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Protein

DNA polymerase I

Gene

polA

Organism
Borreliella spielmanii A14S
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, DNA-directed DNA polymeraseUniRule annotation, Hydrolase, NucleaseSAAS annotation, Nucleotidyltransferase, Transferase
Biological processDNA damage, DNA repairUniRule annotation, DNA replicationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase IUniRule annotation (EC:2.7.7.7UniRule annotation)
Gene namesi
Name:polAUniRule annotationImported
ORF Names:BSPA14S_0557Imported
OrganismiBorreliella spielmanii A14SImported
Taxonomic identifieri498742 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000003481 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi498742.BSPA14S_0557

Structurei

3D structure databases

ProteinModelPortaliB9X8G2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 25953EXOcInterPro annotationAdd BLAST259
Domaini321 – 5003'-5' exonucleaseInterPro annotationAdd BLAST180
Domaini666 – 872POLAcInterPro annotationAdd BLAST207

Sequence similaritiesi

Belongs to the DNA polymerase type-A family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C2M Bacteria
COG0258 LUCA
COG0749 LUCA
OrthoDBiPOG091H00PR

Family and domain databases

CDDicd09898 H3TH_53EXO, 1 hit
Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR002562 3'-5'_exonuclease_dom
IPR020046 5-3_exonucl_a-hlix_arch_N
IPR036279 5-3_exonuclease_C_sf
IPR002421 5-3_exonuclease_N
IPR019760 DNA-dir_DNA_pol_A_CS
IPR001098 DNA-dir_DNA_pol_A_palm_dom
IPR020045 DNA_polI_H3TH
IPR018320 DNA_polymerase_1
IPR002298 DNA_polymerase_A
IPR008918 HhH2
IPR029060 PIN-like_dom_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PANTHERiPTHR10133 PTHR10133, 1 hit
PfamiView protein in Pfam
PF01367 5_3_exonuc, 1 hit
PF02739 5_3_exonuc_N, 1 hit
PF00476 DNA_pol_A, 1 hit
PF01612 DNA_pol_A_exo1, 1 hit
PRINTSiPR00868 DNAPOLI
SMARTiView protein in SMART
SM00474 35EXOc, 1 hit
SM00475 53EXOc, 1 hit
SM00279 HhH2, 1 hit
SM00482 POLAc, 1 hit
SUPFAMiSSF47807 SSF47807, 1 hit
SSF53098 SSF53098, 1 hit
SSF88723 SSF88723, 1 hit
TIGRFAMsiTIGR00593 pola, 1 hit
PROSITEiView protein in PROSITE
PS00447 DNA_POLYMERASE_A, 1 hit

Sequencei

Sequence statusi: Complete.

B9X8G2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKELYLIDAL NIIFRNYHVM KNYPLLNTQG ENVNAFVGFF KTLFFIIKEK
60 70 80 90 100
NPKHLIITFD SEIPTFRKQK YPNYKATRDA PPDDLIPQIG WIKKGLLKAK
110 120 130 140 150
IPIFEIEGYE ADDLLASFAK KATQNNYLTY IISPDKDLLQ IMSEHIKILK
160 170 180 190 200
IENNRFVEMD NEYVIKKFGI NSFQIKDYLA IVGDRSDNIP GIKGIGPKGA
210 220 230 240 250
ANLLREFKTL KGIYSNLELI TKKHQEILIK EKENAFLSYD LVSLEENLKI
260 270 280 290 300
PEIENFALKN FSEEIISLFE KHSAITLIKT YKRDILKQEE ENLAQKSLFK
310 320 330 340 350
QESTTKSIDT LNTIDTENVK YHSITTKKEL DNLIESLKKA KYISIDTETS
360 370 380 390 400
SLDIYTARLI GISISFKEFE GYYIPIEARG KIYIEKHYII QKFNNFFESN
410 420 430 440 450
PKIIGQNYKF DYKILKNNGF NPIPPYFDTM IAAYLIDTNS KVSLDFLAEK
460 470 480 490 500
YLMHKNIKYE DVIQKNDNFA GISLEMATSY SSEDADITFR LFNVFSKKLK
510 520 530 540 550
EDSLDKLMHE IEMPFNNVII EMEENGIYLD REYLKEYGKE LGKELELIET
560 570 580 590 600
EIIKSIGIDF NLNSPKQMHE ILFEKLNLKL PEKMKKDSTD IKVLESLRGQ
610 620 630 640 650
HESIENLIKH RQIAKLKSTY TDNLIELINY KTNRLHTNFI QTKTATGRVT
660 670 680 690 700
SINPNLQNIP IKDEKGRKIR KAFKPENGNI FISADYSQIE LAILAHLSQD
710 720 730 740 750
EVLIKAFENN KDIHTETASK LFKIEEKEIT PNLRRIAKSI NFGIIYRMSD
760 770 780 790 800
FRLAKELGIT KEEAKGFIDS YFDSYPKIKE FIINQINFVR NTGYSETILK
810 820 830 840 850
RRRYIKEINS NNYLERSAAE RISINSIIQG SAADIMKIAM VKVFNEFKSK
860 870 880 890 900
KMESKILLQV HDEMLIESPI KEENEVKKIL KIMMETAYTL TPPLRANIET

GKSWGEIH
Length:908
Mass (Da):105,580
Last modified:April 14, 2009 - v1
Checksum:iDE5F5BF1EBE89882
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABKB02000009 Genomic DNA Translation: EEF84232.1
RefSeqiWP_006433865.1, NZ_ABKB02000009.1

Genome annotation databases

EnsemblBacteriaiEEF84232; EEF84232; BSPA14S_0557

Similar proteinsi

Entry informationi

Entry nameiB9X8G2_9SPIR
AccessioniPrimary (citable) accession number: B9X8G2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 14, 2009
Last sequence update: April 14, 2009
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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