Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

ATP-dependent Clp protease ATP-binding subunit ClpX

Gene

clpX

Organism
Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.UniRule annotationSAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi123 – 130ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation, Hydrolase, ProteaseImported
LigandATP-bindingUniRule annotationSAAS annotationImported, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyciACAP240015:G1GV4-3293-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent Clp protease ATP-binding subunit ClpXUniRule annotationSAAS annotation
Gene namesi
Name:clpXUniRule annotationImported
Ordered Locus Names:ACP_3432Imported
OrganismiAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)Imported
Taxonomic identifieri240015 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium
Proteomesi
  • UP000002207 Componenti: Chromosome

Interactioni

Subunit structurei

Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.UniRule annotationSAAS annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi240015.ACP_3432

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 53zf-C4_ClpXInterPro annotationAdd BLAST44
Domaini114 – 267AAAInterPro annotationAdd BLAST154
Domaini326 – 419ClpB_D2-smallInterPro annotationAdd BLAST94

Sequence similaritiesi

Belongs to the ClpX chaperone family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CHN Bacteria
COG1219 LUCA
HOGENOMiHOG000010093
KOiK03544
OMAiDIMYDLP
OrthoDBiPOG091H01U4

Family and domain databases

Gene3Di3.30.50.30, 1 hit
HAMAPiMF_00175 ClpX, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR019489 Clp_ATPase_C
IPR004487 Clp_protease_ATP-bd_su_ClpX
IPR027417 P-loop_NTPase
IPR010603 Znf_CppX_C4
IPR038366 Znf_CppX_C4_sf
PANTHERiPTHR11262 PTHR11262, 2 hits
PfamiView protein in Pfam
PF07724 AAA_2, 1 hit
PF10431 ClpB_D2-small, 1 hit
PF06689 zf-C4_ClpX, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM01086 ClpB_D2-small, 1 hit
SM00994 zf-C4_ClpX, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00382 clpX, 1 hit

Sequencei

Sequence statusi: Complete.

C1F6W3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTRTGSDDS LRCSFCHKSQ DAVAKLISSP SDYPRAYICD ECVAVCNSIL
60 70 80 90 100
EDDRAEAPAG AAPTQLPKPL EVKAFLDEYV IGQEQTKKKL AVAVYNHYKR
110 120 130 140 150
IQMNRTRGND VELAKSNILL VGPTGSGKTL LAHTLAKMLD VPFAIVDATT
160 170 180 190 200
LTEAGYVGED VENIILKLLQ AADGDVARAQ TGIIYIDEID KIGRKDENPS
210 220 230 240 250
ITRDVSGEGV QQALLKILEG TVANVPPQGG RKHPHQEFTP VDTTNILFIC
260 270 280 290 300
GGAFVGLERV VGRRVGKKAL GFKAIAEKDQ QENGQTTRTQ RDTELLRMAE
310 320 330 340 350
PQDLIRYGLI PEFVGRLPVI GILDELDEAA LVEILTKPRN AILKQYQKLF
360 370 380 390 400
EFEGVNLVFS EEAAHAIALE ALDRKVGARG LRMILEELML DLMYHLPSNK
410 420
RVSDLVIDAE MVKKRDLSLS LLDKAG
Length:426
Mass (Da):46,843
Last modified:May 26, 2009 - v1
Checksum:i7673666AE03C4B9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001472 Genomic DNA Translation: ACO31650.1
RefSeqiWP_015898461.1, NC_012483.1

Genome annotation databases

EnsemblBacteriaiACO31650; ACO31650; ACP_3432
KEGGiaca:ACP_3432

Similar proteinsi

Entry informationi

Entry nameiC1F6W3_ACIC5
AccessioniPrimary (citable) accession number: C1F6W3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: March 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health