UniProtKB - C3JZS5 (TRPF_PSEFS)
Protein
N-(5'-phosphoribosyl)anthranilate isomerase
Gene
trpF
Organism
Pseudomonas fluorescens (strain SBW25)
Status
Functioni
Catalytic activityi
- N-(5-phospho-β-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphateUniRule annotationEC:5.3.1.24UniRule annotation
: L-tryptophan biosynthesis Pathwayi
This protein is involved in step 3 of the subpathway that synthesizes L-tryptophan from chorismate.UniRule annotationProteins known to be involved in the 5 steps of the subpathway in this organism are:
- Anthranilate synthase component 1 (trpE)
- Anthranilate phosphoribosyltransferase (trpD)
- N-(5'-phosphoribosyl)anthranilate isomerase (trpF)
- Indole-3-glycerol phosphate synthase (trpC)
- Tryptophan synthase alpha chain (trpA), Tryptophan synthase beta chain (trpB)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-tryptophan from chorismate, the pathway L-tryptophan biosynthesis and in Amino-acid biosynthesis.
GO - Molecular functioni
- phosphoribosylanthranilate isomerase activity Source: UniProtKB-UniRule
GO - Biological processi
- tryptophan biosynthetic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | Isomerase |
Biological process | Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis |
Enzyme and pathway databases
BioCyci | PFLU216595:G1G1K-6414-MONOMER |
UniPathwayi | UPA00035;UER00042 |
Names & Taxonomyi
Protein namesi | Recommended name: N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)Short name: PRAIUniRule annotation |
Gene namesi | Name:trpFUniRule annotation Ordered Locus Names:PFLU_4188 |
Organismi | Pseudomonas fluorescens (strain SBW25) |
Taxonomic identifieri | 216595 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000203213 | 1 – 210 | N-(5'-phosphoribosyl)anthranilate isomeraseAdd BLAST | 210 |
Proteomic databases
PRIDEi | C3JZS5 |
Family & Domainsi
Sequence similaritiesi
Belongs to the TrpF family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0135, Bacteria |
HOGENOMi | CLU_076364_2_0_6 |
OMAi | FYAKSPR |
OrthoDBi | 1854712at2 |
Family and domain databases
CDDi | cd00405, PRAI, 1 hit |
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_00135, PRAI, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR001240, PRAI IPR011060, RibuloseP-bd_barrel |
Pfami | View protein in Pfam PF00697, PRAI, 1 hit |
SUPFAMi | SSF51366, SSF51366, 1 hit |
i Sequence
Sequence statusi: Complete.
C3JZS5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSAVRSKICG ITRIEDALAA VEAGADAIGL VFYAKSPRSV NVLQARAIIA
60 70 80 90 100
ALPPFVTTVG LFVNASRCEL NETLDAVPLD MLQFHGDETP DECESYQRPY
110 120 130 140 150
IKALRVKSGD DIAAACAAYS GARGILLDTY VEGVPGGTGE AFDWSLIPPG
160 170 180 190 200
LSKPIILAGG LTPTNVGAAI EQVQPYAVDV SGGVEQGKGI KDHSKIRAFM
210
QAVRNSSGAM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM181176 Genomic DNA Translation: CAY50704.1 |
RefSeqi | WP_015884969.1, NC_012660.1 |
Genome annotation databases
EnsemblBacteriai | CAY50704; CAY50704; PFLU_4188 |
GeneIDi | 58732524 |
KEGGi | pfs:PFLU_4188 |
PATRICi | fig|216595.4.peg.4332 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM181176 Genomic DNA Translation: CAY50704.1 |
RefSeqi | WP_015884969.1, NC_012660.1 |
3D structure databases
SMRi | C3JZS5 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 216595.PFLU_4188 |
Proteomic databases
PRIDEi | C3JZS5 |
Genome annotation databases
EnsemblBacteriai | CAY50704; CAY50704; PFLU_4188 |
GeneIDi | 58732524 |
KEGGi | pfs:PFLU_4188 |
PATRICi | fig|216595.4.peg.4332 |
Phylogenomic databases
eggNOGi | COG0135, Bacteria |
HOGENOMi | CLU_076364_2_0_6 |
OMAi | FYAKSPR |
OrthoDBi | 1854712at2 |
Enzyme and pathway databases
UniPathwayi | UPA00035;UER00042 |
BioCyci | PFLU216595:G1G1K-6414-MONOMER |
Family and domain databases
CDDi | cd00405, PRAI, 1 hit |
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_00135, PRAI, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR001240, PRAI IPR011060, RibuloseP-bd_barrel |
Pfami | View protein in Pfam PF00697, PRAI, 1 hit |
SUPFAMi | SSF51366, SSF51366, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TRPF_PSEFS | |
Accessioni | C3JZS5Primary (citable) accession number: C3JZS5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 22, 2009 |
Last sequence update: | June 16, 2009 | |
Last modified: | April 7, 2021 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families