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1 to 25 of 139  Show
  1. 1
    "Multiple isoforms of PAX5 are expressed in both lymphomas and normal B-cells."
    Arseneau J.R., Laflamme M., Lewis S.M., Maicas E., Ouellette R.J.
    Br. J. Haematol. 147:328-338(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).

    This publication is cited by 14 other entries.

  2. 2
    Arseneau J.-R., Laflamme M., Lewis S.M., Maicas E., Ouellette R.J.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).
  3. 3
    "The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells."
    Emelyanov A.V., Kovac C.R., Sepulveda M.A., Birshtein B.K.
    J. Biol. Chem. 277:11156-11164(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: interaction with Daxx resulting in transcriptional activation in B cells.
    Source: GeneRIF:5079.

    This publication is cited by 1 and mapped to 74 other entries.

  4. 4
    "The heterogeneity shown by human plasma cells from tonsil, blood, and bone marrow reveals graded stages of increasing maturity, but local profiles of adhesion molecule expression."
    Medina F., Segundo C., Campos-Caro A., Gonzalez-Garcia I., Brieva J.A.
    Blood 99:2154-2161(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: were expressed by human PCs following a gradient of increasing maturity in the direction: tonsil-->blood-->BM.
    Source: GeneRIF:5079.

    This publication is mapped to 28 other entries.

  5. 5
    "Altered mRNA expression of Pax5 and Blimp-1 in B cells in multiple myeloma."
    Borson N.D., Lacy M.Q., Wettstein P.J.
    Blood 100:4629-4639(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: Multiple isoforms of Pax5 & low levels of the full-length Pax5 were seen in B cells from MM patients. Premature Blimp-1 expression & altered deficient Pax5 expression causes some proliferating B cells to prematurely differentiate to plasma cells.
    Source: GeneRIF:5079.

    This publication is mapped to 28 other entries.

  6. 6
    "[Expression and significance of B-cell-specific activator protein of H/RS cell in classical Hodgkin's Lymphoma]."
    Zhou X., Zhao T., Qi Z., Liu G., Zhu M.
    Zhonghua Yi Xue Za Zhi 82:1532-1535(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: The frequent expression of B-cell-specific activator protein (BSAP)in Reed-Sternberg (H/RS) cells of classical Hodgkin's disease provides further evidence for its B-cell origin and helps to identify H/RS cells.
    Source: GeneRIF:5079.

    This publication is mapped to 20 other entries.

  7. 7
    "Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site."
    Maier H., Colbert J., Fitzsimmons D., Clark D.R., Hagman J.
    Mol Cell Biol 23:1946-1960(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Retrovirally expressed human Pax-5 protein activates endogenous early B-cell-specific mb-1 genes in mouse plasmacytoma cells but only when the promoter is hypomethylated.
    Source: GeneRIF:5079.

    This publication is mapped to 21 other entries.

  8. 8
    "Pax-5 is a key regulator of the B cell-restricted expression of the CD23a isoform."
    Visan I., Goller M., Berberich I., Kneitz C., Tony H.P.
    Eur J Immunol 33:1163-1173(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: Pax-5 is a key regulator of the B-cell-restricted expression of the CD23a isoform.
    Source: GeneRIF:5079.

    This publication is mapped to 24 other entries.

  9. 9
    "Human Pax-5 C-terminal isoforms possess distinct transactivation properties and are differentially modulated in normal and malignant B cells."
    Robichaud G.A., Nardini M., Laflamme M., Cuperlovic-Culf M., Ouellette R.J.
    J. Biol. Chem. 279:49956-49963(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Isoform expression is modulated by specific signaling pathways in B lymphocytes.
    Source: GeneRIF:5079.

    This publication is mapped to 19 other entries.

  10. 10
    "PAX5 expression in acute leukemias: higher B-lineage specificity than CD79a and selective association with t(8;21)-acute myelogenous leukemia."
    Tiacci E., Pileri S., Orleth A., Pacini R., Tabarrini A., Frenguelli F., Liso A., Diverio D., Lo-Coco F., Falini B.
    Cancer Res 64:7399-7404(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Expression.
    Annotation: Results indicate that PAX5 is a more specific marker than CD79a for B-cell ALL diagnosis.
    Source: GeneRIF:5079.

    This publication is mapped to 21 other entries.

  11. 11
    "Expression of mRNA for a newly identified Pax5 exon is reduced in multiple myeloma."
    Borson N.D., Lacy M.Q., Wettstein P.J.
    Mamm Genome 17:248-256(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Expression of mRNA for a newly identified Pax5 exon is reduced in multiple myeloma.
    Source: GeneRIF:5079.

    This publication is mapped to 20 other entries.

  12. 12
    "Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation."
    Reiniger L., Bodor C., Bognar A., Balogh Z., Csomor J., Szepesi A., Kopper L., Matolcsy A.
    Leukemia 20:1089-1095(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: In both Richter's transformation and prolymphocytic transformation high-levels of AID mRNA expression and high-frequency mutations of Pax-5 protein genes were detected.
    Source: GeneRIF:5079.

    This publication is mapped to 102 other entries.

  13. 13
    "Transcription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genes."
    Zhang Z., Espinoza C.R., Yu Z., Stephan R., He T., Williams G.S., Burrows P.D., Hagman J., Feeney A.J., Cooper M.D.
    Nat Immunol 7:616-624(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: These findings indicate a direct activating function for Pax5 in RAG-mediated immunoglobulin V(H)-to-DJ(H) recombination.
    Source: GeneRIF:5079.

