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Protein

Ribose 1,5-bisphosphate phosphokinase PhnN

Gene

phnN

Organism
Brucella melitensis biotype 2 (strain ATCC 23457)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).UniRule annotation

Catalytic activityi

ATP + alpha-D-ribose 1,5-bisphosphate = ADP + 5-phospho-alpha-D-ribose 1-diphosphate.UniRule annotation

Pathwayi: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. Ribose 1,5-bisphosphate phosphokinase PhnN (phnN)
This subpathway is part of the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II), the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis and in Metabolic intermediate biosynthesis.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi15 – 22ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00087; UER00175

Names & Taxonomyi

Protein namesi
Recommended name:
Ribose 1,5-bisphosphate phosphokinase PhnNUniRule annotation (EC:2.7.4.23UniRule annotation)
Alternative name(s):
Ribose 1,5-bisphosphokinaseUniRule annotation
Gene namesi
Name:phnNUniRule annotation
Ordered Locus Names:BMEA_A1146
OrganismiBrucella melitensis biotype 2 (strain ATCC 23457)
Taxonomic identifieri546272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000001748 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004127751 – 192Ribose 1,5-bisphosphate phosphokinase PhnNAdd BLAST192

Structurei

3D structure databases

ProteinModelPortaliC0RJ73
SMRiC0RJ73
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribose 1,5-bisphosphokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037637
KOiK05774
OMAiMARLIWL

Family and domain databases

HAMAPiMF_00836 PhnN, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR027417 P-loop_NTPase
IPR012699 PhnN
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR02322 phosphon_PhnN, 1 hit

Sequencei

Sequence statusi: Complete.

C0RJ73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQADTPKGCF VAVVGPSGAG KDTIMDAARV ALSGDMRFHF VRRIITRTQM
60 70 80 90 100
PGTEDHDSLD EADFARAAGE GRFALHWQAH GLRYGLPKTL DDEIAGGAVV
110 120 130 140 150
IANVSRRVLS DIRRLYTSRS VVVISARTEV LAQRLASRGR ESREEIAARL
160 170 180 190
AREVGFDDGS GDVVTIDNSG EVGASTKAFL HHLHEIAVKT IA
Length:192
Mass (Da):20,737
Last modified:May 5, 2009 - v1
Checksum:iE5715D45AEDB88DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001488 Genomic DNA Translation: ACO00881.1
RefSeqiWP_004685664.1, NC_012441.1

Genome annotation databases

EnsemblBacteriaiACO00881; ACO00881; BMEA_A1146
GeneIDi29593698
KEGGibmi:BMEA_A1146

Entry informationi

Entry nameiPHNN_BRUMB
AccessioniPrimary (citable) accession number: C0RJ73
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: May 5, 2009
Last modified: June 7, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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