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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Vibrio cholerae serotype O1 (strain M66-2)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:VCM66_1554
OrganismiVibrio cholerae serotype O1 (strain M66-2)
Taxonomic identifieri579112 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000001217 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001885371 – 362Ribosomal RNA large subunit methyltransferase FAdd BLAST362

Proteomic databases

PRIDEiC3LMU1

Structurei

3D structure databases

ProteinModelPortaliC3LMU1
SMRiC3LMU1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218605
KOiK06970
OMAiTEFHQGH

Family and domain databases

HAMAPiMF_01848 23SrRNA_methyltr_F, 1 hit
InterProiView protein in InterPro
IPR016909 rRNA_lsu_MeTfrase_F
IPR010286 rRNA_lsu_MeTfrase_F-like
IPR029063 SAM-dependent_MTases
PANTHERiPTHR13393 PTHR13393, 1 hit
PfamiView protein in Pfam
PF05971 Methyltransf_10, 1 hit
PIRSFiPIRSF029038 Mtase_YbiN_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit

Sequencei

Sequence statusi: Complete.

C3LMU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTPLKPKHG QKTNRKPKAN KPVVKKQQTK QPPTHKVQGE EVAAVKSGLH
60 70 80 90 100
PRNRHRGQYD FPALIKVVPE LQSHVMKNPK GQWTINFADP ISVKLLNKAL
110 120 130 140 150
LVLHYGVTYW DIPEGFLCPP IPGRADYIHR VADLLLKGNP QLNHSQVRAL
160 170 180 190 200
DIGVGANCIY PIVGVTEYGW SWVGSDVDPV SIQQASLIVQ SNSKLQGHIE
210 220 230 240 250
CRLQKNSQHI FNGIIGANER YTVTTCNPPF HASLADAQQG TQRKLTNLQA
260 270 280 290 300
NQRKKGRLAT PTLSHSRLNF GGQKAELWCP GGEAAFIGKM AVESQQFAQQ
310 320 330 340 350
VLWFSTLISK GDNVRGMKKQ LEKLGAQSIH VIEMAQGQKI SRFIAWSFQN
360
AEQRKLWWQA KC
Length:362
Mass (Da):40,486
Last modified:June 16, 2009 - v1
Checksum:iEFA809AEE03CDB52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001233 Genomic DNA Translation: ACP05867.1
RefSeqiWP_001095834.1, NC_012578.1

Genome annotation databases

EnsemblBacteriaiACP05867; ACP05867; VCM66_1554
KEGGivcm:VCM66_1554

Similar proteinsi

Entry informationi

Entry nameiRLMF_VIBCM
AccessioniPrimary (citable) accession number: C3LMU1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: June 7, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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