UniProtKB - C0H3X4 (YEZG_BACSU)
Protein
Probable antitoxin YezG
Gene
yezG
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Probable antitoxin component of a type II toxin-antitoxin (TA) system. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable).Curated
Keywordsi
Biological process | Toxin-antitoxin system |
Enzyme and pathway databases
BioCyci | BSUB:BSU06811-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Probable antitoxin YezG |
Gene namesi | Name:yezG Synonyms:yeeE Ordered Locus Names:BSU06811 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000389483 | 1 – 151 | Probable antitoxin YezGAdd BLAST | 151 |
Proteomic databases
PRIDEi | C0H3X4 |
Interactioni
Subunit structurei
Interacts with probable cognate toxin YeeF but not with non-cognate toxin YobL. The interaction probably inhibits the toxic activity of YeeF.
1 PublicationProtein-protein interaction databases
IntActi | C0H3X4, 1 interactor |
MINTi | C0H3X4 |
STRINGi | 224308.BSU06811 |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 62 – 90 | Sequence analysisAdd BLAST | 29 |
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | ENOG5032YNG, Bacteria |
OMAi | YMNISRD |
PhylomeDBi | C0H3X4 |
Family and domain databases
InterProi | View protein in InterPro IPR006728, EsaG-like IPR036170, Prob_YezG_sf |
Pfami | View protein in Pfam PF04634, DUF600, 1 hit |
SUPFAMi | SSF160424, SSF160424, 1 hit |
TIGRFAMsi | TIGR01741, staph_tand_hypo, 1 hit |
i Sequence
Sequence statusi: Complete.
C0H3X4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQDLYQLIGE KLNDIIPGEW TKIYLYAEVL DDSTMVLFHF RTPENNQIIY
60 70 80 90 100
SQDIPSHYNV SKDIFKTLLR ELRELFEELR TEHRNNNDDV WTNLTLTLDR
110 120 130 140 150
SGEFQLDYNY DDILASELDG YERIAIWEYK NLGILPEDED DKEFVISYLG
L
Sequence cautioni
The sequence AAB66478 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF012532 Genomic DNA Translation: AAB66478.1 Different initiation. AL009126 Genomic DNA Translation: CAX52579.1 |
RefSeqi | WP_010886434.1, NZ_JNCM01000032.1 YP_003097692.1, NC_000964.3 |
Genome annotation databases
EnsemblBacteriai | CAX52579; CAX52579; BSU06811 |
GeneIDi | 8303066 |
KEGGi | bsu:BSU06811 |
PATRICi | fig|224308.43.peg.718 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF012532 Genomic DNA Translation: AAB66478.1 Different initiation. AL009126 Genomic DNA Translation: CAX52579.1 |
RefSeqi | WP_010886434.1, NZ_JNCM01000032.1 YP_003097692.1, NC_000964.3 |
3D structure databases
SMRi | C0H3X4 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | C0H3X4, 1 interactor |
MINTi | C0H3X4 |
STRINGi | 224308.BSU06811 |
Proteomic databases
PRIDEi | C0H3X4 |
Genome annotation databases
EnsemblBacteriai | CAX52579; CAX52579; BSU06811 |
GeneIDi | 8303066 |
KEGGi | bsu:BSU06811 |
PATRICi | fig|224308.43.peg.718 |
Phylogenomic databases
eggNOGi | ENOG5032YNG, Bacteria |
OMAi | YMNISRD |
PhylomeDBi | C0H3X4 |
Enzyme and pathway databases
BioCyci | BSUB:BSU06811-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR006728, EsaG-like IPR036170, Prob_YezG_sf |
Pfami | View protein in Pfam PF04634, DUF600, 1 hit |
SUPFAMi | SSF160424, SSF160424, 1 hit |
TIGRFAMsi | TIGR01741, staph_tand_hypo, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YEZG_BACSU | |
Accessioni | C0H3X4Primary (citable) accession number: C0H3X4 Secondary accession number(s): O30580 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 24, 2009 |
Last sequence update: | May 5, 2009 | |
Last modified: | December 2, 2020 | |
This is version 57 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |