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Entry version 81 (11 Dec 2019)
Sequence version 1 (24 Mar 2009)
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Protein
Submitted name:

Zinc finger protein 608

Gene

Zfp608

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Zinc finger protein 608Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zfp608Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2442338 Zfp608

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000052713 Expressed in 232 organ(s), highest expression level in rostral migratory stream

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini554 – 577C2H2-typeInterPro annotationAdd BLAST24

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 20DisorderedSequence analysisAdd BLAST20
Regioni49 – 72DisorderedSequence analysisAdd BLAST24
Regioni85 – 239DisorderedSequence analysisAdd BLAST155
Regioni256 – 293DisorderedSequence analysisAdd BLAST38
Regioni416 – 542DisorderedSequence analysisAdd BLAST127
Regioni611 – 665DisorderedSequence analysisAdd BLAST55
Regioni776 – 836DisorderedSequence analysisAdd BLAST61
Regioni925 – 994DisorderedSequence analysisAdd BLAST70
Regioni1013 – 1065DisorderedSequence analysisAdd BLAST53
Regioni1116 – 1195DisorderedSequence analysisAdd BLAST80
Regioni1219 – 1334DisorderedSequence analysisAdd BLAST116
Regioni1422 – 1468DisorderedSequence analysisAdd BLAST47

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi50 – 72PolarSequence analysisAdd BLAST23
Compositional biasi148 – 180PolarSequence analysisAdd BLAST33
Compositional biasi186 – 218PolyampholyteSequence analysisAdd BLAST33
Compositional biasi489 – 512PolarSequence analysisAdd BLAST24
Compositional biasi523 – 542PolarSequence analysisAdd BLAST20
Compositional biasi816 – 836PolyampholyteSequence analysisAdd BLAST21
Compositional biasi926 – 940PolarSequence analysisAdd BLAST15
Compositional biasi955 – 991PolarSequence analysisAdd BLAST37
Compositional biasi1028 – 1051PolyampholyteSequence analysisAdd BLAST24
Compositional biasi1121 – 1143PolyampholyteSequence analysisAdd BLAST23
Compositional biasi1144 – 1195PolarSequence analysisAdd BLAST52
Compositional biasi1253 – 1274PolyampholyteSequence analysisAdd BLAST22
Compositional biasi1291 – 1322PolyampholyteSequence analysisAdd BLAST32
Compositional biasi1433 – 1454PolyampholyteSequence analysisAdd BLAST22

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIE1 Eukaryota
ENOG410Z79M LUCA

Identification of Orthologs from Complete Genome Data

More...
OMAi
DRHSPFS

Database of Orthologous Groups

More...
OrthoDBi
60503at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040010 ZN608/ZN609
IPR013087 Znf_C2H2_type

