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Entry version 38 (05 Jun 2019)
Sequence version 1 (24 Mar 2009)
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Protein
Submitted name:

Ankyrin repeat containing protein,putative

Gene

BN1205_085300

Organism
Toxoplasma gondii (strain ATCC 50861 / VEG)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferaseImported, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ankyrin repeat containing protein,putativeImported
Submitted name:
Putative histone lysine methyltransferase, SETImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:BN1205_085300Imported, TGVEG_292170Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiToxoplasma gondii (strain ATCC 50861 / VEG)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri432359 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002226 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Partially assembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5811.TGME49_092170

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini950 – 988ANK_REP_REGIONInterPro annotationAdd BLAST39
Domaini1096 – 1224ANK_REP_REGIONInterPro annotationAdd BLAST129
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1096 – 1124ANKPROSITE-ProRule annotationAdd BLAST29
Repeati1184 – 1216ANKPROSITE-ProRule annotationAdd BLAST33

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni38 – 91DisorderedSequence analysisAdd BLAST54
Regioni668 – 687DisorderedSequence analysisAdd BLAST20
Regioni1001 – 1033DisorderedSequence analysisAdd BLAST33
Regioni1396 – 1418DisorderedSequence analysisAdd BLAST23
Regioni1435 – 1632DisorderedSequence analysisAdd BLAST198

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1486 – 1609Pro-richSequence analysisAdd BLAST124

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4177 Eukaryota
COG0666 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
B9QEJ0

Identification of Orthologs from Complete Genome Data

More...
OMAi
DHHNNTH

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit
1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011990 TPR-like_helical_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 1 hit
SSF48452 SSF48452, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 2 hits
PS50088 ANK_REPEAT, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B9QEJ0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFEKMLVGAF KASHVDDATF SLASADAATR DELLRRRRAP SHRGKQVLPG
60 70 80 90 100
GPLDGTGEER RENNTVSSDG RGGVQLDAGK GRPRSVAPGE DVAAARAADP
110 120 130 140 150
VKDLTAERRH GVLRAVGEDA PLAAGSARRR KGSALRSELV RRMEAVDESN
160 170 180 190 200
RQQDERELDL VRSTVPKLLS RQQFSDAESL LEYYLDAFPS RAELYILAAD
210 220 230 240 250
LNLEQRKFSQ AIEFYWAALF CVPENRMLIR SLRDAEERLL AEVSCIPHLY
260 270 280 290 300
KAALFDSSRF ASCHTTPRPY AEGDLYFSHP GASVWTTCES LPQLSSPQAL
310 320 330 340 350
ATEIGRRGAL QRPPFLVVKQ DKQTVCIAEV PLEPGQLIFR ELPYVCTPLT
360 370 380 390 400
LEGGQVFTTC FHCLRERPVS NRGFSCPVSP HTCPFVFCSW ECLMRNVRVH
410 420 430 440 450
SRECGLLPMI MAAAREAELS ITGVLHFCRL LLRAGLEREI VRPEKDMLYN
460 470 480 490 500
VLGELQSFEE SVEIGQPELR RKLTTLARRL EKDFPPGFYC YLQHRELIRL
510 520 530 540 550
MLLVSQYSPF VRSTSPSAAV QRRDPDASVG LVFSRRLANL PHSCVPTCTY
560 570 580 590 600
NLDEDGFVAV RALCHIPVGG RLCVSMVEDL FRPSAARKDI EAPPRVFGCG
610 620 630 640 650
CVRCSDPSEG GRMLRGIRCG VCLRGYCAPF YSPALQKRLV AYGVGGAEVA
660 670 680 690 700
RKIALLACAV EKPKAGRRRR STSPLASRFE DPRRASETAA DEAEERWQCT
710 720 730 740 750
SCGNASELLS VQCDAIEREV TQLTKKADRR FVKGKSLPAR KIYVDIIRRF
760 770 780 790 800
NSRLHPNNFL LYNAHVVAAG LLFRDPGQDV PQALLYIRRA VIAAEAVLPI
810 820 830 840 850
CHREKIHLFT QLAQISFAAS MADKLSRRGV GLPGGFVLEP MYSAYWNAAV
860 870 880 890 900
CCGPRSVLAL TTLQQLRMYA AALNVATPPA VVSYKLPTVG VIFSYFRHVL
910 920 930 940 950
GRHTESDRTL RRLVEKDPFR LATTIARLGL HCLMSLEILS AFNNVHHLGT
960 970 980 990 1000
GLSVMAIAAS QSRLTLVRKL LDAGFDFLRG NELGVTPLVA MAAMPLPQGG
1010 1020 1030 1040 1050
RSVGGGANGS VVDGRSSEQK AADRLDGAGV GLSSDAEPGE LYFRSEVADR
1060 1070 1080 1090 1100
ADRDQAEILR LFMQECSRRD ARAKEAKTKD QLMLACTHRI LGLNGPLHFA
1110 1120 1130 1140 1150
AARGKTELCR QLIRSGWNVS KSNGEGAVPL HLACASGDVQ TVMVFLVPRA
1160 1170 1180 1190 1200
MRHQDADAGD GAATPEKSES LGAFGVDINV KTERGETPLM LAAYAVQRDM
1210 1220 1230 1240 1250
VKLLLDKGAD ANVVGDREKM TVLHALAAGV CRTVEVQYEP LDPRQDLAAH
1260 1270 1280 1290 1300
VVMGLNHASL AANIYNRGPG YLYVTDTVED RIPVVSRLAP DLFIFPQEIL
1310 1320 1330 1340 1350
RRLTEANHIG ELLLRHCDHQ LFVRKTKKGY TPAELLSHLW ERFFQTRNEV
1360 1370 1380 1390 1400
VEQSELRLAA LSHQERQEIE TGWKVAGQLA YRLIELLRAG GATVEDARRP
1410 1420 1430 1440 1450
EDMTPRRTDL QERRLRQLHR DAPWLKAEEM LKGKTQGLSP ATPQSRGHEQ
1460 1470 1480 1490 1500
AAEAAKSADP RKAPLTGQTA PPAPPEAKAE PAGAQEKKAP PPPPSGEKKA
1510 1520 1530 1540 1550
PPPPPSGEKK APPPPPSGEK KGPPPPPSGE KKGPPPPPSG EKKAPPPPPS
1560 1570 1580 1590 1600
GEKKGPPPPP SGEKKAPPPP PSGEKKGPPP PPSGEKKAPP PPPSGEKKGP
1610 1620 1630
PPPPSGEKKA PPLGKKKGPP LLGKKGLPPP KK
Length:1,632
Mass (Da):178,592
Last modified:March 24, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5391B3F3B5D6C0AE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
LN714499 Genomic DNA Translation: CEL76109.1
AAYL02000084 Genomic DNA Translation: ESS33973.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
ESS33973; ESS33973; TGVEG_292170

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN714499 Genomic DNA Translation: CEL76109.1
AAYL02000084 Genomic DNA Translation: ESS33973.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi5811.TGME49_092170

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiESS33973; ESS33973; TGVEG_292170

Phylogenomic databases

eggNOGiKOG4177 Eukaryota
COG0666 LUCA
InParanoidiB9QEJ0
OMAiDHHNNTH

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.10, 1 hit
1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 5 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 2 hits
PS50088 ANK_REPEAT, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB9QEJ0_TOXGV
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B9QEJ0
Secondary accession number(s): A0A0F7V0U5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: June 5, 2019
This is version 38 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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