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Entry version 67 (13 Feb 2019)
Sequence version 2 (07 Sep 2016)
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Protein

Kinesin-like protein KIN-12E

Gene

KIN12E

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi145 – 152ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor protein
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Kinesin-like protein KIN-12ECurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KIN12ECurated
Ordered Locus Names:Os07g0638000Imported, LOC_Os07g44400Curated
ORF Names:OJ1340_C08.103Imported, OsJ_25289Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000059680 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Microtubule

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004371971 – 1892Kinesin-like protein KIN-12EAdd BLAST1892

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini64 – 401Kinesin motorPROSITE-ProRule annotationAdd BLAST338

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili406 – 438Sequence analysisAdd BLAST33
Coiled coili486 – 526Sequence analysisAdd BLAST41
Coiled coili1066 – 1139Sequence analysisAdd BLAST74
Coiled coili1303 – 1357Sequence analysisAdd BLAST55
Coiled coili1396 – 1528Sequence analysisAdd BLAST133
Coiled coili1780 – 1841Sequence analysisAdd BLAST62

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2 – 46Ala-richPROSITE-ProRule annotationAdd BLAST45

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.1 Publication

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JTE8 Eukaryota
ENOG410YD34 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000084308

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.850.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR24115 PTHR24115, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00225 Kinesin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00380 KINESINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00129 KISc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B9FUF9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGHGAGGRR ASTSRAAARR VEAETNENDD LAAAAARDLA AAEVPAEVPH
60 70 80 90 100
FELDEDPAFW KDRNVQVLIR IRPINAAEST ANGQRRCLVQ DSSKTLSWTG
110 120 130 140 150
HPDTMFTFDH VACETISQEK LFGVVGLPMV ENCMSGYNGC LFAYGQTGSG
160 170 180 190 200
KTYTMMGELS KLDNELSKDS GLTPRIFEYL FARIKEEEER RREDKLKYIC
210 220 230 240 250
KCSFLEIYNE QITDLLEPSS TNLQIREDIK KGVYVENLME CYVSSVKDVM
260 270 280 290 300
MLLLQGVANR KMAATNMNSE SSRSHSVFTC VIESRWERDS MTHLRFGRLN
310 320 330 340 350
LVDLAGSERQ KSSGAEGERL KEAANINRSL STLGLVIMTL VDVANGKNRH
360 370 380 390 400
VPYRDSRLTF LLQDSLGGNS KTTIVANVSP SICSSSETLS TLKFAQRAKL
410 420 430 440 450
IQNNAKVNED ASGDVMSLQR QIEDLKDQLT CLKKQQNMPG SPSFKLLKSG
460 470 480 490 500
YGNEFNSLHG VDDQSACDLE LLKQKVIHLE DVLVGSLRRE KSAETEIRKL
510 520 530 540 550
ECEIKSLNRL VNLMESDTRH LRTTVKLRDE KIRRLELLAD NQISSDGYLM
560 570 580 590 600
DENAAMFQEI QLLQEQINDN SQLTQFALEN KRLIEQVRML EKFSKQGERE
610 620 630 640 650
MLLTEISLLR NHFLHILEQK YARPPKNMEA QGDVTIKELE TCRKELDACL
660 670 680 690 700
ENNVLLAREV NKLRCELKQY QKCGTGQVAP EVVESSVIPG INQKQHDQAG
710 720 730 740 750
WCGSYLASID VERQFVDVGI TTDITESLEL TPPSEIYSEN QDSPSRLHFS
760 770 780 790 800
DPEICDLKNS TKVLEYNSSR NLLDKGIILS GQLENECGLN SVQNDEISLV
810 820 830 840 850
KENAEKMYGH DEISVYRQNE ILHSSEQLLQ DELTHIKSLN EGLKEKLIIM
860 870 880 890 900
AEESTKLSEI IVAKDVEIAT LSEEWESAIV DLTSFLTDGC SSLDDAYQNI
910 920 930 940 950
