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Entry version 91 (12 Aug 2020)
Sequence version 1 (26 May 2009)
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Protein
Submitted name:

Cytochrome P450 2D6

Gene

CYP2D6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

hemeARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotationARBA annotation, Iron, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Cytochrome P450 2D6Imported
Submitted name:
Cytochrome P450, family 2, subfamily D, polypeptide 6, isoform CRA_aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CYP2D6Imported
ORF Names:hCG_41551Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000100197.20

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei6 – 23HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000100197, Expressed in right lobe of liver and 111 other tissues

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotationARBA annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K17712

Identification of Orthologs from Complete Genome Data

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OMAi
GGIWPVD

Database of Orthologous Groups

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OrthoDBi
702827at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.630.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001128, Cyt_P450
IPR017972, Cyt_P450_CS
IPR002401, Cyt_P450_E_grp-I
IPR008069, Cyt_P450_E_grp-I_CYP2D-like
IPR036396, Cyt_P450_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00067, p450, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00463, EP450I
PR01686, EP450ICYP2D
PR00385, P450

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48264, SSF48264, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00086, CYTOCHROME_P450, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C1ID52-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLEALVPLA VIVAIFLLLV DLMHRRQRWA ARYPPGPLPL PGLGNLLHVD
60 70 80 90 100
FQNTPYCFDQ LRRRFGDVFS LQLAWTPVVV LNGLAAVREA LVTHGEDTAD
110 120 130 140 150
RPPVPITQIL GFGPRSQGVF LARYGPAWRE QRRFSVSTLR NLGLGKKSLE
160 170 180 190 200
QWVTEEAACL CAAFANHSGR PFRPNGLLDK AVSNVIASLT CGRRFEYDDP
210 220 230 240 250
RFLRLLDLAQ EGLKEESGFL REVLNAVPVL LHIPALAGKV LRFQKAFLTQ
260 270 280 290 300
LDELLTEHRM TWDPAQPPRD LTEAFLAEME KAKGNPESSF NDENLRIVVA
310 320 330 340 350
DLFSAGMVTT STTLAWGLLL MILHPDVQRR VQQEIDDVIG QVRRPEMGDQ
360 370 380 390 400
AHMPYTTAVI HEVQRFGDIV PLGVTHMTSR DIEVQGFRIP KGTTLITNLS
410 420 430 440 450
SVLKDEAVWE KPFRFHPEHF LDAQGHFVKP EAFLPFSAGR RACLGEPLAR
460 470 480 490
MELFLFFTSL LQHFSFSVPT GQPRPSHHGV FAFLVSPSPY ELCAVPR
Length:497
Mass (Da):55,769
Last modified:May 26, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i542B1D505DF3CDAC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EU530602 Genomic DNA Translation: ACB41742.1
EU530603 Genomic DNA Translation: ACB41743.1
GU586977 Genomic DNA Translation: ADF36208.1
GU586978 Genomic DNA Translation: ADF36209.1
GU586980 Genomic DNA Translation: ADF36211.1
GU586987 Genomic DNA Translation: ADF36218.1
GU586989 Genomic DNA Translation: ADF36220.1
GU586990 Genomic DNA Translation: ADF36221.1
GU586992 Genomic DNA Translation: ADF36223.1
GU586999 Genomic DNA Translation: ADF36230.1
GU587002 Genomic DNA Translation: ADF36233.1
GU587007 Genomic DNA Translation: ADF36238.1
GU587015 Genomic DNA Translation: ADF36246.1
GU587016 Genomic DNA Translation: ADF36247.1
GU587023 Genomic DNA Translation: ADF36254.1
GU587025 Genomic DNA Translation: ADF36256.1
GU587026 Genomic DNA Translation: ADF36257.1
GU587035 Genomic DNA Translation: ADF36266.1
GU587039 Genomic DNA Translation: ADF36270.1
GU587040 Genomic DNA Translation: ADF36271.1
GU587042 Genomic DNA Translation: ADF36273.1
GU587045 Genomic DNA Translation: ADF36276.1
GU587047 Genomic DNA Translation: ADF36278.1
GU587051 Genomic DNA Translation: ADF36282.1
GU587054 Genomic DNA Translation: ADF36285.1
GU587056 Genomic DNA Translation: ADF36287.1
GU587058 Genomic DNA Translation: ADF36289.1
GU587061 Genomic DNA Translation: ADF36292.1
GU587068 Genomic DNA Translation: ADF36298.1
