Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 76 (02 Jun 2021)
Sequence version 1 (24 Mar 2009)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Cation-transporting P-tyep ATPase

Gene

trd_A0479

Organism
Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocaseARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.3.24.2, the p-type atpase (p-atpase) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Cation-transporting P-tyep ATPaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:trd_A0479Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid TrosImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiThermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri309801 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaChloroflexiThermomicrobialesThermomicrobiaceaeThermomicrobium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000447 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Plasmid Tros

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei722 – 740HelicalSequence analysisAdd BLAST19
Transmembranei937 – 958HelicalSequence analysisAdd BLAST22
Transmembranei1400 – 1421HelicalSequence analysisAdd BLAST22
Transmembranei1488 – 1512HelicalSequence analysisAdd BLAST25
Transmembranei1532 – 1552HelicalSequence analysisAdd BLAST21
Transmembranei1564 – 1587HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
309801.trd_A0479

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini761 – 830Cation_ATPase_NInterPro annotationAdd BLAST70

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni75 – 101DisorderedSequence analysisAdd BLAST27

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili963 – 990Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0474, Bacteria
COG2217, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002360_0_1_0

Database of Orthologous Groups

More...
OrthoDBi
178322at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.1110.10, 1 hit
3.40.50.1000, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006068, ATPase_P-typ_cation-transptr_C
IPR004014, ATPase_P-typ_cation-transptr_N
IPR023299, ATPase_P-typ_cyto_dom_N
IPR018303, ATPase_P-typ_P_site
IPR023298, ATPase_P-typ_TM_dom_sf
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR036412, HAD-like_sf
IPR023214, HAD_sf
IPR001757, P_typ_ATPase
IPR044492, P_typ_ATPase_HD_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00689, Cation_ATPase_C, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00120, HATPASE

Structure-Function Linkage Database

More...
SFLDi
SFLDF00027, p-type_atpase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00831, Cation_ATPase_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56784, SSF56784, 1 hit
SSF81653, SSF81653, 1 hit
SSF81660, SSF81660, 1 hit
SSF81665, SSF81665, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01494, ATPase_P-type, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00154, ATPASE_E1_E2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B9L3W5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNRPRIRVLH QLPGRVRLSL DPYPPDGALA QVRRLPGILA ATGNALTGTW
60 70 80 90 100
LLRVDPALWS TEALLEELAQ RLDQSDRAAS SGEADSERPG DTASARSRRV
110 120 130 140 150
RVEHAVTRQV GTVSRRRLRL AVPGLEGNPH LAQAIEDALG RLGAAVVRAS
160 170 180 190 200
ALTGRVLVEL DESINLSEVI ASIAGLDLPE LPPSARRVIS PFDQDLLTYG
210 220 230 240 250
IVRSTGTALA LGLLVARQLL GRPAALTTSP VPSLIADALT VLRGFPTLRE
260 270 280 290 300
GMRRLLTPIG ADIATSSLGI VTQALAGQRI GLLVSFLEAL RLLTVLLPWQ
310 320 330 340 350
RAWQRYERQL AESSLPHPGA TARVSPGSRL PLPAVLEDGE LLTLSPAGTV
360 370 380 390 400
EHRTRGQTVA AGSFVLYGQA IVRYRAVEPG AAWRPRPTPL PALTQRYLDL
410 420 430 440 450
IAPLALGAAA VNGLRAGSLA AAGRALVLLN ARPALIGTEI ADLGAVARAL
460 470 480 490 500
RAGTLVTRLA PGRRLVRPSV IVLDHPLLLS DGFELDTAIS LDDALSLDEL
510 520 530 540 550
LECSARLALE QRLPFASAFP LPTNGRRNGL RDWRRFELTG ANGATHPVAQ
560 570 580 590 600
KLLERGSLPV LLCERGCGRV AGVIALRPCL SAAGRELVSR CRQQGIRVLV
610 620 630 640 650
RGAPDTRLTW LETVGVEVLA DSDPATTIAG LRRSGQRVFY VADHLGNPSA
660 670 680 690 700
FREADLGIGL QPNGVVLDYP VDVLASDLAA VMTLLDIGER RDQAVRDTTL
710 720 730 740 750
VSLASNLAAL ALGFGLPVSP TLAAILLGGS ALLAIVLSWV RLWGQPPSSV
760 770 780 790 800
APVYVDPEPE RWGDRAPDEL FREFATSPHG LSASEALRRL AIEPSDSQLS
810 820 830 840 850
PWVQAALEQL SSPLVAIMAA GAALSLAVNA PLDVLIIVGT IAVNTLLGTW
860 870 880 890 900
QDVRVARATS ELARLTETTA RVRRDGDEQL IPASELVPGD IVLLRFGDLV
910 920 930 940 950
PADARLIETN NFAVDESALT GESIPVQKDA AARDERAVVL AGSAVVSGTA
960 970 980 990 1000
VAVVVATGPR TRLGALRRSL ELSEENRDHL TERLAQYTRL SLPISFATAA
1010 1020 1030 1040 1050
AVTLSGILRG LPPAAQLGLG ASLAIAAVPE GLPLLSRVAQ AATARRLARN
1060 1070 1080 1090 1100
GIVVRRLSAA EALGRVSIVC VDKTGTLTAG KLSVTHILTS AGLESLPGQL
1110 1120 1130 1140 1150
SELARRTLTS AALASPPPSR SDAFTHGTDA AVLRAALEAG LRDRLDVPRD
1160 1170 1180 1190 1200
QELPFESTQP YHAVRIGGTA YFKGSPEVLL DRCRAWLAAD GSLQPLDDAR
1210 1220 1230 1240 1250
HAELADHLLR LAGAGLRVLL VAEADGSVRL EDPTDLRLIG FLGLSDPLRP
1260 1270 1280 1290 1300
TVPDAVARCR RAGVRVVMIT GDHPATASTI ARAAGLTEDE RVITGADLAS
1310 1320 1330 1340 1350
LSDEQLAERL EQVPVIARAT PLDKVRIVRA LQARGHVVAM TGDGVNDSAA
1360 1370 1380 1390 1400
LRLADVGMAM GWGTEVARQA ADLILIEDDF AALVQALIEG RSFWRNMRRA
1410 1420 1430 1440 1450
VALLLGGNLG ELLLMGIPSL LGAPAPLNTR QVLMVNLITD VPPALAIALQ
1460 1470 1480 1490 1500
GPRYQRLEQL AREGETALDR PLRVDVLRRA GATAVPAALA YLWAMTASPS
1510 1520 1530 1540 1550
AAPAVAFTAL VAGQLAQTLE LGLSGAGLTP SLLTGTALSG AVLAATLITP
1560 1570 1580 1590 1600
PFRALLGLPA LTPAGWLAAG LSTVAAVAAS QAIAQLVPTE AEASSPSARP

