UniProtKB - C3L1U2 (ARLY_CLOB6)
Protein
Argininosuccinate lyase
Gene
argH
Organism
Clostridium botulinum (strain 657 / Type Ba4)
Status
Functioni
Catalytic activityi
- EC:4.3.2.1UniRule annotation
: L-arginine biosynthesis Pathwayi
This protein is involved in step 3 of the subpathway that synthesizes L-arginine from L-ornithine and carbamoyl phosphate.UniRule annotationProteins known to be involved in the 3 steps of the subpathway in this organism are:
- no protein annotated in this organism
- Argininosuccinate synthase (argG)
- Argininosuccinate lyase (argH)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-arginine from L-ornithine and carbamoyl phosphate, the pathway L-arginine biosynthesis and in Amino-acid biosynthesis.
GO - Molecular functioni
- argininosuccinate lyase activity Source: UniProtKB-UniRule
GO - Biological processi
- arginine biosynthetic process via ornithine Source: InterPro
Keywordsi
Molecular function | Lyase |
Biological process | Amino-acid biosynthesis, Arginine biosynthesis |
Enzyme and pathway databases
UniPathwayi | UPA00068;UER00114 |
Names & Taxonomyi
Protein namesi | Recommended name: Argininosuccinate lyaseUniRule annotation (EC:4.3.2.1UniRule annotation)Short name: ASALUniRule annotation Alternative name(s): ArginosuccinaseUniRule annotation |
Gene namesi | Name:argHUniRule annotation Ordered Locus Names:CLJ_B2900 |
Organismi | Clostridium botulinum (strain 657 / Type Ba4) |
Taxonomic identifieri | 515621 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm UniRule annotation
Other locations
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000201692 | 1 – 440 | Argininosuccinate lyaseAdd BLAST | 440 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
HOGENOMi | CLU_027272_2_3_9 |
OMAi | MPGRTHL |
Family and domain databases
CDDi | cd01359, Argininosuccinate_lyase, 1 hit |
Gene3Di | 1.10.275.10, 1 hit |
HAMAPi | MF_00006, Arg_succ_lyase, 1 hit |
InterProi | View protein in InterPro IPR029419, Arg_succ_lyase_C IPR009049, Argininosuccinate_lyase IPR024083, Fumarase/histidase_N IPR020557, Fumarate_lyase_CS IPR000362, Fumarate_lyase_fam IPR022761, Fumarate_lyase_N IPR008948, L-Aspartase-like |
PANTHERi | PTHR43814, PTHR43814, 1 hit |
Pfami | View protein in Pfam PF14698, ASL_C2, 1 hit PF00206, Lyase_1, 1 hit |
PRINTSi | PR00149, FUMRATELYASE |
SUPFAMi | SSF48557, SSF48557, 1 hit |
TIGRFAMsi | TIGR00838, argH, 1 hit |
PROSITEi | View protein in PROSITE PS00163, FUMARATE_LYASES, 1 hit |
i Sequence
Sequence statusi: Complete.
C3L1U2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKLWGGRFKE EESKLMEDFN SSLSFDKKLY YEDIKGSIAH VKMLANQNII
60 70 80 90 100
KEEEKEKILL GLEEILKEID EGILKIEGDY EDIHSFVEIN LINKIGNVGK
110 120 130 140 150
KLHTGRSRND QVALDMKLYA KKSTEEVIEC LKELMDSLIK VGNENNYIMP
160 170 180 190 200
GYTHLQRAQV VTFRYHLLAY FEMFKRDEKR LENALEFLNE SPLGSGALAG
210 220 230 240 250
STYNIDREYT AKLLGFRKPV DNFLDGVSDR DYIIELISKF SIIMMHLSRL
260 270 280 290 300
SEELILWSSS EFRFIQIGDA YSTGSSIMPQ KKNPDGAELI RGKIGRVYGD
310 320 330 340 350
LISILTVMKS LPLAYNKDMQ EDKEPFFDAK DTVISCLKVM EGIISTLKVN
360 370 380 390 400
KENLMKSVKK GFLNATEAAD YLVNKGMAFR DAHKVIGEVV IYCEDKNSAI
410 420 430 440
EDLSLEELKQ FSDLFCEDIY EFIDYKNSIN KGIKKEMGYF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001083 Genomic DNA Translation: ACQ54208.1 |
RefSeqi | WP_003361359.1, NC_012658.1 |
Genome annotation databases
EnsemblBacteriai | ACQ54208; ACQ54208; CLJ_B2900 |
KEGGi | cbi:CLJ_B2900 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001083 Genomic DNA Translation: ACQ54208.1 |
RefSeqi | WP_003361359.1, NC_012658.1 |
3D structure databases
SMRi | C3L1U2 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | ACQ54208; ACQ54208; CLJ_B2900 |
KEGGi | cbi:CLJ_B2900 |
Phylogenomic databases
HOGENOMi | CLU_027272_2_3_9 |
OMAi | MPGRTHL |
Enzyme and pathway databases
UniPathwayi | UPA00068;UER00114 |
Family and domain databases
CDDi | cd01359, Argininosuccinate_lyase, 1 hit |
Gene3Di | 1.10.275.10, 1 hit |
HAMAPi | MF_00006, Arg_succ_lyase, 1 hit |
InterProi | View protein in InterPro IPR029419, Arg_succ_lyase_C IPR009049, Argininosuccinate_lyase IPR024083, Fumarase/histidase_N IPR020557, Fumarate_lyase_CS IPR000362, Fumarate_lyase_fam IPR022761, Fumarate_lyase_N IPR008948, L-Aspartase-like |
PANTHERi | PTHR43814, PTHR43814, 1 hit |
Pfami | View protein in Pfam PF14698, ASL_C2, 1 hit PF00206, Lyase_1, 1 hit |
PRINTSi | PR00149, FUMRATELYASE |
SUPFAMi | SSF48557, SSF48557, 1 hit |
TIGRFAMsi | TIGR00838, argH, 1 hit |
PROSITEi | View protein in PROSITE PS00163, FUMARATE_LYASES, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ARLY_CLOB6 | |
Accessioni | C3L1U2Primary (citable) accession number: C3L1U2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 22, 2009 |
Last sequence update: | June 16, 2009 | |
Last modified: | December 2, 2020 | |
This is version 61 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families