Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Pol protein

Gene

pol

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl proteaseUniRule annotation, Hydrolase, Multifunctional enzymeSAAS annotation, Nucleotidyltransferase, Protease, RNA-directed DNA polymeraseSAAS annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Pol proteinImported
Gene namesi
Name:polImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesOrterviralesRetroviridaeOrthoretrovirinaeLentivirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 117Peptidase A2InterPro annotationAdd BLAST70
Domaini171 – 361Reverse transcriptaseInterPro annotationAdd BLAST191

Sequence similaritiesi

Belongs to the retroviral Pol polyprotein family.UniRule annotation

Family and domain databases

CDDicd05482 HIV_retropepsin_like, 1 hit
Gene3Di2.40.70.10, 1 hit
InterProiView protein in InterPro
IPR001969 Aspartic_peptidase_AS
IPR001995 Peptidase_A2_cat
IPR021109 Peptidase_aspartic_dom_sf
IPR034170 Retropepsin-like_cat_dom
IPR018061 Retropepsins
IPR000477 RT_dom
IPR010659 RVT_connect
IPR010661 RVT_thumb
PfamiView protein in Pfam
PF00077 RVP, 1 hit
PF00078 RVT_1, 1 hit
PF06815 RVT_connect, 1 hit
PF06817 RVT_thumb, 1 hit
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS50175 ASP_PROT_RETROV, 1 hit
PS00141 ASP_PROTEASE, 1 hit
PS50878 RT_POL, 1 hit

Sequencei

Sequence statusi: Fragment.

C0LQD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RRLGDGGGES LCTEAGAERQ GTSSSLNFPQ ITLWQRPLVT VKIGGQLKEA
60 70 80 90 100
LLDTGADDTV LEDINLPGKW KPKMIGGIGG FIKVRQYDQI QIEICGKKAI
110 120 130 140 150
GTVLVGPTPV NIIGRNMLTQ IGCTLNFPIS PIDTVPVTLK PGMDGPKVKQ
160 170 180 190 200
WPLTEEKIKA LTEICKEMEE EGKISKIGPE NPYNTPVFAI KKKDSTKWRK
210 220 230 240 250
LVDFRELNKR TQDFWEVQLG IPHPAGLKKK KSVTVLDVGD AYFSVPLDES
260 270 280 290 300
FRKYTAFTIP SINNETPGIR YQYNVLPQGW KGSPAIFQSS MTKILEPYKI
310 320 330 340 350
KNPEMVIYQY MDDLYVGSDL EIGQHRIKIE ELRAHLLSWG FTTPDKKHQK
360 370 380 390 400
EPPFLWMGYE LHPDKWTVQP IELPEKDHWT VNDIQKLVGK LNWASQIYPG
410 420 430 440 450
IKIKQLCKLL RGAKALTDII PLTEEAELEL AENREILKTP VHGVYYDPSK
460 470 480 490 500
DLVAEVQKQG QDQWTYQIYQ EPYKNLKTGK YARKRSAHTN DVRQLAEVVQ
510 520 530 540 550
KIATESIVIW GKTPKFKLPI QRETWETWWT EYWQATWIPE WEFVNTPPLV
560
KLWYQLEKDP IMGAE
Length:565
Mass (Da):64,681
Last modified:May 5, 2009 - v1
Checksum:iE31B0A5FA6C3A5D0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei565Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ752417 Genomic RNA Translation: ACN66488.1

Similar proteinsi

Entry informationi

Entry nameiC0LQD3_9HIV1
AccessioniPrimary (citable) accession number: C0LQD3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 5, 2009
Last modified: July 18, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health