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Protein

Mitochondrial import inner membrane translocase subunit TIM44

Gene

Cd36_80220

Organism
Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) (Yeast)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, TranslocationUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial import inner membrane translocase subunit TIM44UniRule annotation
Gene namesi
Ordered Locus Names:Cd36_80220Imported
ORF Names:CD36_80220Imported
OrganismiCandida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) (Yeast)Imported
Taxonomic identifieri573826 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000002605 Componenti: Chromosome 3

Organism-specific databases

CGDiCAL0000164286 Cd36_80220

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi573826.XP_002418970.1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini265 – 419Tim44InterPro annotationAdd BLAST155

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili50 – 77Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the Tim44 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2580 Eukaryota
ENOG410Y5IK LUCA
HOGENOMiHOG000208172
KOiK17804
OrthoDBiEOG092C2GAN

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit

Sequencei

Sequence statusi: Complete.

B9WD03-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRSGIIKKQ PATAIIRPLI SARCFHYTNV NLNDKPPSSD SPLKVFFDTF
60 70 80 90 100
KTEVKKSNEL KENIKALQDE SGRMAESEAF KRAKEAYAKA QLGSTAAGKV
110 120 130 140 150
LKKGAETVGD AAYKAWESPV GKGVRTSVRV TADVADKAFE PVRKTQVYKD
160 170 180 190 200
MSEVIDDGSS TAYGGFLTKE QREALRKKEL ERKKKQGFQG PVKENEEAGG
210 220 230 240 250
ALVATEHKAT GPTVGEKWEN FKLKSPIGRG VVYLQEKWEE SENGLIALIR
260 270 280 290 300
TIVEKVTGFF SETEQAKVVK QLKLMDPSFR LTDFQRTLTN YIVPEVVDAY
310 320 330 340 350
IKNDAKVLKE WLSEAPYNVW EANNKQFIQQ GLFSDSRVLD IRGVDIVTCK
360 370 380 390 400
SLQPNDVPVI VVSCRAQEIH LYRKAKTGEI AAGTEDHIQL STYAMVLTRI
410 420
PEEFDNKVTD GWKIVEFARG GSRPFH
Length:426
Mass (Da):47,657
Last modified:March 24, 2009 - v1
Checksum:i1E176804576FB08E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM992690 Genomic DNA Translation: CAX42552.1
RefSeqiXP_002418970.1, XM_002418925.1

Genome annotation databases

EnsemblFungiiCAX42552; CAX42552; CD36_80220
GeneIDi8046752
KEGGicdu:CD36_80220

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM992690 Genomic DNA Translation: CAX42552.1
RefSeqiXP_002418970.1, XM_002418925.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi573826.XP_002418970.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAX42552; CAX42552; CD36_80220
GeneIDi8046752
KEGGicdu:CD36_80220

Organism-specific databases

CGDiCAL0000164286 Cd36_80220

Phylogenomic databases

eggNOGiKOG2580 Eukaryota
ENOG410Y5IK LUCA
HOGENOMiHOG000208172
KOiK17804
OrthoDBiEOG092C2GAN

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB9WD03_CANDC
AccessioniPrimary (citable) accession number: B9WD03
Entry historyiIntegrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: November 7, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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