UniProtKB - C0LGS3 (Y4372_ARATH)
Protein
Probable LRR receptor-like serine/threonine-protein kinase At4g37250
Gene
At4g37250
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Catalytic activityi
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- protein serine kinase activity Source: UniProtKB-EC
- protein threonine kinase activity Source: UniProtKB-EC
Keywordsi
Molecular function | Kinase, Receptor, Serine/threonine-protein kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:At4g37250 ORF Names:AP22.22, C7A10.110 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G37250 |
TAIRi | locus:2115120, AT4G37250 |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass type I membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 22 – 328 | ExtracellularSequence analysisAdd BLAST | 307 | |
Transmembranei | 329 – 349 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 350 – 768 | CytoplasmicSequence analysisAdd BLAST | 419 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 21 | Sequence analysisAdd BLAST | 21 | |
ChainiPRO_0000387558 | 22 – 768 | Probable LRR receptor-like serine/threonine-protein kinase At4g37250Add BLAST | 747 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 64 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 99 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 144 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 163 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 196 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 212 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 233 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 242 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 451 | PhosphoserineBy similarity | 1 | |
Modified residuei | 531 | PhosphoserineBy similarity | 1 | |
Modified residuei | 553 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 662 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
Glycoprotein, PhosphoproteinProteomic databases
PaxDbi | C0LGS3 |
PRIDEi | C0LGS3 |
ProteomicsDBi | 243127 |
PTM databases
iPTMneti | C0LGS3 |
Expressioni
Gene expression databases
ExpressionAtlasi | C0LGS3, baseline and differential |
Genevisiblei | C0LGS3, AT |
Interactioni
Binary interactionsi
Hide detailsC0LGS3
Protein-protein interaction databases
BioGRIDi | 15160, 38 interactors |
IntActi | C0LGS3, 43 interactors |
STRINGi | 3702.AT4G37250.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 67 – 90 | LRR 1Add BLAST | 24 | |
Repeati | 91 – 112 | LRR 2Add BLAST | 22 | |
Repeati | 115 – 137 | LRR 3Add BLAST | 23 | |
Repeati | 139 – 162 | LRR 4Add BLAST | 24 | |
Repeati | 163 – 183 | LRR 5Add BLAST | 21 | |
Repeati | 184 – 206 | LRR 6Add BLAST | 23 | |
Repeati | 207 – 229 | LRR 7Add BLAST | 23 | |
Repeati | 232 – 254 | LRR 8Add BLAST | 23 | |
Domaini | 449 – 756 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 308 |
Sequence similaritiesi
Keywords - Domaini
Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QRF8, Eukaryota |
HOGENOMi | CLU_000288_92_6_1 |
InParanoidi | C0LGS3 |
OMAi | GWRVVEF |
OrthoDBi | 486781at2759 |
PhylomeDBi | C0LGS3 |
Family and domain databases
Gene3Di | 3.80.10.10, 2 hits |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR001611, Leu-rich_rpt IPR032675, LRR_dom_sf IPR013210, LRR_N_plant-typ IPR000719, Prot_kinase_dom |
Pfami | View protein in Pfam PF00560, LRR_1, 1 hit PF13516, LRR_6, 1 hit PF08263, LRRNT_2, 1 hit PF00069, Pkinase, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
C0LGS3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRMELISVIF FFFCSVLSSS ALNSDGLVLM KFKSSVLVDP LSLLQTWNYK
60 70 80 90 100
HESPCSWRGI SCNNDSKVLT LSLPNSQLLG SIPSDLGSLL TLQSLDLSNN
110 120 130 140 150
SFNGPLPVSF FNARELRFLD LSSNMISGEI PSAIGDLHNL LTLNLSDNAL
160 170 180 190 200
AGKLPTNLAS LRNLTVVSLE NNYFSGEIPG GWRVVEFLDL SSNLINGSLP
210 220 230 240 250