GU587076 Genomic DNA Translation: ADF36305.1
GU587078 Genomic DNA Translation: ADF36307.1
GU587080 Genomic DNA Translation: ADF36309.1
GU587085 Genomic DNA Translation: ADF36314.1
GU587087 Genomic DNA Translation: ADF36316.1
GU587088 Genomic DNA Translation: ADF36317.1
GU587089 Genomic DNA Translation: ADF36318.1
GU587090 Genomic DNA Translation: ADF36319.1
GU587091 Genomic DNA Translation: ADF36320.1
GU587092 Genomic DNA Translation: ADF36321.1
GU587095 Genomic DNA Translation: ADF36324.1
GU587096 Genomic DNA Translation: ADF36325.1
GU587097 Genomic DNA Translation: ADF36326.1
GU587098 Genomic DNA Translation: ADF36327.1
GU587099 Genomic DNA Translation: ADF36328.1
GU587101 Genomic DNA Translation: ADF36330.1
GU587102 Genomic DNA Translation: ADF36331.1
GU587105 Genomic DNA Translation: ADF36333.1
GU587106 Genomic DNA Translation: ADF36334.1
GU587107 Genomic DNA Translation: ADF36335.1
GU587108 Genomic DNA Translation: ADF36336.1
GU587109 Genomic DNA Translation: ADF36337.1
GU587110 Genomic DNA Translation: ADF36338.1
GU587111 Genomic DNA Translation: ADF36339.1
GU587112 Genomic DNA Translation: ADF36340.1
GU587113 Genomic DNA Translation: ADF36341.1
GU587117 Genomic DNA Translation: ADF36345.1
GU587119 Genomic DNA Translation: ADF36347.1
GU587120 Genomic DNA Translation: ADF36348.1
GU587121 Genomic DNA Translation: ADF36349.1
GU587122 Genomic DNA Translation: ADF36350.1
GU587125 Genomic DNA Translation: ADF36353.1
GU587126 Genomic DNA Translation: ADF36354.1
GU587131 Genomic DNA Translation: ADF36358.1
GU587145 Genomic DNA Translation: ADF36371.1
GU587147 Genomic DNA Translation: ADF36373.1
GU587149 Genomic DNA Translation: ADF36375.1
GU587150 Genomic DNA Translation: ADF36376.1
GU587151 Genomic DNA Translation: ADF36377.1
GU587153 Genomic DNA Translation: ADF36379.1
GU587155 Genomic DNA Translation: ADF36381.1
GU587156 Genomic DNA Translation: ADF36382.1
GU587157 Genomic DNA Translation: ADF36383.1
GU587158 Genomic DNA Translation: ADF36384.1
GU587159 Genomic DNA Translation: ADF36385.1
GU587161 Genomic DNA Translation: ADF36387.1
GU587162 Genomic DNA Translation: ADF36388.1
GU587163 Genomic DNA Translation: ADF36389.1
GU587164 Genomic DNA Translation: ADF36390.1
GU587165 Genomic DNA Translation: ADF36391.1
GU587167 Genomic DNA Translation: ADF36393.1
GU587168 Genomic DNA Translation: ADF36394.1
GU587170 Genomic DNA Translation: ADF36396.1
GU587171 Genomic DNA Translation: ADF36397.1
GU587172 Genomic DNA Translation: ADF36398.1
GU587175 Genomic DNA Translation: ADF36401.1
GU587176 Genomic DNA Translation: ADF36402.1
GU587177 Genomic DNA Translation: ADF36403.1
GU587179 Genomic DNA Translation: ADF36405.1
GU587181 Genomic DNA Translation: ADF36407.1
GU587182 Genomic DNA Translation: ADF36408.1
GU587185 Genomic DNA Translation: ADF36411.1
GU587186 Genomic DNA Translation: ADF36412.1
GU587187 Genomic DNA Translation: ADF36413.1
GU587188 Genomic DNA Translation: ADF36414.1
GU587190 Genomic DNA Translation: ADF36416.1
GU587191 Genomic DNA Translation: ADF36417.1
GU587193 Genomic DNA Translation: ADF36419.1
GU587197 Genomic DNA Translation: ADF36423.1
GU587203 Genomic DNA Translation: ADF36429.1
GU587204 Genomic DNA Translation: ADF36430.1
GU587205 Genomic DNA Translation: ADF36431.1
GU587209 Genomic DNA Translation: ADF36435.1
GU587215 Genomic DNA Translation: ADF36441.1
GU587217 Genomic DNA Translation: ADF36443.1
GU587223 Genomic DNA Translation: ADF36449.1
GU587227 Genomic DNA Translation: ADF36453.1
GU587229 Genomic DNA Translation: ADF36455.1
GU587232 Genomic DNA Translation: ADF36458.1
GU587233 Genomic DNA Translation: ADF36459.1
GU587234 Genomic DNA Translation: ADF36460.1
GU587236 Genomic DNA Translation: ADF36462.1
GU587237 Genomic DNA Translation: ADF36463.1
GU587238 Genomic DNA Translation: ADF36464.1
GU587239 Genomic DNA Translation: ADF36465.1
GU587242 Genomic DNA Translation: ADF36468.1
GU587246 Genomic DNA Translation: ADF36472.1
GU587248 Genomic DNA Translation: ADF36474.1
GU587250 Genomic DNA Translation: ADF36476.1
GU587252 Genomic DNA Translation: ADF36478.1
CH471095 Genomic DNA Translation: EAW60492.1

