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UniProtKB - C3K275 (DNAK_PSEFS)
Protein
Chaperone protein DnaK
Gene
dnaK
Organism
Pseudomonas fluorescens (strain SBW25)
Status
Functioni
Acts as a chaperone.
UniRule annotationGO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- ATP hydrolysis activity Source: InterPro
- unfolded protein binding Source: InterPro
GO - Biological processi
- protein folding Source: InterPro
Keywordsi
Molecular function | Chaperone |
Biological process | Stress response |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Chaperone protein DnaKUniRule annotationAlternative name(s): HSP70UniRule annotation Heat shock 70 kDa proteinUniRule annotation Heat shock protein 70UniRule annotation |
Gene namesi | Name:dnaKUniRule annotation Ordered Locus Names:PFLU_5269 |
Organismi | Pseudomonas fluorescens (strain SBW25) |
Taxonomic identifieri | 216595 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000205194 | 1 – 638 | Chaperone protein DnaKAdd BLAST | 638 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 199 | Phosphothreonine; by autocatalysisUniRule annotation | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
PRIDEi | C3K275 |
Expressioni
Inductioni
By stress conditions e.g. heat shock.UniRule annotation
Interactioni
GO - Molecular functioni
- unfolded protein binding Source: InterPro
Protein-protein interaction databases
STRINGi | 294.SRM1_00809 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 602 – 638 | DisorderedSequence analysisAdd BLAST | 37 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 617 – 638 | Basic and acidic residuesSequence analysisAdd BLAST | 22 |
Sequence similaritiesi
Belongs to the heat shock protein 70 family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0443, Bacteria |
HOGENOMi | CLU_005965_2_1_6 |
OMAi | ISIKRHM |
OrthoDBi | 161217at2 |
Family and domain databases
Gene3Di | 1.20.1270.10, 1 hit 2.60.34.10, 1 hit |
HAMAPi | MF_00332, DnaK, 1 hit |
InterProi | View protein in InterPro IPR043129, ATPase_NBD IPR012725, Chaperone_DnaK IPR018181, Heat_shock_70_CS IPR029048, HSP70_C_sf IPR029047, HSP70_peptide-bd_sf IPR013126, Hsp_70_fam |
PANTHERi | PTHR19375, PTHR19375, 1 hit |
Pfami | View protein in Pfam PF00012, HSP70, 1 hit |
SUPFAMi | SSF100920, SSF100920, 1 hit SSF100934, SSF100934, 1 hit SSF53067, SSF53067, 2 hits |
TIGRFAMsi | TIGR02350, prok_dnaK, 1 hit |
PROSITEi | View protein in PROSITE PS00297, HSP70_1, 1 hit PS00329, HSP70_2, 1 hit PS01036, HSP70_3, 1 hit |
i Sequence
Sequence statusi: Complete.
C3K275-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKIIGIDLG TTNSCVSVME NGKAKVIENA EGARTTPSII AYANDGEILV
60 70 80 90 100
GQSAKRQAVT NPHNTLYAVK RLIGRKFDEE VVQKDIKMVP YKIAKADNGD
110 120 130 140 150
AWVEVNGNKM SAPQISAEVL KKMKKTAEDY LGETVTEAVI TVPAYFNDSQ
160 170 180 190 200
RQATKDAGRI AGLDVKRIIN EPTAAALAYG MDKAKGDHTV IVYDLGGGTF
210 220 230 240 250
DVSVIEIAEV DGEHQFEVLA TNGDTFLGGE DFDIRLIDYL VDEFKKESGM
260 270 280 290 300
NLKGDPLAMQ RLKEAAEKAK IELSSSMSTD VNLPYITADA TGPKHLNVKI
310 320 330 340 350
SRAKLEALVE DLVQRTIEPC RIALKDAGID VGSINDVILV GGQTRMPLVQ
360 370 380 390 400
QKVTEFFGKE ARKDVNPDEA VAMGAAIQGA VLAGDVKDVL LLDVSPLTLG
410 420 430 440 450
IETMGGVMTA LIEKNTTIPT KKSQVFSTAD DNQGAVTIHV LQGERKQAAQ
460 470 480 490 500
NKSLGKFDLA EIPPAPRGVP QIEVTFDIDA NGILHVGAKD KATGKEQKIT
510 520 530 540 550
IKANSGLSDE EIQQMIRDAE ANADADAKFA ELAGARNQGD ALVHSTRKMV
560 570 580 590 600
ADAGDKVTAE EKAAIEAAVV ALEAAVKGDD KAAIEAKIEE LSKVSAPVAQ
610 620 630
KMYAEQGQPA DGAAQQAEPE AKHDDVVDAE FEEVKDQK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM181176 Genomic DNA Translation: CAY52373.1 |
RefSeqi | WP_015885931.1, NC_012660.1 |
Genome annotation databases
EnsemblBacteriai | CAY52373; CAY52373; PFLU_5269 |
KEGGi | pfs:PFLU_5269 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM181176 Genomic DNA Translation: CAY52373.1 |
RefSeqi | WP_015885931.1, NC_012660.1 |
3D structure databases
SMRi | C3K275 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 294.SRM1_00809 |
Proteomic databases
PRIDEi | C3K275 |
Genome annotation databases
EnsemblBacteriai | CAY52373; CAY52373; PFLU_5269 |
KEGGi | pfs:PFLU_5269 |
Phylogenomic databases
eggNOGi | COG0443, Bacteria |
HOGENOMi | CLU_005965_2_1_6 |
OMAi | ISIKRHM |
OrthoDBi | 161217at2 |
Family and domain databases
Gene3Di | 1.20.1270.10, 1 hit 2.60.34.10, 1 hit |
HAMAPi | MF_00332, DnaK, 1 hit |
InterProi | View protein in InterPro IPR043129, ATPase_NBD IPR012725, Chaperone_DnaK IPR018181, Heat_shock_70_CS IPR029048, HSP70_C_sf IPR029047, HSP70_peptide-bd_sf IPR013126, Hsp_70_fam |
PANTHERi | PTHR19375, PTHR19375, 1 hit |
Pfami | View protein in Pfam PF00012, HSP70, 1 hit |
SUPFAMi | SSF100920, SSF100920, 1 hit SSF100934, SSF100934, 1 hit SSF53067, SSF53067, 2 hits |
TIGRFAMsi | TIGR02350, prok_dnaK, 1 hit |
PROSITEi | View protein in PROSITE PS00297, HSP70_1, 1 hit PS00329, HSP70_2, 1 hit PS01036, HSP70_3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | DNAK_PSEFS | |
Accessioni | C3K275Primary (citable) accession number: C3K275 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 22, 2009 |
Last sequence update: | June 16, 2009 | |
Last modified: | February 23, 2022 | |
This is version 86 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families