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Entry version 89 (29 Sep 2021)
Sequence version 1 (05 May 2009)
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Protein

LRR receptor-like serine/threonine-protein kinase RGI2

Gene

RGI2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Together with RGI1, RGI3, RGI4 and RGI5, acts as receptor of RGF peptides (e.g. RGF1, GLV5/CLEL1/RGF2, GLV7/CLEL3/RGF3, GLV3/RGF4, GLV10/CLEL7/RGF5 and RGF10/CLELN), peptide hormones which maintain the postembryonic root stem cell niche by regulating the expression levels and patterns of the transcription factor PLETHORA (PLT, e.g. PLT1 and PLT2) (PubMed:27229312, PubMed:27229311, PubMed:27001831).

Links RGF peptides signal with their downstream components (PubMed:27229311, PubMed:27001831).

3 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei813ATPPROSITE-ProRule annotation1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei813Essential for autophosphorylation activityBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei920Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi791 – 799ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Receptor, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
LRR receptor-like serine/threonine-protein kinase RGI21 Publication (EC:2.7.11.1PROSITE-ProRule annotation)
Alternative name(s):
Protein RECEPTOR OF RGF1 31 Publication
Protein RGF1 INSENSITIVE 21 Publication
Protein ROOT CLAVATA-HOMOLOG1 11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RGI21 Publication
Synonyms:RCH11 Publication, RGFR22 Publications, RGFR31 Publication
Ordered Locus Names:At5g48940Imported
ORF Names:K19E20.5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT5G48940

The Arabidopsis Information Resource

More...
TAIRi
locus:2154344, AT5G48940

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini36 – 723ExtracellularSequence analysisAdd BLAST688
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei724 – 744HelicalSequence analysisAdd BLAST21
Topological domaini745 – 1135CytoplasmicSequence analysisAdd BLAST391

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Smaller root meristem size and fewer root meristematic cortex cells, associated with shorter roots and a slighty reduced sensitivity to RGF1 (PubMed:27229311). Quintuple mutants rgi1 rgi2 rgi3 rgi4 rgi5 display a consistent short primary root phenotype with a small size of meristem associated with a total insensitivity to RGF1 and undetectable levels of PLT1 and PLT2 (PubMed:27229312). The triple mutant missing RGI1, RGI2 and RGI3 is insensitive to externally applied RGF peptides (e.g. RGF1 and RGF2) and has short roots characterized by a strong decrease in meristematic cell number and declined levels of PLT1 and PLT2 at the root tip (PubMed:27001831).3 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 35Sequence analysisAdd BLAST35
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000038751836 – 1135LRR receptor-like serine/threonine-protein kinase RGI2Add BLAST1100

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi69 ↔ 76By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi101N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi117N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi273N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi345N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi358N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi369N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi444N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi465N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi492N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi502N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi521N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi524N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi598N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi618N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi665N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi707N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei777PhosphothreonineBy similarity1
Modified residuei868PhosphotyrosineBy similarity1
Modified residuei907PhosphotyrosineBy similarity1
Modified residuei963PhosphotyrosineBy similarity1
Modified residuei970PhosphotyrosineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated and ubiquitinated upon interaction with RGF1, thus leading to activation a subsequent degradation (By similarity). Stabilized by UBP12 and UBP13-mediated deubiquitination (By similarity).By similarity
Autophosphorylated.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
C0LGV1

PRoteomics IDEntifications database

More...
PRIDEi
C0LGV1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
225943

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Specific to root meristems, especially in lateral root meristems (LRM).4 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Present in the whole roots with a predominant expression in the proximal meristem, including the elongation zone, and a gradual decreases toward the differentiation zone.2 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
C0LGV1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
C0LGV1, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to RGF peptides such as RGF1, GLV5/CLEL1/RGF2, GLV7/CLEL3/RGF3, GLV3/RGF4, GLV10/CLEL7/RGF5 and RGF10/CLELN; these interactions trigger the formation of heterodimers with SERK1 (PubMed:27001831, PubMed:27229311).

Interacts with UBP13 (PubMed:29339500).