NCBI Reference Sequences

More...
RefSeqi
NP_000097.3, NM_000106.5

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
1565

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:1565

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU530602 Genomic DNA Translation: ACB41742.1
EU530603 Genomic DNA Translation: ACB41743.1
GU586977 Genomic DNA Translation: ADF36208.1
GU586978 Genomic DNA Translation: ADF36209.1
GU586980 Genomic DNA Translation: ADF36211.1
GU586987 Genomic DNA Translation: ADF36218.1
GU586989 Genomic DNA Translation: ADF36220.1
GU586990 Genomic DNA Translation: ADF36221.1
GU586992 Genomic DNA Translation: ADF36223.1
GU586999 Genomic DNA Translation: ADF36230.1
GU587002 Genomic DNA Translation: ADF36233.1
GU587007 Genomic DNA Translation: ADF36238.1
GU587015 Genomic DNA Translation: ADF36246.1
GU587016 Genomic DNA Translation: ADF36247.1
GU587023 Genomic DNA Translation: ADF36254.1
GU587025 Genomic DNA Translation: ADF36256.1
GU587026 Genomic DNA Translation: ADF36257.1
GU587035 Genomic DNA Translation: ADF36266.1
GU587039 Genomic DNA Translation: ADF36270.1
GU587040 Genomic DNA Translation: ADF36271.1
GU587042 Genomic DNA Translation: ADF36273.1
GU587045 Genomic DNA Translation: ADF36276.1
GU587047 Genomic DNA Translation: ADF36278.1
GU587051 Genomic DNA Translation: ADF36282.1
GU587054 Genomic DNA Translation: ADF36285.1
GU587056 Genomic DNA Translation: ADF36287.1
GU587058 Genomic DNA Translation: ADF36289.1
GU587061 Genomic DNA Translation: ADF36292.1
GU587068 Genomic DNA Translation: ADF36298.1
GU587076 Genomic DNA Translation: ADF36305.1
GU587078 Genomic DNA Translation: ADF36307.1
GU587080 Genomic DNA Translation: ADF36309.1
GU587085 Genomic DNA Translation: ADF36314.1
GU587087 Genomic DNA Translation: ADF36316.1
GU587088 Genomic DNA Translation: ADF36317.1
GU587089 Genomic DNA Translation: ADF36318.1
GU587090 Genomic DNA Translation: ADF36319.1
GU587091 Genomic DNA Translation: ADF36320.1
GU587092 Genomic DNA Translation: ADF36321.1
GU587095 Genomic DNA Translation: ADF36324.1
GU587096 Genomic DNA Translation: ADF36325.1
GU587097 Genomic DNA Translation: ADF36326.1
GU587098 Genomic DNA Translation: ADF36327.1
GU587099 Genomic DNA Translation: ADF36328.1
GU587101 Genomic DNA Translation: ADF36330.1
GU587102 Genomic DNA Translation: ADF36331.1
GU587105 Genomic DNA Translation: ADF36333.1
GU587106 Genomic DNA Translation: ADF36334.1
GU587107 Genomic DNA Translation: ADF36335.1
GU587108 Genomic DNA Translation: ADF36336.1
GU587109 Genomic DNA Translation: ADF36337.1
GU587110 Genomic DNA Translation: ADF36338.1
GU587111 Genomic DNA Translation: ADF36339.1
GU587112 Genomic DNA Translation: ADF36340.1
GU587113 Genomic DNA Translation: ADF36341.1
GU587117 Genomic DNA Translation: ADF36345.1
GU587119 Genomic DNA Translation: ADF36347.1
GU587120 Genomic DNA Translation: ADF36348.1
GU587121 Genomic DNA Translation: ADF36349.1
GU587122 Genomic DNA Translation: ADF36350.1
GU587125 Genomic DNA Translation: ADF36353.1
GU587126 Genomic DNA Translation: ADF36354.1
GU587131 Genomic DNA Translation: ADF36358.1
GU587145 Genomic DNA Translation: ADF36371.1
GU587147 Genomic DNA Translation: ADF36373.1
GU587149 Genomic DNA Translation: ADF36375.1
GU587150 Genomic DNA Translation: ADF36376.1
GU587151 Genomic DNA Translation: ADF36377.1
GU587153 Genomic DNA Translation: ADF36379.1
GU587155 Genomic DNA Translation: ADF36381.1
GU587156 Genomic DNA Translation: ADF36382.1