The PANTHER Classification System

More...
PANTHERi
PTHR21564 PTHR21564, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B9EKR3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVNVSTAGK GVDPNTVDTY DSGDDWEIGV GNLIIDLDAD LEKDRQKFEM
60 70 80 90 100
NNSTNTTTNT TKDCGGPASN GTCSTSALAD GLKFASVQPS APQGNSHKET
110 120 130 140 150
SKSKVKRAKT SKDANKSLPS AALYGIPEIS STGKRQEVQG RPGEATGMNS
160 170 180 190 200
ALGQSVSGGG SSNPNSNGTS TGTSAATAGA GSCGKSKEEK PGKSHSSRGA
210 220 230 240 250
KRDKDAARSR KEKHDLLQGH QNGGGGQAPS GGHLYGFGTK SNGSGASPFH
260 270 280 290 300
CGGAGSGSVG AAGEVSKTAP DSTLMGNSML VKKEEEEEES HRRIKKLKTE
310 320 330 340 350
KVDPLFTVPA PPPPIASSLA PQIPPSYFPP SSSNIAAPVE QLLVRTRSVG
360 370 380 390 400
VNTCEVGVVT EPECLGPCEP GTSVNLEGIV WHETEEGVLV VNVTWRNKTY
410 420 430 440 450
VGTLLDCTKH DWAPPRFCES PTSDLEMRGG RGRGKRARSA AAAPGSEVSF
460 470 480 490 500
TESRGLQSKN RGGANGKGRR GSLNASGRRT PPNCAAEDIK ASPSSTNKRK
510 520 530 540 550
NKPPMELDLN SSSEDSKPGK RVRTNSRSTP TTPQGKPETT FLDQGCSSPV
560 570 580 590 600
LIDCPHPNCN KKYKHINGLR YHQAHAHLDP ENKLEFEPDS EDKISDCEEA
610 620 630 640 650
LSNVALECNE SSTSVSSYDQ TKAPGSPGAG NPPGTPKGKR EHVSNGPGPI
660 670 680 690 700
IGSKTGKNSG KKRGLNNELN NLPVISNMTA ALDICSATDS NLTAEMPKLE
710 720 730 740 750
AEGLIDKKSL GDKEKGKKAN NCKMDKNLSK LKSARPIAPA PAPTPPQLIA
760 770 780 790 800
IPTAAFTSTT TGTIPGLPSL TTTVVQATPK SPPLKPIQPK PTIMGEPITV
810 820 830 840 850
NPALVSLKDR KKKEKRKLKD KEGKETGGPK MDAKLGKLEE AKAASKDLSG
860 870 880 890 900
HFLKDHLGKS EGLANGLSES QESRMASIKA EADKVYTFTD NAPSPSIGSA
910 920 930 940 950
SRMECSTLVN GQAPMAPLHV LTQNGAESAA AKTSSPAYSD ISDAADDGGS
960 970 980 990 1000
DSRSEGMRSK ASSPSDTFSN KDGVVKGHPS TSAQPSQLKE SHSPYYHGYE
1010 1020 1030 1040 1050
PYYSPSYMHP GQVGAPAAGN GGSTQGMKIK KESEEDAEKK DKAEQLESKK
1060 1070 1080 1090 1100
VDHTSAPLQP QHQSVITQRH PALAQSLYYG QYAYGLYMDQ KSLMATSPAY
1110 1120 1130 1140 1150
RQQYEKYYED QRLAEQKMAQ SGRGDCERKA ELPLKELGKE DNKQKNMPSA
1160 1170 1180 1190 1200
TISKAPSTPE PNKNHSKLGP SVPNKTEETG KSQLLSSHQQ QLQADSFKAK
1210 1220 1230 1240 1250
QMENHQLIKE AVEMKSVMDS MKQTGVDPTS RFKQDPESRT WHHYVYQPKY
1260 1270 1280 1290 1300
LDQQKPEELD REKKLKEDSP RKTPNKESGV SSLPVSLTNI KEEPKEGKRP
1310 1320 1330 1340 1350
DSQSVEENKL KNDDRKTPVN WKDSRGTRVA VSSPMSQHQS YIQYLHAYPY
1360 1370 1380 1390 1400
PQMYDPSHPA YRAVSPVLMH SYPGAYLSPG FHYPVYGKMS GREEAEKVNT
1410 1420 1430 1440 1450
SPSINTKTAS EAKALDLLQH HANQYRSKSP APVEKASTER EREAERERDR
1460 1470 1480 1490 1500
HSPFSQRHLH THHHTHVGMG YPLIPGQYDP FQGLTSAALV ASQQVAAQAS
1510
ASGMFPAQRR E
Length:1,511
Mass (Da):162,345
Last modified:March 24, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4331F1298053D5AC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC151073 mRNA Translation: AAI51074.1
BC151075 mRNA Translation: AAI51076.1

NCBI Reference Sequences

More...
RefSeqi
NP_786927.2, NM_175751.4
XP_006526020.1, XM_006525957.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
269023

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:269023

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC151073 mRNA Translation: AAI51074.1
BC151075 mRNA Translation: AAI51076.1
RefSeqiNP_786927.2, NM_175751.4
XP_006526020.1, XM_006525957.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi269023
KEGGimmu:269023

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
269023
MGIiMGI:2442338 Zfp608

Phylogenomic databases

eggNOGiENOG410IIE1 Eukaryota
ENOG410Z79M LUCA
OMAiDRHSPFS
OrthoDBi60503at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Zfp608 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000052713 Expressed in 232 organ(s), highest expression level in rostral migratory stream

Family and domain databases

InterProiView protein in InterPro
IPR040010 ZN608/ZN609
IPR013087 Znf_C2H2_type
PANTHERiPTHR21564 PTHR21564, 1 hit
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB9EKR3_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B9EKR3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 11, 2019
This is version 81 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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