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
20198, 8 interactors

Protein interaction database and analysis system

More...
IntActi
C0LGV1, 9 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT5G48940.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
C0LGV1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati105 – 129LRR 1Sequence analysisAdd BLAST25
Repeati130 – 153LRR 2Sequence analysisAdd BLAST24
Repeati154 – 177LRR 3Sequence analysisAdd BLAST24
Repeati179 – 203LRR 4Sequence analysisAdd BLAST25
Repeati226 – 250LRR 5Sequence analysisAdd BLAST25
Repeati251 – 274LRR 6Sequence analysisAdd BLAST24
Repeati276 – 298LRR 7Sequence analysisAdd BLAST23
Repeati299 – 323LRR 8Sequence analysisAdd BLAST25
Repeati325 – 345LRR 9Sequence analysisAdd BLAST21
Repeati346 – 370LRR 10Sequence analysisAdd BLAST25
Repeati372 – 395LRR 11Sequence analysisAdd BLAST24
Repeati397 – 418LRR 12Sequence analysisAdd BLAST22
Repeati419 – 442LRR 13Sequence analysisAdd BLAST24
Repeati444 – 466LRR 14Sequence analysisAdd BLAST23
Repeati467 – 490LRR 15Sequence analysisAdd BLAST24
Repeati491 – 514LRR 16Sequence analysisAdd BLAST24
Repeati516 – 538LRR 17Sequence analysisAdd BLAST23
Repeati539 – 562LRR 18Sequence analysisAdd BLAST24
Repeati564 – 586LRR 19Sequence analysisAdd BLAST23
Repeati587 – 610LRR 20Sequence analysisAdd BLAST24
Repeati612 – 634LRR 21Sequence analysisAdd BLAST23
Repeati635 – 658LRR 22Sequence analysisAdd BLAST24
Repeati659 – 683LRR 23Sequence analysisAdd BLAST25
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini785 – 1066Protein kinasePROSITE-ProRule annotationAdd BLAST282

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1077 – 1135DisorderedSequence analysisAdd BLAST59

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi186 – 187Small peptide recognitionBy similarity2
Motifi208 – 211Small peptide recognitionBy similarity4
Motifi231 – 236Small peptide recognitionBy similarity6
Motifi259Small peptide recognitionBy similarity1
Motifi281 – 283Small peptide recognitionBy similarity3
Motifi329 – 332Small peptide recognitionBy similarity4
Motifi351 – 353Small peptide recognitionBy similarity3
Motifi399 – 403Small peptide recognitionBy similarity5
Motifi425 – 428Small peptide recognitionBy similarity4
Motifi447 – 451Small peptide recognitionBy similarity5
Motifi471 – 473Small peptide recognitionBy similarity3

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1095 – 1135Polar residuesSequence analysisAdd BLAST41

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QQEU, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000288_22_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
C0LGV1

Identification of Orthologs from Complete Genome Data

More...
OMAi
HERSGVC

Database of Orthologous Groups

More...
OrthoDBi
205337at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
C0LGV1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011009, Kinase-like_dom_sf
IPR001611, Leu-rich_rpt
IPR003591, Leu-rich_rpt_typical-subtyp
IPR032675, LRR_dom_sf
IPR013210, LRR_N_plant-typ
IPR000719, Prot_kinase_dom
IPR017441, Protein_kinase_ATP_BS
IPR001245, Ser-Thr/Tyr_kinase_cat_dom
IPR008271, Ser/Thr_kinase_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13855, LRR_8, 4 hits
PF08263, LRRNT_2, 1 hit
PF07714, PK_Tyr_Ser-Thr, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00369, LRR_TYP, 7 hits
SM00220, S_TKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56112, SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51450, LRR, 13 hits
PS00107, PROTEIN_KINASE_ATP, 1 hit
PS50011, PROTEIN_KINASE_DOM, 1 hit
PS00108, PROTEIN_KINASE_ST, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

C0LGV1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLQMPIPRK KALTVSHFSI TLSLFLAFFI SSTSASTNEV SALISWLHSS
60 70 80 90 100
NSPPPSVFSG WNPSDSDPCQ WPYITCSSSD NKLVTEINVV SVQLALPFPP
110 120 130 140 150
NISSFTSLQK LVISNTNLTG AISSEIGDCS ELIVIDLSSN SLVGEIPSSL
160 170 180 190 200
GKLKNLQELC LNSNGLTGKI PPELGDCVSL KNLEIFDNYL SENLPLELGK
210 220 230 240 250
ISTLESIRAG GNSELSGKIP EEIGNCRNLK VLGLAATKIS GSLPVSLGQL
260 270 280 290 300
SKLQSLSVYS TMLSGEIPKE LGNCSELINL FLYDNDLSGT LPKELGKLQN
310 320 330 340 350
LEKMLLWQNN LHGPIPEEIG FMKSLNAIDL SMNYFSGTIP KSFGNLSNLQ
360 370 380 390 400
ELMLSSNNIT GSIPSILSNC TKLVQFQIDA NQISGLIPPE IGLLKELNIF
410 420 430 440 450
LGWQNKLEGN IPDELAGCQN LQALDLSQNY LTGSLPAGLF QLRNLTKLLL
460 470 480 490 500
ISNAISGVIP LEIGNCTSLV RLRLVNNRIT GEIPKGIGFL QNLSFLDLSE
510 520 530 540 550
NNLSGPVPLE ISNCRQLQML NLSNNTLQGY LPLSLSSLTK LQVLDVSSND
560 570 580 590 600
LTGKIPDSLG HLISLNRLIL SKNSFNGEIP SSLGHCTNLQ LLDLSSNNIS
610 620 630 640 650
GTIPEELFDI QDLDIALNLS WNSLDGFIPE RISALNRLSV LDISHNMLSG
660 670 680 690 700
DLSALSGLEN LVSLNISHNR FSGYLPDSKV FRQLIGAEME GNNGLCSKGF
710 720 730 740 750
RSCFVSNSSQ LTTQRGVHSH RLRIAIGLLI SVTAVLAVLG VLAVIRAKQM
760 770 780 790 800
IRDDNDSETG ENLWTWQFTP FQKLNFTVEH VLKCLVEGNV IGKGCSGIVY
810 820 830 840 850
KAEMPNREVI AVKKLWPVTV PNLNEKTKSS GVRDSFSAEV KTLGSIRHKN
860 870 880 890 900
IVRFLGCCWN KNTRLLMYDY MSNGSLGSLL HERSGVCSLG WEVRYKIILG
910 920 930 940 950
AAQGLAYLHH DCVPPIVHRD IKANNILIGP DFEPYIGDFG LAKLVDDGDF
960 970 980 990 1000
ARSSNTIAGS YGYIAPEYGY SMKITEKSDV YSYGVVVLEV LTGKQPIDPT
1010 1020 1030 1040 1050
IPDGLHIVDW VKKIRDIQVI DQGLQARPES EVEEMMQTLG VALLCINPIP
1060 1070 1080 1090 1100
EDRPTMKDVA AMLSEICQER EESMKVDGCS GSCNNGRERG KDDSTSSVMQ
1110 1120 1130
QTAKYLRSSS TSFSASSLLY SSSSSATSNV RPNLK
Length:1,135
Mass (Da):123,612
Last modified:May 5, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE267BA44BAE0E69C
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB10317 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti79S → P in CAD79349 (PubMed:12932329).Curated1
Sequence conflicti257S → F in CAD79349 (PubMed:12932329).Curated1
Sequence conflicti369N → D in CAD79349 (PubMed:12932329).Curated1
Sequence conflicti463I → T in CAD79349 (PubMed:12932329).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ550162 mRNA Translation: CAD79349.1
AB017061 Genomic DNA Translation: BAB10317.1 Sequence problems.
CP002688 Genomic DNA Translation: AED95745.1
FJ708795 mRNA Translation: ACN59386.1