GU587157 Genomic DNA Translation: ADF36383.1
GU587158 Genomic DNA Translation: ADF36384.1
GU587159 Genomic DNA Translation: ADF36385.1
GU587161 Genomic DNA Translation: ADF36387.1
GU587162 Genomic DNA Translation: ADF36388.1
GU587163 Genomic DNA Translation: ADF36389.1
GU587164 Genomic DNA Translation: ADF36390.1
GU587165 Genomic DNA Translation: ADF36391.1
GU587167 Genomic DNA Translation: ADF36393.1
GU587168 Genomic DNA Translation: ADF36394.1
GU587170 Genomic DNA Translation: ADF36396.1
GU587171 Genomic DNA Translation: ADF36397.1
GU587172 Genomic DNA Translation: ADF36398.1
GU587175 Genomic DNA Translation: ADF36401.1
GU587176 Genomic DNA Translation: ADF36402.1
GU587177 Genomic DNA Translation: ADF36403.1
GU587179 Genomic DNA Translation: ADF36405.1
GU587181 Genomic DNA Translation: ADF36407.1
GU587182 Genomic DNA Translation: ADF36408.1
GU587185 Genomic DNA Translation: ADF36411.1
GU587186 Genomic DNA Translation: ADF36412.1
GU587187 Genomic DNA Translation: ADF36413.1
GU587188 Genomic DNA Translation: ADF36414.1
GU587190 Genomic DNA Translation: ADF36416.1
GU587191 Genomic DNA Translation: ADF36417.1
GU587193 Genomic DNA Translation: ADF36419.1
GU587197 Genomic DNA Translation: ADF36423.1
GU587203 Genomic DNA Translation: ADF36429.1
GU587204 Genomic DNA Translation: ADF36430.1
GU587205 Genomic DNA Translation: ADF36431.1
GU587209 Genomic DNA Translation: ADF36435.1
GU587215 Genomic DNA Translation: ADF36441.1
GU587217 Genomic DNA Translation: ADF36443.1
GU587223 Genomic DNA Translation: ADF36449.1
GU587227 Genomic DNA Translation: ADF36453.1
GU587229 Genomic DNA Translation: ADF36455.1
GU587232 Genomic DNA Translation: ADF36458.1
GU587233 Genomic DNA Translation: ADF36459.1
GU587234 Genomic DNA Translation: ADF36460.1
GU587236 Genomic DNA Translation: ADF36462.1
GU587237 Genomic DNA Translation: ADF36463.1
GU587238 Genomic DNA Translation: ADF36464.1
GU587239 Genomic DNA Translation: ADF36465.1
GU587242 Genomic DNA Translation: ADF36468.1
GU587246 Genomic DNA Translation: ADF36472.1
GU587248 Genomic DNA Translation: ADF36474.1
GU587250 Genomic DNA Translation: ADF36476.1
GU587252 Genomic DNA Translation: ADF36478.1
CH471095 Genomic DNA Translation: EAW60492.1
RefSeqiNP_000097.3, NM_000106.5

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
13178, 597 antibodies

Genome annotation databases

GeneIDi1565
KEGGihsa:1565

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1565
EuPathDBiHostDB:ENSG00000100197.20

Phylogenomic databases

KOiK17712
OMAiGGIWPVD
OrthoDBi702827at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
1565, 5 hits in 868 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
1565

Gene expression databases

BgeeiENSG00000100197, Expressed in right lobe of liver and 111 other tissues

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128, Cyt_P450
IPR017972, Cyt_P450_CS
IPR002401, Cyt_P450_E_grp-I
IPR008069, Cyt_P450_E_grp-I_CYP2D-like
IPR036396, Cyt_P450_sf
PfamiView protein in Pfam
PF00067, p450, 1 hit
PRINTSiPR00463, EP450I
PR01686, EP450ICYP2D
PR00385, P450
SUPFAMiSSF48264, SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086, CYTOCHROME_P450, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC1ID52_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C1ID52
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: August 12, 2020
This is version 91 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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