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Protein

Beta-lactamase

Gene

penB1

Organism
Burkholderia cenocepacia
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

A beta-lactam + H2O = a substituted beta-amino acid.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processAntibiotic resistanceUniRule annotationSAAS annotation

Enzyme and pathway databases

BRENDAi3.5.2.6 8982

Protein family/group databases

MEROPSiS11.A01

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-lactamaseUniRule annotationSAAS annotation (EC:3.5.2.6UniRule annotationSAAS annotation)
Gene namesi
Name:penB1Imported
OrganismiBurkholderia cenocepaciaImported
Taxonomic identifieri95486 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL1641339

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500287815528 – 312Beta-lactamaseSequence analysisAdd BLAST285

Structurei

3D structure databases

ProteinModelPortaliB8R6A5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-A beta-lactamase family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4108J4B Bacteria
COG2367 LUCA

Family and domain databases

InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR000871 Beta-lactam_class-A
IPR023650 Beta-lactam_class-A_AS
IPR006311 TAT_signal
PRINTSiPR00118 BLACTAMASEA
SUPFAMiSSF56601 SSF56601, 1 hit
PROSITEiView protein in PROSITE
PS00146 BETA_LACTAMASE_A, 1 hit
PS51318 TAT, 1 hit

Sequencei

Sequence statusi: Complete.

B8R6A5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTYSSKRRTL LLAAATAPLV LTATACASRQ AAAPDPATAA AAAAADAMAP
60 70 80 90 100
AAAAATLADL ERDAGGRLGV CAIDTASGRV IEHRAGERFP FCSTFKAMLS
110 120 130 140 150
AAVLAQSVER PGLLQQRVKY TKADLVNYSP VSEKHVGAGM TVAALCEATI
160 170 180 190 200
QYSDNSAANL LMKLIGGPSA VTAYARSIGD DAFRLDRWET ELNTALPGDP
210 220 230 240 250
RDTTTPAAMA ASIRVLTLGD ALPAAQRAQL VAWLRGNKVG DKRIRAGVPA
260 270 280 290 300
GWTVGDKTGT GDYGTTNDAG VIWPTSRAPI VLAVYYTQTR ADARAKDDVI
310
ASVARIVAQT FG
Length:312
Mass (Da):32,377
Last modified:March 3, 2009 - v1
Checksum:i33B9E4023E08CF87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU872211 Genomic DNA Translation: ACJ63454.1

Similar proteinsi

Entry informationi

Entry nameiB8R6A5_9BURK
AccessioniPrimary (citable) accession number: B8R6A5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 5, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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