    This publication is mapped to 39 other entries.

  14. 14
    Category: Expression, Sequences.
    Annotation: Results confirm that Pax-5 is expressed regularly in poorly differentiated neuroendocrine tumors.
    Source: GeneRIF:5079.

    This publication is mapped to 20 other entries.

  15. 15
    "Pax5 maintains cellular identity by repressing gene expression throughout B cell differentiation."
    Carotta S., Holmes M.L., Pridans C., Nutt S.L.
    Cell Cycle 5:2452-2456(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Expression.
    Annotation: Pax5 maintains cellular identity by repressing gene expression throughout B cell differentiation (review).
    Source: GeneRIF:5079.

    This publication is mapped to 20 other entries.

  16. 16
    "Rare expression of BSAP (PAX-5) in mature T-cell lymphomas."
    Tzankov A.S., Went P.T., Munst S., Papadopoulos T., Jundt G., Dirnhofer S.R.
    Mod Pathol 20:632-637(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: BSAP can probably contribute to T-cell lymphomagenesis not only in vitro but also in vivo. It is rarely expressed in peripheral T-cell lymphoma thus its detection on lymphoid malignancies cannot be considered definitively lineage specific.
    Source: GeneRIF:5079.

    This publication is mapped to 20 other entries.

  17. 17
    "Analysis of BCL-6, CD95, PIM1, RHO/TTF and PAX5 mutations in splenic and nodal marginal zone B-cell lymphomas suggests a particular B-cell origin."
    Traverse-Glehen A., Verney A., Baseggio L., Felman P., Callet-Bauchu E., Thieblemont C., Ffrench M., Magaud J.P., Coiffier B., Berger F., Salles G.
    Leukemia 21:1821-1824(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PAX5 mutation is associated with splenic and nodal marginal zone B-cell lymphomas.
    Source: GeneRIF:5079.

    This publication is mapped to 26 other entries.

  18. 18
    "The utility of PAX5 immunohistochemistry in the diagnosis of undifferentiated malignant neoplasms."
    Jensen K.C., Higgins J.P., Montgomery K., Kaygusuz G., van de Rijn M., Natkunam Y.
    Mod Pathol 20:871-877(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: PAX5 is a useful immunohistologic marker for the interrogation of undifferentiated neoplasms. It is an extremely specific marker of the B lineage.
    Source: GeneRIF:5079.

    This publication is mapped to 20 other entries.

  19. 19
    Category: Sequences.
    Annotation: PAX5 was identified as a useful tumor marker for the diagnosis of pediatric large cell lymphoma.
    Source: GeneRIF:5079.

    This publication is mapped to 28 other entries.

  20. 20
    "Epstein-Barr virus exploits BSAP/Pax5 to achieve the B-cell specificity of its growth-transforming program."
    Tierney R., Nagra J., Hutchings I., Shannon-Lowe C., Altmann M., Hammerschmidt W., Rickinson A., Bell A.
    J Virol 81:10092-10100(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: EBV ensures the B-cell specificity of its growth-transforming function by exploiting BSAP/Pax5 as a lineage-specific activator of the transforming program.
    Source: GeneRIF:5079.

    This publication is mapped to 20 other entries.

  21. 21
    "Biphenotypic bigenotypic lymphoma with simultaneous expression of PAX5/BSAP and B- and T-cell markers."
    Hansson M., Jerkeman M., Dictor M.
    Eur J Haematol 79:159-165(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Simultaneous nuclear expression of the transcription factor gene PAX5 suggested that this major driver of B-cell differentiation did not preclude expression of CD3epsilon.
    Source: GeneRIF:5079.

    This publication is mapped to 20 other entries.

  22. 22
    "Human BSAP and BLIMP1 conform an autoregulatory feedback loop."
    Mora-Lopez F., Reales E., Brieva J.A., Campos-Caro A.
    Blood 110:3150-3157(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Interaction.
    Annotation: Repression of PRDM1 by BSAP reveals an autoregulatory negative-feedback loop that could play a relevant role in controlling human PC differentiation.
    Source: GeneRIF:5079.

    This publication is mapped to 28 other entries.

  23. 23
    Category: Function.
    Annotation: stimulation of neoplastic growth by Pax5 occurs through B cell receptor and is sensitive to genetic and pharmacological inhibitors of this pathway.
    Source: GeneRIF:5079.

    This publication is mapped to 24 other entries.

  24. 24
    "Transcription factors Xbp-1, Blimp-1, and BSAP are involved in the regulation of plasmacytic differentiation induced by 2-methoxyestradiol in myeloma cell lines."
    Jiang H., Gao W., Sze D.M., Xiong H., Hou J.
    Int J Hematol 86:429-437(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: that transcription factors Xbp-1 Blimp-1 and PAX-5-encoded BSAP play important roles in the regulation of plasmacytic differentiation and exert their effects on differentiation induced by low 2ME2 concentrations.
    Source: GeneRIF:5079.

    This publication is mapped to 31 other entries.

  25. 25
    "PAX-5 expression in pulmonary neuroendocrine neoplasms: its usefulness in surgical and fine-needle aspiration biopsy specimens."
    Sica G., Vazquez M.F., Altorki N., Port J., Lee P.C., Liu Y., Hyjek E., Saqi A.
    Am J Clin Pathol 129:556-562(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: PAX-5 is a useful marker for the discrimination of low- to intermediate-grade pulmonary neuroendocrine neoplasms from high-grade ones.
    Source: GeneRIF:5079.

    This publication is mapped to 20 other entries.

1 to 25 of 139  Show
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