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Protein
Submitted name:

TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor

Gene

Taf2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-674695 RNA Polymerase II Pre-transcription Events
R-MMU-6804756 Regulation of TP53 Activity through Phosphorylation
R-MMU-73776 RNA Polymerase II Promoter Escape
R-MMU-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-MMU-75953 RNA Polymerase II Transcription Initiation
R-MMU-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance

Names & Taxonomyi

Protein namesi
Submitted name:
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factorImported
Submitted name:
Transcription initiation factor TFIID subunit 2Imported
Gene namesi
Name:Taf2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:2443028 Taf2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000037343 Expressed in 241 organ(s), highest expression level in pes

Interactioni

GO - Molecular functioni

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1932 Eukaryota
ENOG410XS52 LUCA
GeneTreeiENSGT00390000000420
HOGENOMiHOG000046103
HOVERGENiHBG094022
KOiK03128
OMAiSHGICPP
OrthoDBiEOG091G00Z3
TreeFamiTF315208

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR037813 TAF2
PANTHERiPTHR15137 PTHR15137, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

B9EJX5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPPTGLESSR MNRKKGDKGF ESPRPYKLTH QVVCINNINF QRKSVVGFVE
60 70 80 90 100
LTIFPTVANL NRIKLNSKQC RIYRVRINDL EAAFIYNDPT LEVCHSESKQ
110 120 130 140 150
RNLNYFSNAY AAAVSAVDPD AGNGELCIKV PSELWKHVDE LKVLKIHINF
160 170 180 190 200
SLDQPKGGLH FVVPSVEGSM AERGAHVFSC GYQNSTRFWF PCVDSYSELC
210 220 230 240 250
TWKLEFTVDA AMVAVSNGDL VETVYTHDMR KKTFHYMLTI PTAASNISLA
260 270 280 290 300
IGPFEILVDP YMHEVTHFCL PQLLPLLKHT TSYIHEVFEF YEEILTCRYP
310 320 330 340 350
YSCFKTVFID EAYVEVAAYA SMSIFSTNLL HSAMIIDETP LTRRCLAQAL
360 370 380 390 400
AQQFFGCFIS RMSWSDEWVL KGISGYIYGL WMKKTFGVNE YHHWIKEELD
410 420 430 440 450
KIVAYELKTG GVLLHPIFGG GKEKDNPASH LHFSIKHPHT LSWEYYTMFQ
460 470 480 490 500
CKAHLVMRLI ENRISMEFML QVFNKLLSLA STASSQKFQS HMWSQMLVST
510 520 530 540 550
YGFLKSISNV SGKDIQPLIK QWVDQSGVVK FYGSFAFNRK RNVLELEIKQ
560 570 580 590 600
DYTSPGTQKY VGPLKVTVQE LDGSFNHTLQ IEENSLKHDI PCHSKSRRNK
610 620 630 640 650
KKKIPLMNGE EVDMDLSAMD ADSPLLWIRI DPDMSVLRKV EFEQADFMWQ
660 670 680 690 700
YELRYERDVV AQQESILALE KFPTPASRLA LTDILEQEQC FYRVRMSACF
710 720 730 740 750
CLAKIANSMV STWTGPPAMK SLFTRMFCCK TCPNIVKTNN FMSFQSYFLQ
760 770 780 790 800
KTMPVAMALL RDVHNLCPKE VLTFILDLIK YNDNRKNKFS DNYYRAEMID
810 820 830 840 850
ALANSVTPAV SVNNEVRTLD NLNPDVRLIL EEITRFLNME KLLPSYRHTI
860 870 880 890 900
TVSCLRAIRV LQKNGHVPSD ASLFKSYAEY GHFVDIRIAA LEAVVDYTKV
910 920 930 940 950
DRSYEELQWL LNMIQTDPVP YVRHKILNML TKNPPFTKNM ESPLCNEALV
960 970 980 990 1000
DQLWKLMNSG TAHDWRLRCG AVDLYFTLFG LSRPSCLPLP ELGLVLNLKE
1010 1020 1030 1040 1050
KKAVLNPTII PEAGVGNQES ASNPGCHAQL AGFQNPFSSS QDEEEVDMDT
1060 1070 1080 1090 1100
VHDSQAFISH HLNMLERPST PGLSKYRPSG SRSSLMPQHS LGCDITPPTK
1110 1120 1130 1140 1150
PQWSMELSRK GAGKEQPLEM GVHSMVAAPL SMFAKEALSS RHSEHHHHHH
1160 1170 1180 1190
HEHKKKKKKH KHKHKHKHKH DSKDKDREPF AFSSPASGRS VRSPSLSD
Length:1,198
Mass (Da):136,926
Last modified:March 24, 2009 - v1
Checksum:i9FA604069E20829C
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8C176TAF2_MOUSE
Transcription initiation factor TFI...
Taf2
1,104Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC137950 Genomic DNA No translation available.
BC147638 mRNA Translation: AAI47639.1
BC151079 mRNA Translation: AAI51080.1
RefSeqiNP_001074757.1, NM_001081288.1
UniGeneiMm.380957

Genome annotation databases

EnsembliENSMUST00000041733; ENSMUSP00000043733; ENSMUSG00000037343
GeneIDi319944
KEGGimmu:319944
UCSCiuc007vrt.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC137950 Genomic DNA No translation available.
BC147638 mRNA Translation: AAI47639.1
BC151079 mRNA Translation: AAI51080.1
RefSeqiNP_001074757.1, NM_001081288.1
UniGeneiMm.380957

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000041733; ENSMUSP00000043733; ENSMUSG00000037343
GeneIDi319944
KEGGimmu:319944
UCSCiuc007vrt.1 mouse

Organism-specific databases

CTDi6873
MGIiMGI:2443028 Taf2

Phylogenomic databases

eggNOGiKOG1932 Eukaryota
ENOG410XS52 LUCA
GeneTreeiENSGT00390000000420
HOGENOMiHOG000046103
HOVERGENiHBG094022
KOiK03128
OMAiSHGICPP
OrthoDBiEOG091G00Z3
TreeFamiTF315208

Enzyme and pathway databases

ReactomeiR-MMU-674695 RNA Polymerase II Pre-transcription Events
R-MMU-6804756 Regulation of TP53 Activity through Phosphorylation
R-MMU-73776 RNA Polymerase II Promoter Escape
R-MMU-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-MMU-75953 RNA Polymerase II Transcription Initiation
R-MMU-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance

Miscellaneous databases

ChiTaRSiTaf2 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000037343 Expressed in 241 organ(s), highest expression level in pes

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR037813 TAF2
PANTHERiPTHR15137 PTHR15137, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB9EJX5_MOUSE
AccessioniPrimary (citable) accession number: B9EJX5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: November 7, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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