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UniProtKB - C1JCT2 (POLFS_SINV3)

Entry version 28 (18 Sep 2019)
Sequence version 2 (22 Nov 2017)
Previous versions | rss
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Protein

Polyprotein-FSD

Gene
N/A
Organism
Solenopsis invicta virus 3 (SINV-3)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Capsid protein VP1: Assembles with VP1-FSD and VP2 to form an icosahedral capsid. VP1 is about 5 time more abundant than VP1-FSD in the virion.1 Publication
Capsid protein VP1-FSD: Assembles with VP1 and VP2 to form an icosahedral capsid. VP1 is about 5 time more abundant than VP1-FSD in the virion.1 Publication
Capsid protein VP2: Assembles with VP1 and VP1-FSD to form an icosahedral capsid.1 Publication
RNA-directed RNA polymerase: Replicates genomic and antigenomic RNA.PROSITE-ProRule annotationBy similarity

Miscellaneous

Capsid protein VP1: A sgRNA is also expressed which encloses the VP1 capsid protein and probably a leader protein.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei1258For 3C-like protease activityPROSITE-ProRule annotation1 Publication1
Active sitei1295For 3C-like protease activityPROSITE-ProRule annotation1 Publication1
Active sitei1381For 3C-like protease activityPROSITE-ProRule annotation1 Publication1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi396 – 403ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicase, Hydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymerase, Thiol protease, Transferase
Biological processViral RNA replication
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Polyprotein-FSD1 Publication
Cleaved into the following 5 chains:
Helicase1 Publication (EC:3.6.4.13Curated)
3C-like protease1 Publication (EC:3.4.22.-Curated)
Short name:
3CL-PRO
RNA-directed RNA polymerasePROSITE-ProRule annotation (EC:2.7.7.48PROSITE-ProRule annotation)
Capsid protein VP1-FSD1 Publication
Capsid protein VP21 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSolenopsis invicta virus 3 (SINV-3)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri631345 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiViruses › Riboviria › Invictavirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiSolenopsis invicta (Red imported fire ant) (Solenopsis wagneri) [TaxID: 13686]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000207613 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Capsid protein VP1-FSD :
  • Virion 1 Publication
Capsid protein VP2 :
  • Virion 1 Publication

GO - Cellular componenti

  • virion Source: UniProtKB-SubCell
Complete GO annotation on QuickGO ...

Keywords - Cellular componenti

Virion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004424451 – 3390Polyprotein-FSDAdd BLAST3390
ChainiPRO_00004424461 – ?Helicase
ChainiPRO_0000442447? – ?14323C-like protease
ChainiPRO_0000442448?1433 – 2345RNA-directed RNA polymeraseAdd BLAST913
ChainiPRO_00004424492346 – 3016Capsid protein VP1-FSDAdd BLAST671
ChainiPRO_00004424503017 – 3390Capsid protein VP2Add BLAST374

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2346N-acetylmethionine; by host1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Capsid protein VP1-FSD: N-acetylated.1 Publication
Polyprotein-FSD: Proteolytic cleavages of the polyprotein yield mature proteins.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei2345 – 2346Cleavage1 Publication2
Sitei3016 – 3017Cleavage1 Publication2

Keywords - PTMi

Acetylation

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		C1JCT2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini369 – 543SF3 helicasePROSITE-ProRule annotationAdd BLAST175
Domaini1206 – 1423Peptidase C3PROSITE-ProRule annotationAdd BLAST218
Domaini1914 – 2042RdRp catalyticPROSITE-ProRule annotationAdd BLAST129

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1176 – 1179Poly-ArgSequence analysis4
Compositional biasi3038 – 3092Gln-richPROSITE-ProRule annotationAdd BLAST55
Compositional biasi3122 – 3155Asn-richPROSITE-ProRule annotationAdd BLAST34

Phylogenomic databases

Database of Orthologous Groups

More...OrthoDBi		2102at10239

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.120.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000605 Helicase_SF3_ssDNA/RNA_vir
IPR014759 Helicase_SF3_ssRNA_vir
IPR027417 P-loop_NTPase
IPR009003 Peptidase_S1_PA
IPR001205 RNA-dir_pol_C
IPR007094 RNA-dir_pol_PSvirus
IPR029053 Viral_coat