DNMISSFPYN NHSVSEHVEK AMKVSIEKEK IISRLQIELQ AAQRMGREVK
960 970 980 990 1000
EKLHILRGAT LAITEAQLLD NDESQEALKL LDLMRQKDCT VQELNDNVKQ
1010 1020 1030 1040 1050
KSCLFAEATE GYSRHECHLP DNVGTVAEIS HNRDGSEVNQ ANTHYQAKLE
1060 1070 1080 1090 1100
DVLHLVEDKS NKVLALFSNF EEAQETMEEA ETMLSSLLKA NEELKLEKDS
1110 1120 1130 1140 1150
CRQAVELLFA ERTSLINDLQ ELEASNSFTA QRYDKLHEQV NGCVAEMTNL
1160 1170 1180 1190 1200
ATIIKESFHQ VQRVTTVELF AFCSEVISFG QDLRKWIYES RSYLVNMGAL
1210 1220 1230 1240 1250
LEEQGNSYAE QNRRTNSSTY AGVSQQVESC SRQLGGMNGD IFPGTYMVVD
1260 1270 1280 1290 1300
GKEKASVHVV PFGSNAELED TNVERTFDMD YASLRREFDR KSDVAEGLSF
1310 1320 1330 1340 1350
DLKLLQESTS QAKDMKDKAD EISDALVSVQ RELEKKTSAM ESILKQQKVL
1360 1370 1380 1390 1400
EEELAENGAA LLILRSELEH SESLSSELFK ENNNLKVMLE EEAMMISETK
1410 1420 1430 1440 1450
AMLEDKSKVI EGLEHEILLL NSSEEGRLMS QIKELNDNLK IISIDKGNLE
1460 1470 1480 1490 1500
EEILKLTDKL EMAVALAEEN EAASIEARQA AEISKVYAEE KEEEVRILER
1510 1520 1530 1540 1550
SVEELESTIT VLEEEVCNLK EEVRSYQIYK KSEAEQAQEM FIVDSTSKCD
1560 1570 1580 1590 1600
ATEQLCPGRC QLEKRLKAEI IAHQDARRKI ECLTMEASCK DEEVRQYKEH
1610 1620 1630 1640 1650
IAELVLHSEA QSLLFQEKYQ EMEHMISKQK FGLHESNSDT GHTKFEKPSG
1660 1670 1680 1690 1700
RTRGSGSPFR CISSIVQQMN SEKDQEISVA RQRIEELEGL VCNKQKEICM
1710 1720 1730 1740 1750
LTSRLAAVDS MTHDIIRELL GVKLDMTNYA NMLDQEELQK LLMASQQQIE
1760 1770 1780 1790 1800
QSKAKDVELD MLKEQFDHLI QERDSLFDDM DQRKADLLES QLLIEQLEQR
1810 1820 1830 1840 1850
EQMLEAQNGI LQMEKDNLQQ RIMEMDEEIQ LLVGSNQAIA ETTFQMGSNH
1860 1870 1880 1890
RSANSEFSRR LAQSDMLLSH ARHEHSRLQA AKSSRTRRGS HQ
Length:1,892
Mass (Da):214,446
Last modified:September 7, 2016 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i33062625AD6323A3
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD31261 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAF22319 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAG87394 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAT02836 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence EEE67666 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AP005292 Genomic DNA Translation: BAD31261.1 Sequence problems.
AP008213 Genomic DNA Translation: BAF22319.2 Sequence problems.
AP014963 Genomic DNA Translation: BAT02836.1 Sequence problems.
CM000144 Genomic DNA Translation: EEE67666.1 Sequence problems.
AK060298 mRNA Translation: BAG87394.1 Different initiation.

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Os.5059

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005292 Genomic DNA Translation: BAD31261.1 Sequence problems.
AP008213 Genomic DNA Translation: BAF22319.2 Sequence problems.
AP014963 Genomic DNA Translation: BAT02836.1 Sequence problems.
CM000144 Genomic DNA Translation: EEE67666.1 Sequence problems.
AK060298 mRNA Translation: BAG87394.1 Different initiation.
UniGeneiOs.5059

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410JTE8 Eukaryota
ENOG410YD34 LUCA
HOGENOMiHOG000084308

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 2 hits
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKN12E_ORYSJ
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B9FUF9
Secondary accession number(s): A0A0P0X9F0, Q0D4A4, Q69R12
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 7, 2016
Last sequence update: September 7, 2016
Last modified: February 13, 2019
This is version 67 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
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