF:124220.

    This publication is mapped to 7 other entries.

  15. 15
    Category: Interaction.
    Source: IntAct:C3PTT6.

    This publication is mapped to 4117 other entries.

  16. 16
    "Pancreatic adenocarcinoma upregulated factor (PAUF) confers resistance to pancreatic cancer cells against oncolytic parvovirus H-1 infection through IFNA receptor-mediated signaling."
    Kaowinn S., Cho I.R., Moon J., Jun S.W., Kim C.S., Kang H.Y., Kim M., Koh S.S., Chung Y.H.
    Biochem. Biophys. Res. Commun. 459:313-318(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: constitutive suppression of PAUF sensitized Bxpc3 pancreatic cancer cells to oncolytic parvovirus H-1 infectionImported.
    Source: GeneRIF:124220.

    This publication is mapped to 3 other entries.

  17. 17
    "Pancreatic adenocarcinoma upregulated factor serves as adjuvant by activating dendritic cells through stimulation of TLR4."
    Kang T.H., Kim Y.S., Kim S., Yang B., Lee J.J., Lee H.J., Lee J., Jung I.D., Han H.D., Lee S.H., Koh S.S., Wu T.C., Park Y.M.
    Oncotarget 6:27751-27762(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: PAUF mediated dendritic cell activation and immune stimulation are dependent on TLR4Imported.
    Source: GeneRIF:124220.

    This publication is mapped to 3 other entries.

  18. 18
    "Silencing pancreatic adenocarcinoma upregulated factor (PAUF) increases the sensitivity of pancreatic cancer cells to gemcitabine."
    Gao C.C., Xu X.L., Li F., Gong B.G., Liu S., Cui Y.Q., Sun H.C., Xu P.Y., Zheng Y.M., Jiang H.
    Tumour Biol. 37:7555-7564(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: High PAUF expression is associated with resistance to gemcitabine in pancreatic cancer.Imported.
    Source: GeneRIF:124220.

    This publication is mapped to 3 other entries.

  19. 19
    "Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer."
    Song J., Lee J., Kim J., Jo S., Kim Y.J., Baek J.E., Kwon E.S., Lee K.P., Yang S., Kwon K.S., Kim D.U., Kang T.H., Park Y.Y., Chang S., Cho H.J., Kim S.C., Koh S.S., Kim S.
    Oncotarget 7:51840-51853(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: we conclude that the PAUF is a powerful and multifunctional promoter of tumor growth through increase and functional activation of myeloid-derived suppressor cellsImported.
    Source: GeneRIF:124220.

    This publication is mapped to 3 other entries.

  20. 20
    "Pancreatic adenocarcinoma up-regulated factor has oncogenic functions in oral squamous cell carcinoma."
    Sasahira T., Kurihara M., Nishiguchi Y., Nakashima C., Kirita T., Kuniyasu H.
    Histopathology 70:539-548(2017) [PubMed] [Europe PMC] [Abstract]
    Annotation: Our results suggest that PAUF has tumour-promoting functions in oral squamous cell carcinomaImported.
    Source: GeneRIF:124220.

    This publication is mapped to 3 other entries.

  21. 21
    "DCPP1 is the mouse ortholog of human PAUF that possesses functional analogy in pancreatic cancer."
    Song H., Song J., Kim Y.J., Jeong H.H., Min H.J., Koh S.S.
    Biochem. Biophys. Res. Commun. 493:1498-1503(2017) [PubMed] [Europe PMC] [Abstract]
    Annotation: Mouse DCPP1 is a multifunctional promoter of tumor growth through functional activation of pancreatic cancer cells suggesting it to be an ortholog of human PAUF.Imported.
    Source: GeneRIF:124220.

    This publication is mapped to 8 other entries.

1 to 21 of 21  Show

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