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00680 RdRP_1, 1 hit
PF00910 RNA_helicase, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50494 SSF50494, 1 hit
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51874 PCV_3C_PRO, 1 hit
PS50507 RDRP_SSRNA_POS, 1 hit
PS51218 SF3_HELICASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by ribosomal frameshifting. AlignAdd to basket
Isoform Polyprotein-FSD (identifier: C1JCT2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSEKTQTFVQ NETHVLDMTS DFKSDLSLEK VTSSVEQTDD LVSKIINNND 
        60         70         80         90        100
LDIKDLSFLR NLLLSTLQYL GIAKFVAINI TLSILSILML LINSCAKFTR 
       110        120        130        140        150
IVNLSSHILN IITTLGLYFQ VSSMEIEEIT QTFENEFGTY DDDKILSHYI 
       160        170        180        190        200
KICNLPNRKD VYEYISLNDL KYKIKLPDIS FYELKNDILS KNKNLHLWIF 
       210        220        230        240        250
QKFTDEFLAM WFGVQPYRIS NLREMLVISR QGFIPKDLFN EIRKLCNMGV 
       260        270        280        290        300
SVIISFIQSK LFDEPFKKRD CTQALKDASV ISSPFDTLWN LISKQVCDNS 
       310        320        330        340        350
AEERFTQTIL DFTSEFDNFL GIPNYKFAKN QKLVNTISKS LDACAKFIRD 
       360        370        380        390        400
CPKDKQTEIF PLQGLHTATV KRRNEILTNV MPKFARQEPF VVLFQGPGGI 
       410        420        430        440        450
GKTHLVQQLA TKCVNSFYQD HEDDYIEISP DDKYWPPLSG QRVAFFDEAG 
       460        470        480        490        500
NLNDLTEDLL FRNIKSICSP AYFNCAAADI EHKISPCPFE LVFATVNTDL 
       510        520        530        540        550
DTLQSKISST FGQASVFPIW RRCIVVECSW NEKELGPFNY KNPSGHRSDY 
       560        570        580        590        600
SHITMNYMSY DDKTQKLALE KEINFDTLFD MIRLRFRKKQ QEHDTKISIL 
       610        620        630        640        650
NNEIQRQSNS KQHFSVCLYG EPGQGKTYNL NKLITTFANA TNLKIGSEEK 
       660        670        680        690        700
PSIHIFDDYI KDENDENCSK FMDIYNNKLP NNSVIFSATN VYPKTHFFPT 
       710        720        730        740        750
FFLTNLIYAF IQPFKQVGLY RRLGFDGYTD IPNSSVNAPI FVQNFKFYER 
       760        770        780        790        800
KQHICYFLSL EFLKNIICYI FFFLYFPLKF IKKIDLIEIK DVNKYVYDRY 
       810        820        830        840        850
INFLSLSKQI EIVEYPPNLE NVEFDFRFNM NKFHRVSFNN PFELDKYIHF 
       860        870        880        890        900
NKNSYENLLH FDWKMYLSPR VKHRLALSYE KFFITISEVN KEIIIEELKR 
       910        920        930        940        950
YVLLFKQFNI DPNMEINLGE YGSFYYINGK IHLMTINIES NVSEIPVFTD 
       960        970        980        990       1000
GDYVYISEHK IPVIDLFDNI NINSKYNLSF DQSIALNSFK TGDSFYSNAK 
      1010       1020       1030       1040       1050
VRKSLSKFVL LNYQTKFKLY LKEAKDKVKN FIETPIGHLL SILLTIFVIC 
      1060       1070       1080       1090       1100
YASFKIYSKF SNFFSKDQAI EDQRKGEKKI KKITNYDSDG VQPQRKGEKK 
      1110       1120       1130       1140       1150
IKKVTNYDSD GVQPQSNVKV EEEIKLVFDP TGQKLLFGND FTSELETLVE 
      1160       1170       1180       1190       1200
LEKDDEEFTK SKIDNKSMAG LRREVRRRRY ARSKKAQIEK QEVLTLPDVN 
      1210       1220       1230       1240       1250
GFEGGKPYFQ IAEEKARKNL CQIYMIANNE NCIASKFSDH IVCYGLFVFK 
      1260       1270       1280       1290       1300
KRLASVGHIV EALKCAPGYN LYAGCDQFNG KLYKMNLVRN YRKRELSVWD 
      1310       1320       1330       1340       1350
VDCPNDFVDL TSFFIPKEEL YDAENCNTVL GRFGMNKREV YLYGNCEFIQ 
      1360       1370       1380       1390       1400
EFFKVDNKGA QEFGYIDWAT VDITLTTGGD CGLPYYICER KKFHNKIMGL 
      1410       1420       1430       1440       1450
HFAGNNVNHK TIGMSALIYK EDLVVWKGAE RQSKCKFCDV KDIIIAQPDI 
      1460       1470       1480       1490       1500
PKEKYKGYNH EIVWNSLHES SPTTLNEELE HYLNIFPKFT GTIIKHSGDK 
      1510       1520       1530       1540       1550
FYGSVKHSHT QFISKFKTEL TVTNGWKLST AGDCQFESNH ISPNTEVMYR 
      1560       1570       1580       1590       1600
VVDVQFNSIF KAFKSQPYIK NFRLIANVYE KDGKQRVTIL TIIPVSDFNV 
      1610       1620       1630       1640       1650
KQQTVRQALV PLHLNEDEEV YVTEDVSDIF KTAIKRKQRG ILPDVPYETV 
      1660       1670       1680       1690       1700
ENETVEILGI THRNMTPEPA QMYKPTPFYK LALKFNLDHK LPVNFNMKDC 
      1710       1720       1730       1740       1750