NCBI Reference Sequences

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RefSeqi
NP_199705.2, NM_124271.3

Genome annotation databases

Ensembl plant genome annotation project

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EnsemblPlantsi
AT5G48940.1; AT5G48940.1; AT5G48940

Database of genes from NCBI RefSeq genomes

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GeneIDi
834952

Gramene; a comparative resource for plants

More...
Gramenei
AT5G48940.1; AT5G48940.1; AT5G48940

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT5G48940

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ550162 mRNA Translation: CAD79349.1
AB017061 Genomic DNA Translation: BAB10317.1 Sequence problems.
CP002688 Genomic DNA Translation: AED95745.1
FJ708795 mRNA Translation: ACN59386.1
RefSeqiNP_199705.2, NM_124271.3

3D structure databases

SMRiC0LGV1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi20198, 8 interactors
IntActiC0LGV1, 9 interactors
STRINGi3702.AT5G48940.1

Proteomic databases

PaxDbiC0LGV1
PRIDEiC0LGV1
ProteomicsDBi225943

Genome annotation databases

EnsemblPlantsiAT5G48940.1; AT5G48940.1; AT5G48940
GeneIDi834952
GrameneiAT5G48940.1; AT5G48940.1; AT5G48940
KEGGiath:AT5G48940

Organism-specific databases

AraportiAT5G48940
TAIRilocus:2154344, AT5G48940

Phylogenomic databases

eggNOGiENOG502QQEU, Eukaryota
HOGENOMiCLU_000288_22_1_1
InParanoidiC0LGV1
OMAiHERSGVC
OrthoDBi205337at2759
PhylomeDBiC0LGV1

Miscellaneous databases

Protein Ontology

More...
PROi
PR:C0LGV1

Gene expression databases

ExpressionAtlasiC0LGV1, baseline and differential
GenevisibleiC0LGV1, AT

Family and domain databases

Gene3Di3.80.10.10, 4 hits
InterProiView protein in InterPro
IPR011009, Kinase-like_dom_sf
IPR001611, Leu-rich_rpt
IPR003591, Leu-rich_rpt_typical-subtyp
IPR032675, LRR_dom_sf
IPR013210, LRR_N_plant-typ
IPR000719, Prot_kinase_dom
IPR017441, Protein_kinase_ATP_BS
IPR001245, Ser-Thr/Tyr_kinase_cat_dom
IPR008271, Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF13855, LRR_8, 4 hits
PF08263, LRRNT_2, 1 hit
PF07714, PK_Tyr_Ser-Thr, 1 hit
SMARTiView protein in SMART
SM00369, LRR_TYP, 7 hits
SM00220, S_TKc, 1 hit
SUPFAMiSSF56112, SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51450, LRR, 13 hits
PS00107, PROTEIN_KINASE_ATP, 1 hit
PS50011, PROTEIN_KINASE_DOM, 1 hit
PS00108, PROTEIN_KINASE_ST, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRGI2_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C0LGV1
Secondary accession number(s): Q84RP6, Q9FI77
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: September 29, 2021
This is version 89 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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