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Protein
Submitted name:

DNA helicase, putative

Gene

PF3D7_0818700

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
DNA helicase, putativeImported (EC:3.6.4.12Imported)
Gene namesi
ORF Names:PF3D7_0818700Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0818700

PTM / Processingi

Proteomic databases

PRIDEiC0H4V8

Structurei

3D structure databases

ProteinModelPortaliC0H4V8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini220 – 425Helicase ATP-bindingInterPro annotationAdd BLAST206
Domaini1038 – 1217Helicase C-terminalInterPro annotationAdd BLAST180

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili98 – 125Sequence analysisAdd BLAST28
Coiled coili681 – 701Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000282661
InParanoidiC0H4V8

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR037780 CHD1
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PANTHERiPTHR10799:SF838 PTHR10799:SF838, 2 hits
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 6 hits
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

Sequencei

Sequence statusi: Complete.

C0H4V8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDVFEFVDPL RKRKINNNIL DFNKYVYKDK MEVGEEEIEH DEEKTKDDEI
60 70 80 90 100
INMKKKKKKK KKKKLRRLLD SSSSDDNNEN EEISSKKIKI RKLNSDNEDN
110 120 130 140 150
KLKNNNNEKK KKEKVEDEKQ SNDIEILDSY DEDDENQKAE YEYNLNTLYQ
160 170 180 190 200
CLYISIQIKN RIIDHFTSEK KDKKEELIKE FVKGSFRVSN FQANYEDFEK
210 220 230 240 250
YVDTFHKLKC YQKCGVLWLY VLYKQNKNGI LADEMGLGKT AQTCVFLDYM
260 270 280 290 300
YKTGTIKNKT IIVAPTSLLK NWDNEINMWC PYLRNHKIIY YGSQSERRYL
310 320 330 340 350
AYDIFSSKGS KNNKYFPSNN NDDEDDGVNN NNNNNNNDDG HNNIHLIITS
360 370 380 390 400
INMLMGKNDV SYFRQIKKYD YLIFDEAHFL KNKNSLIYKK LQKKIVFNNK
410 420 430 440 450
ILLTGSPIQN KTQELTNLLL FLMPHIFTET NINNAMQAFI AMYEEEVQTR
460 470 480 490 500
NKKKKMDEGT TPKLTTFVEE IMKKNETQSN NNNNNNNNNN NSNNNSNNSN
510 520 530 540 550
NNSNNNNNNS NNNNNSSNNI MMDKCSDMCH KLTDDNNSMN NNYNIYDIKC
560 570 580 590 600
DEEVTDGNIK DDNEKDNNVI VSDTNKSIIK NYLIQTIRDD LKQHVELKNK
610 620 630 640 650
EIILLQLIIE PYILRRSKKH VFIDMPKKHS LIIKLPLNNT QLNLYKDEIF
660 670 680 690 700
SKMQKTFKHL EFLETHSSKK ELQKIYAILN KKEIKNEKNN TRVEKKEIQQ
710 720 730 740 750
NVDKENYQNG HCNNNTNNME SADHNVDVDI GHDNVHVHDD DDDDREMDEE
760 770 780 790 800
TINIEKTDEE NKNSNIVIHK RDDDSNDMDE DNIKDDNNSN SNSHNNNNMC
810 820 830 840 850
EDSTSPTKEV TLNKSKKNQE NNKNNKEVRG KMINASIFIL RRICNHPLLH
860 870 880 890 900
KYYYTVEDIK KISKYFYYNT DQYVDLDLKT VENEFMKISD FDIHLSIKHL
910 920 930 940 950
ISQGDNKLNK YLITKEHILN SSKINHMLSL IKDIRKKKEK VLIFSQFTTF
960 970 980 990 1000
LDIIEEALLY EFIYDDSDYM DHIQTIKSSQ SINKNDTICK EENNINVNVF
1010 1020 1030 1040 1050
IKEEQNYHDI GKETKRHDDN NNNNINDGDE NKFCFKENIK KPNDIYNEDM
1060 1070 1080 1090 1100
ENSERTKDTN CEYNKKKKDE DDEEICLTSS TLSTSSVGTQ NDAGHQIYVR
1110 1120 1130 1140 1150
LDGSTNTIER QKIIKRFSKD ENIFVFLLST KAGGVGLNLI AANHVILMDQ
1160 1170 1180 1190 1200
DWNPHNDRQA EDRVHRLGQK NEVFIYRLCC KNTIEEAILK CNKAKLHLDQ
1210 1220
AFGGNNELLQ TALIKDALNA VDI
Length:1,223
Mass (Da):143,663
Last modified:June 8, 2016 - v2
Checksum:i8629F5CA0F862898
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844507 Genomic DNA Translation: CAX64136.2

Genome annotation databases

EnsemblProtistsiCAX64136; CAX64136; PF3D7_0818700
GeneDBiPF3D7_0818700.1:pep

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844507 Genomic DNA Translation: CAX64136.2

3D structure databases

ProteinModelPortaliC0H4V8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiC0H4V8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCAX64136; CAX64136; PF3D7_0818700
GeneDBiPF3D7_0818700.1:pep

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0818700

Phylogenomic databases

HOGENOMiHOG000282661
InParanoidiC0H4V8

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR037780 CHD1
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PANTHERiPTHR10799:SF838 PTHR10799:SF838, 2 hits
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 6 hits
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC0H4V8_PLAF7
AccessioniPrimary (citable) accession number: C0H4V8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: June 8, 2016
Last modified: July 18, 2018
This is version 62 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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