PQEQKDMMVL DRLGQPNPRI TQSLKWAHKD YSPDYELRKY VKEQYMCNIM 
      1760       1770       1780       1790       1800
EYYAGCNLLT EEQILKGYGP NHRLYGALGG MEIDSSIGWT MKELYRVTKK 
      1810       1820       1830       1840       1850
SDVINLDSNG NYSFLNNEAA QYTQELLKIS MEQAHNGQRY YTAFNELMKM 
      1860       1870       1880       1890       1900
EKLKPSKNFI PRTFTAQDLN GVLMERWILG EFTARALAWD ENCAVGCNPY 
      1910       1920       1930       1940       1950
ATFHKFATKF FKFKNFFSCD YKNFDRTIPK CVFEDFRDML IQANPHMKNE 
      1960       1970       1980       1990       2000
IYACFQTIID RIQVSGNSIL LVHGGMPSGC VPTAPLNSKV NDIMIYTAYV 
      2010       2020       2030       2040       2050
NILRRADRGD ITSYRYYRDL VCRLFYGDDV IIAVDDSIAD IFNCQTLSEE 
      2060       2070       2080       2090       2100
MKILFGMNMT DGSKSDIIPK FETIETLSFI SRFFRPLKHQ ENFIVGALKK 
      2110       2120       2130       2140       2150
ISIQTHFYYA TDDTPEHFGQ VFKTIQEEAA LWEEEYFNKI QSYIQEIIRK 
      2160       2170       2180       2190       2200
FPEISKFFNF ESYKSIQKRY IMNGWNEFVK LEKLDLNLNK KKSSKVTGIH 
      2210       2220       2230       2240       2250
SKQYSKFLKF LSRIENEKAA LEGNFNKESV NTWYFKMSKA MHLNEIFQKG 
      2260       2270       2280       2290       2300
LISKPLAEFY FNEGQKMWDC NITFRRSKDD LPFTFSGSGT TKACAREQAA 
      2310       2320       2330       2340       2350
EEALVLFSQE DEIVRQINDI QSDCKFCKKM IRYKKLLSGV SIQRQMNVSK 
      2360       2370       2380       2390       2400
ITENHVPSAG MMATDPSVAP DSGIATNTQT PSISRVLNPI ARALDNPAGT 
      2410       2420       2430       2440       2450
GAPFDKHTYV YNVFTRWPEM STVVNKSLAA GAEVFKISLD PNKLPKRILQ 
      2460       2470       2480       2490       2500
YIQFHKTIIP QIEVQILIGG AAGTVGWLKV GWVPDASTAK KYSLDDLQLV 
      2510       2520       2530       2540       2550
ASETINLNST ITMSMIINDS RRNGMFRLTK SDPEPWPGIV CLVEHPITNV 
      2560       2570       2580       2590       2600
QRNDDVNYPV IVSVRLGPDC QLMQPYNDLN LSGGTDPDPD PEPDPDPEPG 
      2610       2620       2630       2640       2650
PDPEPGVDEL DLSKYIPNQL IDLLICNSYV PNNVSVDFLS TYPNLNFSIH 
      2660       2670       2680       2690       2700
NITDVVVSSK PYTLALFETE SQINSASVWR GDLTQLSVFI QYKFYTRVEA 
      2710       2720       2730       2740       2750
YNKVTTVHTD KWTPNFDGTV YKPVDVKIEH AYGTYELTTM WLTSYGLVME 
      2760       2770       2780       2790       2800
WSLDESRVFY GTYKTDSNGR RWLIDGNTPI ARSDHCFIVS SPDLLSDDKA 
      2810       2820       2830       2840       2850
YYNNPIGAKQ GGKLVDGAQI YRIFKTESGG YRSDPFVPET YWPSETPYNA 
      2860       2870       2880       2890       2900
DWSGVKMPYQ IRKVIQTGNN LAGKHLDGDL KMCAMIRQGS SSTQSTDNYF 
      2910       2920       2930       2940       2950
YPIYVHNFSA LLKQMNLILK ERKTKYIKFD LQVGGKPFAQ MGFGDGAFIG 
      2960       2970       2980       2990       3000
RTTMFRQIRA AITNVILLKN IVGVDDLSGL QALPTSGFAD WVVKAQSTNS 
      3010       3020       3030       3040       3050
KFLNDFYNDK ISIERQASLG IAAAIGAGQG LFGGLSAQWQ WQQQADWSRQ 
      3060       3070       3080       3090       3100
MQRERLDMME KLANINNQAR LNQLTQSGAQ QRITQQAAYQ QQMNALGAGS 
      3110       3120       3130       3140       3150
VSAQNGMYTP SNYTPLPSYK SNTTNYYNNS VYHTDNNITN NPSNTSLTNN 
      3160       3170       3180       3190       3200
INNFNPELFQ QQRERMPTPS EAYDNSKGFV PQPGTSKSIA TENINPNYKD 
      3210       3220       3230       3240       3250
EEHIYEPIEQ QNHEYADIDY NAMNISRENK NSSNFGNVGI LDHQYADIDY 
      3260       3270       3280       3290       3300
DAMKIARDQQ NSSKFGNVGV LNHQYAELDF SKNNTRKNSQ ILDNSLYSKT 
      3310       3320       3330       3340       3350
QPSSKMIDNS LYGINPNKMV ENQNYEPASM ERKNSIYSSN LNSSNNLKFN 
      3360       3370       3380       3390
NIPNFKGPTN LNISGAKPAG FGSGIIQPAI NKYTDFSKPN
Note: Produced by -1 ribosomal frameshifting.1 Publication
Length:3,390
Mass (Da):390,107
Last modified:November 22, 2017 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i03A54D0B18E90BF6
GO
Isoform Polyprotein (identifier: C1JCT1-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry C1JCT1.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by conventional translation.1 Publication
Length:2,580
Mass (Da):299,117
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
FJ528584 Genomic RNA Translation: ACO37272.1

