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Protein

Transaldolase

Gene

tal

Organism
Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (ACP_0832), Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei136Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

BioCyciACAP240015:G1GV4-2510-MONOMER
UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:ACP_2636
OrganismiAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)
Taxonomic identifieri240015 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium
Proteomesi
  • UP000002207 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001984481 – 333TransaldolaseAdd BLAST333

Proteomic databases

PRIDEiC1F2H6

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi240015.ACP_2636

Structurei

3D structure databases

SMRiC1F2H6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CW3 Bacteria
COG0176 LUCA
HOGENOMiHOG000281234
KOiK00616
OMAiMAFDKLH
OrthoDBiPOG091H05RO

Family and domain databases

CDDicd00957 Transaldolase_TalAB, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00492 Transaldolase_1, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001585 TAL/FSA
IPR004730 Transaldolase_1
IPR018225 Transaldolase_AS
PANTHERiPTHR10683 PTHR10683, 1 hit
PTHR10683:SF20 PTHR10683:SF20, 1 hit
PfamiView protein in Pfam
PF00923 TAL_FSA, 1 hit
TIGRFAMsiTIGR00874 talAB, 1 hit
PROSITEiView protein in PROSITE
PS01054 TRANSALDOLASE_1, 1 hit
PS00958 TRANSALDOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

C1F2H6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQSLLAQLR KMTTVVADTG DIQAIEKVRP QDATTNPSLI TAAAGMPAYQ
60 70 80 90 100
KIVDDTLLDA KKQLGDSAPS DKVAKLAFEN LAVAFGKQIL AIIPGRVSTE
110 120 130 140 150
VDARLSYDTE ATIKQAHAII EKYQKQGIGR ERVLIKIAST WEGIRAAEQL
160 170 180 190 200
EKEGIHCNLT LLFGMHQAVA CAEAGVTLIS PFVGRILDWY KKDTGKDYVG
210 220 230 240 250
ADDPGVQSVT RIYNYFKKFG YKTVVMGASF RNTGEIIELA GCDLLTISPK
260 270 280 290 300
LLEELDAKEA ELPRKLDAEK AKGMEIERIT VDKATFDKMH AEDRMAHDKL
310 320 330
KEGIEGFSEA LENLEKLLAK RLEELSAEPV GAK
Length:333
Mass (Da):36,553
Last modified:May 26, 2009 - v1
Checksum:i970E73E7F2BE8BAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001472 Genomic DNA Translation: ACO31507.1
RefSeqiWP_015897701.1, NC_012483.1

Genome annotation databases

EnsemblBacteriaiACO31507; ACO31507; ACP_2636
KEGGiaca:ACP_2636

Similar proteinsi

Entry informationi

Entry nameiTAL_ACIC5
AccessioniPrimary (citable) accession number: C1F2H6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: February 28, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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