APISQPA
Length:1,607
Mass (Da):169,038
Last modified:March 24, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE9BBBEB3485B5CC1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP001276 Genomic DNA Translation: ACM07026.1

NCBI Reference Sequences

More...
RefSeqi
WP_012643013.1, NC_011961.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ACM07026; ACM07026; trd_A0479

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tro:trd_A0479

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001276 Genomic DNA Translation: ACM07026.1
RefSeqiWP_012643013.1, NC_011961.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi309801.trd_A0479

Protein family/group databases

TCDBi3.A.3.24.2, the p-type atpase (p-atpase) superfamily

Genome annotation databases

EnsemblBacteriaiACM07026; ACM07026; trd_A0479
KEGGitro:trd_A0479

Phylogenomic databases

eggNOGiCOG0474, Bacteria
COG2217, Bacteria
HOGENOMiCLU_002360_0_1_0
OrthoDBi178322at2

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR006068, ATPase_P-typ_cation-transptr_C
IPR004014, ATPase_P-typ_cation-transptr_N
IPR023299, ATPase_P-typ_cyto_dom_N
IPR018303, ATPase_P-typ_P_site
IPR023298, ATPase_P-typ_TM_dom_sf
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR036412, HAD-like_sf
IPR023214, HAD_sf
IPR001757, P_typ_ATPase
IPR044492, P_typ_ATPase_HD_dom
PfamiView protein in Pfam
PF00689, Cation_ATPase_C, 1 hit
PRINTSiPR00120, HATPASE
SFLDiSFLDF00027, p-type_atpase, 1 hit
SMARTiView protein in SMART
SM00831, Cation_ATPase_N, 1 hit
SUPFAMiSSF56784, SSF56784, 1 hit
SSF81653, SSF81653, 1 hit
SSF81660, SSF81660, 1 hit
SSF81665, SSF81665, 1 hit
TIGRFAMsiTIGR01494, ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154, ATPASE_E1_E2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB9L3W5_THERP
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B9L3W5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: June 2, 2021
This is version 76 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

PlasmidImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again