PDFGGYSLQY LNVSFNQISG EIPPEIGVNF PRNVTVDLSF NNLTGPIPDS
260 270 280 290 300
PVFLNQESNF FSGNPGLCGE PTRNPCLIPS SPSIVSEADV PTSTPAIAAI
310 320 330 340 350
PNTIGSNPVT DPNSQQTDPN PRTGLRPGVI IGIVVGDIAG IGILAVIFLY
360 370 380 390 400
IYRCKKNKIV DNNNNDKQRT ETDTITLSTF SSSSSSPEES RRFRKWSCLR
410 420 430 440 450
KDPETTPSEE EDEDDEDEES GYNANQRSGD NKLVTVDGEK EMEIETLLKA
460 470 480 490 500
SAYILGATGS SIMYKAVLED GRVFAVRRLG ENGLSQRRFK DFEPHIRAIG
510 520 530 540 550
KLVHPNLVRL CGFYWGTDEK LVIYDFVPNG SLVNPRYRKG GGSSSPYHLP
560 570 580 590 600
WETRLKIAKG IARGLAYLHE KKHVHGNLKP SNILLGHDME PKIGDFGLER
610 620 630 640 650
LLTGETSYIR AGGSSRIFSS KRYTTSSREF SSIGPTPSPS PSSVGAMSPY
660 670 680 690 700
CAPESFRSLK PSPKWDVYGF GVILLELLTG KIVSVEEIVL GNGLTVEDGH
710 720 730 740 750
RAVRMADVAI RGELDGKQEF LLDCFKLGYS CASPVPQKRP TMKESLAVLE
760
RFHPNSSVIK SSSFHYGH
Sequence cautioni
The sequence CAB16774 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAB80391 differs from that shown. Reason: Erroneous initiation.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 361 | D → Y in AAN72248 (PubMed:14593172).Curated | 1 | |
Sequence conflicti | 361 | D → Y in AAL57701 (PubMed:14593172).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z99707 Genomic DNA Translation: CAB16774.1 Different initiation. AL161591 Genomic DNA Translation: CAB80391.1 Different initiation. CP002687 Genomic DNA Translation: AEE86773.1 AY065068 mRNA Translation: AAL57701.1 BT002237 mRNA Translation: AAN72248.1 FJ708765 mRNA Translation: ACN59358.1 AK317633 mRNA Translation: BAH20295.1 |
PIRi | B85440 |
RefSeqi | NP_195442.2, NM_119888.3 |
Genome annotation databases
EnsemblPlantsi | AT4G37250.1; AT4G37250.1; AT4G37250 |
GeneIDi | 829879 |
Gramenei | AT4G37250.1; AT4G37250.1; AT4G37250 |
KEGGi | ath:AT4G37250 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z99707 Genomic DNA Translation: CAB16774.1 Different initiation. AL161591 Genomic DNA Translation: CAB80391.1 Different initiation. CP002687 Genomic DNA Translation: AEE86773.1 AY065068 mRNA Translation: AAL57701.1 BT002237 mRNA Translation: AAN72248.1 FJ708765 mRNA Translation: ACN59358.1 AK317633 mRNA Translation: BAH20295.1 |
PIRi | B85440 |
RefSeqi | NP_195442.2, NM_119888.3 |
3D structure databases
SMRi | C0LGS3 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 15160, 38 interactors |
IntActi | C0LGS3, 43 interactors |
STRINGi | 3702.AT4G37250.1 |
PTM databases
iPTMneti | C0LGS3 |
Proteomic databases
PaxDbi | C0LGS3 |
PRIDEi | C0LGS3 |
ProteomicsDBi | 243127 |
Genome annotation databases
EnsemblPlantsi | AT4G37250.1; AT4G37250.1; AT4G37250 |
GeneIDi | 829879 |
Gramenei | AT4G37250.1; AT4G37250.1; AT4G37250 |
KEGGi | ath:AT4G37250 |
Organism-specific databases
Araporti | AT4G37250 |
TAIRi | locus:2115120, AT4G37250 |
Phylogenomic databases
eggNOGi | ENOG502QRF8, Eukaryota |
HOGENOMi | CLU_000288_92_6_1 |
InParanoidi | C0LGS3 |
OMAi | GWRVVEF |
OrthoDBi | 486781at2759 |
PhylomeDBi | C0LGS3 |
Miscellaneous databases
PROi | PR:C0LGS3 |
Gene expression databases
ExpressionAtlasi | C0LGS3, baseline and differential |
Genevisiblei | C0LGS3, AT |
Family and domain databases
Gene3Di | 3.80.10.10, 2 hits |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR001611, Leu-rich_rpt IPR032675, LRR_dom_sf IPR013210, LRR_N_plant-typ IPR000719, Prot_kinase_dom |
Pfami | View protein in Pfam PF00560, LRR_1, 1 hit PF13516, LRR_6, 1 hit PF08263, LRRNT_2, 1 hit PF00069, Pkinase, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Y4372_ARATH | |
Accessioni | C0LGS3Primary (citable) accession number: C0LGS3 Secondary accession number(s): B9DHS8, O23161, Q8VZC5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 3, 2009 |
Last sequence update: | May 5, 2009 | |
Last modified: | February 10, 2021 | |
This is version 86 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families