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Entry version 49 (05 Jun 2019)
Sequence version 1 (24 Mar 2009)
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Protein
Submitted name:

Spike-1, putative

Gene

RCOM_1244720

Organism
Ricinus communis (Castor bean)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Spike-1, putativeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:RCOM_1244720Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRicinus communis (Castor bean)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3988 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesEuphorbiaceaeAcalyphoideaeAcalypheaeRicinus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3988.XP_002516704.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini476 – 635DHR-1InterPro annotationAdd BLAST160
Domaini1393 – 1842DHR-2InterPro annotationAdd BLAST450

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni295 – 316DisorderedSequence analysisAdd BLAST22
Regioni378 – 453DisorderedSequence analysisAdd BLAST76

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi389 – 450PolarSequence analysisAdd BLAST62

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DOCK family.PROSITE-ProRule annotation

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
B9RSI5

KEGG Orthology (KO)

More...
KOi
K21852

Database of Orthologous Groups

More...
OrthoDBi
20156at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR027007 DHR-1_domain
IPR027357 DHR-2
IPR026791 DOCK
IPR010703 DOCK_C

The PANTHER Classification System

More...
PANTHERi
PTHR23317 PTHR23317, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06920 DHR-2, 1 hit
PF14429 DOCK-C2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51650 DHR_1, 1 hit
PS51651 DHR_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B9RSI5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENSGSSSGG QRFRRIPRQS LASLKLDPLL DENLDQWPHL NELVQCYRTD
60 70 80 90 100
WVKDETKYGH FESIASVSFQ NQIFEGPDTD IETEMQLANS RQAKAEDITF
110 120 130 140 150
DDIPSTSGRQ FVDDLSQPHV SKHFGHSPLP AYEPAFDWEN ERSMIFGQRI
160 170 180 190 200
PETAMAPFGR GLKISVKVLS LSFQAGLVEP FYGTICIYNK ERREKLSEDF
210 220 230 240 250
YFSVVPTDTQ DARISHEPHV IFYLDAPSAS ICLLIQLEKP ATEEGGVTPS
260 270 280 290 300
VYSRKEPVHL SEREKQKLQV WSRIMPYRQS FAWAIVPLFD NSVGATSGGP
310 320 330 340 350
TSPSSPLAPS VSGSSSHEGV FEPITNITLD GKLSYSSGSS VVVEISTLNK
360 370 380 390 400
VKESYTEDSL QDPKRKVHKP VKGVLRLEIE KHQTGHSDLE NLSESGSMTN
410 420 430 440 450
ESVDPGDRVN DSTFTKSPSN GSNWPQTSSS KQNIFDGRES TGNSPSAHGN
460 470 480 490 500
PELSADDFQA FDFRTTMRNE PFLQLFHWLY IYPLTVTLSR KRNLFIRVEL
510 520 530 540 550
RKDDSDVRRQ PLEAMYPREP GASLQKWAHT QVAVGARVAC YHDEIKLSLS
560 570 580 590 600
AVWTPFHHLL FTFFHVDLQT KLEAPKPVVI GYAALPLSTY DQLRSEISLP
610 620 630 640 650
IMRELVPHYL QDTGKERLDY LEDGKNIFRL RLRLCSSMYP TNERIRDFFL
660 670 680 690 700
EYDRHTLRTS PPWGSELLEA INSLKNVDST ALLQFLHPIL NMLLHLIGSG
710 720 730 740 750
GETLQVAAFR AMVNILTRVQ QESVDDAERN RFLVNYVDYA FDDFGGRQPP
760 770 780 790 800
VYPGLSTVWG SLARSKAKGY RVGPVYDDVL AMAWFFLELI VKSMALEQTR
810 820 830 840 850
LFYHSLPLGE DVPPMQLKDG VFRCIMQLYD CLLTEVHERC KKGSSLAKRL
