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Protein
Submitted name:

Probable N-acetylglucosamine-6-phosphate deacetylase

Gene

nagA

Organism
Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi133Divalent metal cationUniRule annotation1
Binding sitei144Substrate; via amide nitrogenUniRule annotation1
Metal bindingi199Divalent metal cation; via tele nitrogenUniRule annotation1
Metal bindingi220Divalent metal cation; via tele nitrogenUniRule annotation1
Binding sitei231SubstrateUniRule annotation1
Binding sitei255Substrate; via tele nitrogenUniRule annotation1
Active sitei278Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationImported
Biological processCarbohydrate metabolismUniRule annotation
LigandMetal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciBBRE358681:G1G2J-4584-MONOMER

Protein family/group databases

MEROPSiM38.983

Names & Taxonomyi

Protein namesi
Submitted name:
Probable N-acetylglucosamine-6-phosphate deacetylaseImported (EC:3.5.1.25Imported)
Gene namesi
Name:nagAImported
Ordered Locus Names:BBR47_44880Imported
OrganismiBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)Imported
Taxonomic identifieri358681 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaeBrevibacillus
Proteomesi
  • UP000001877 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi358681.BBR47_44880

Structurei

3D structure databases

ProteinModelPortaliC0ZJ90
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 384Amidohydro-relInterPro annotationAdd BLAST330

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni223 – 224Substrate bindingUniRule annotation2
Regioni311 – 313Substrate bindingUniRule annotation3

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. NagA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CE4 Bacteria
COG1820 LUCA
HOGENOMiHOG000275009
KOiK01443
OMAiHAFNAMP
OrthoDBiPOG091H03KA

Family and domain databases

CDDicd00854 NagA, 1 hit
Gene3Di2.30.40.10, 2 hits
InterProiView protein in InterPro
IPR006680 Amidohydro-rel
IPR003764 GlcNAc_6-P_deAcase
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PANTHERiPTHR11113:SF1 PTHR11113:SF1, 1 hit
PfamiView protein in Pfam
PF01979 Amidohydro_1, 1 hit
PIRSFiPIRSF038994 NagA, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR00221 nagA, 1 hit

Sequencei

Sequence statusi: Complete.

C0ZJ90-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNQEYALKGK LVADGQELHN GLVVVGNGTI TYAGKAEEYG KALPDHVVTV
60 70 80 90 100
EDSWICPGFV DMHMHGIDGY DTMDGTPESL QAISTALARH GVTSFLATTM
110 120 130 140 150
TAPYAQLEQV LVNIAQNSKE GLLGAQAIGI HLEGPWINPR YKGAQKEENI
160 170 180 190 200
AIPKLDAVQK LYGLSEGLIK VVTIAPEQPE ALEAIAWLKE RDVIVSAGHT
210 220 230 240 250
GATFAQATEA VDAGVRHFTH CFNAMTGLHH REPGVVGAAM YHEQLSTELI
260 270 280 290 300
ADGIHVHPAV MKILYRVKTA ERLALVSDSM RAAAMGEGTY DLGGQEVHVH
310 320 330 340 350
DNQAKLADGT LAGSILTLNR AVGNMVTLSG VSLPDAVEMA SLTPASILGF
360 370 380
GERKGRLAAG YDADITVLNT QFDVTMTFVA GKEVYHQSK
Length:389
Mass (Da):41,545
Last modified:May 26, 2009 - v1
Checksum:i1832EFC10779B8F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008955 Genomic DNA Translation: BAH45465.1
RefSeqiWP_015892727.1, NC_012491.1

Genome annotation databases

EnsemblBacteriaiBAH45465; BAH45465; BBR47_44880
GeneIDi29261729
KEGGibbe:BBR47_44880

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008955 Genomic DNA Translation: BAH45465.1
RefSeqiWP_015892727.1, NC_012491.1

3D structure databases

ProteinModelPortaliC0ZJ90
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi358681.BBR47_44880

Protein family/group databases

MEROPSiM38.983

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAH45465; BAH45465; BBR47_44880
GeneIDi29261729
KEGGibbe:BBR47_44880

Phylogenomic databases

eggNOGiENOG4105CE4 Bacteria
COG1820 LUCA
HOGENOMiHOG000275009
KOiK01443
OMAiHAFNAMP
OrthoDBiPOG091H03KA

Enzyme and pathway databases

BioCyciBBRE358681:G1G2J-4584-MONOMER

Family and domain databases

CDDicd00854 NagA, 1 hit
Gene3Di2.30.40.10, 2 hits
InterProiView protein in InterPro
IPR006680 Amidohydro-rel
IPR003764 GlcNAc_6-P_deAcase
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PANTHERiPTHR11113:SF1 PTHR11113:SF1, 1 hit
PfamiView protein in Pfam
PF01979 Amidohydro_1, 1 hit
PIRSFiPIRSF038994 NagA, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR00221 nagA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC0ZJ90_BREBN
AccessioniPrimary (citable) accession number: C0ZJ90
Entry historyiIntegrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: October 10, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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