NCBI Reference Sequences

More...RefSeqi		YP_002790880.2, NC_012531.1 [C1JCT2-1]

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		7751222

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		vg:7751222

Keywords - Coding sequence diversityi

Ribosomal frameshifting

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ528584 Genomic RNA Translation: ACO37272.1
RefSeqiYP_002790880.2, NC_012531.1 [C1JCT2-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

PTM databases

iPTMnetiC1JCT2

Genome annotation databases

GeneIDi7751222
KEGGivg:7751222

Phylogenomic databases

OrthoDBi2102at10239

Family and domain databases

Gene3Di2.60.120.20, 1 hit
InterProiView protein in InterPro
IPR000605 Helicase_SF3_ssDNA/RNA_vir
IPR014759 Helicase_SF3_ssRNA_vir
IPR027417 P-loop_NTPase
IPR009003 Peptidase_S1_PA
IPR001205 RNA-dir_pol_C
IPR007094 RNA-dir_pol_PSvirus
IPR029053 Viral_coat
PfamiView protein in Pfam
PF00680 RdRP_1, 1 hit
PF00910 RNA_helicase, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51874 PCV_3C_PRO, 1 hit
PS50507 RDRP_SSRNA_POS, 1 hit
PS51218 SF3_HELICASE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPOLFS_SINV3
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C1JCT2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2017
Last sequence update: November 22, 2017
Last modified: September 18, 2019
This is version 28 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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