860 870 880 890 900
NSSLAFFCYD LLSIIEPRQV FELVSLYMDK FSGVCQSVLH DCKLTFLQIV
910 920 930 940 950
CDHDLFVEMP GRDPSDRNYL SSVLIQELFI TWDHDDLSQR SKAARTLVVL
960 970 980 990 1000
LCKHEFDARY QKPEDKLYIA QLYFPLIGQI LDEMPVFYNL NAVEKREVLI
1010 1020 1030 1040 1050
VILQIVRNLD DTSLVKAWQQ SIARTRLFFK LMEECLVLFE HKKPADGMLM
1060 1070 1080 1090 1100
GSSSRSPVID APSSPKYSDR LSPAINNYLS EASRQEVRTQ GTPDNGYLWQ
1110 1120 1130 1140 1150
RVNSQLSSPS QPYSLREALA QAQSSRIGAS SQALRESLHP ILRQKLELWE
1160 1170 1180 1190 1200
ENLSAAVSLQ VLEITQKFSM MAASHSIATD YGKLDCITAI FMSFFSRNQA
1210 1220 1230 1240 1250
LAFWKALLPV FCSVFDLHGA TLMARENDRF LKQVAFHLLR LAVFRNESIR
1260 1270 1280 1290 1300
RRAVVGLKIL VRSSFYYFMQ TARLRAMLTI TLSELMSDVQ VTQMKSDGTL
1310 1320 1330 1340 1350
EESGEARRLR KSLEEMADEY KSTSLLKECG LPEDALVAIL DSSAENRWSW
1360 1370 1380 1390 1400
SDVKYLSDNL ILALDASLEH ALLASAMTID RYATAESYYK LAMAFAPVPD
1410 1420 1430 1440 1450
LHIMWLLHLC DAHQEMQSWA EAAQCAVAVA GVVMQALVAR KDGVWSKDHV
1460 1470 1480 1490 1500
TALRKICPMV SSEISSEASA AEVEGYGASK LTVDSAVKYL QLANKLFSQA
1510 1520 1530 1540 1550
ELFHFCASIL ELVIPVYKSR RAYGQLAKCH TLLTNIYESI LEQESSPIPF
1560 1570 1580 1590 1600
TDATYYRVGF YGEKFGKLDR KEYVYREPRD VRLGDIMEKL SHIYESRMDG
1610 1620 1630 1640 1650
NHTLHIIPDS RQVKADELQP GVCYLQITAV DPVMEDEDLG SRRERIFSLS
1660 1670 1680 1690 1700
TGSVRARVFD RFLFDTPFTK NGKTQGGLED QWKRRTVLQT EGSFPALVNR
1710 1720 1730 1740 1750
LLVIKSESLE FSPVENAIGM IETRTAALRN ELEEPRSSEG DQLPRLQSLQ
1760 1770 1780 1790 1800
RILQGSVAVQ VNSGVLSVCT AFLSGEPATR LRSQELQQLI AALLEFMAVC
1810 1820 1830 1840
KRAIRVHFRL IGEEDQDFHT QLVNGFQSLT AELSHYIPAI LSEL
Length:1,844
Mass (Da):208,760
Last modified:March 24, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6ED2DE11D089A154
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EQ973810 Genomic DNA Translation: EEF45723.1

NCBI Reference Sequences

More...
RefSeqi
XP_002516704.1, XM_002516658.2
XP_015573212.1, XM_015717726.1
XP_015573213.1, XM_015717727.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8261156

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rcu:8261156

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ973810 Genomic DNA Translation: EEF45723.1
RefSeqiXP_002516704.1, XM_002516658.2
XP_015573212.1, XM_015717726.1
XP_015573213.1, XM_015717727.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi3988.XP_002516704.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8261156
KEGGircu:8261156

Phylogenomic databases

InParanoidiB9RSI5
KOiK21852
OrthoDBi20156at2759

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR027007 DHR-1_domain
IPR027357 DHR-2
IPR026791 DOCK
IPR010703 DOCK_C
PANTHERiPTHR23317 PTHR23317, 1 hit
PfamiView protein in Pfam
PF06920 DHR-2, 1 hit
PF14429 DOCK-C2, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51650 DHR_1, 1 hit
PS51651 DHR_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB9RSI5_RICCO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B9RSI5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: June 5, 2019
This is version 49 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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