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Protein
Submitted name:

Liprin-alpha 4

Gene

Ppfia4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-181429 Serotonin Neurotransmitter Release Cycle
R-MMU-181430 Norepinephrine Neurotransmitter Release Cycle
R-MMU-210500 Glutamate Neurotransmitter Release Cycle
R-MMU-212676 Dopamine Neurotransmitter Release Cycle
R-MMU-264642 Acetylcholine Neurotransmitter Release Cycle
R-MMU-388844 Receptor-type tyrosine-protein phosphatases

Names & Taxonomyi

Protein namesi
Submitted name:
Liprin-alpha 4Imported
Submitted name:
Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF),-interacting protein (liprin), alpha 4Imported
Gene namesi
Name:Ppfia4Imported
Synonyms:ppfia4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1915757 Ppfia4

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSMUSG00000026458 Expressed in 248 organ(s), highest expression level in pineal body

Interactioni

Protein-protein interaction databases

IntActiB8QI36, 1 interactor
B8QI36, 1 interactor
STRINGi10090.ENSMUSP00000128314

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini829 – 895SAMInterPro annotationAdd BLAST67
Domaini951 – 1008SAMInterPro annotationAdd BLAST58
Domaini1032 – 1101SAMInterPro annotationAdd BLAST70

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili30 – 71Sequence analysisAdd BLAST42
Coiled coili87 – 121Sequence analysisAdd BLAST35
Coiled coili165 – 192Sequence analysisAdd BLAST28
Coiled coili228 – 311Sequence analysisAdd BLAST84
Coiled coili315 – 360Sequence analysisAdd BLAST46
Coiled coili378 – 412Sequence analysisAdd BLAST35
Coiled coili445 – 472Sequence analysisAdd BLAST28
Coiled coili567 – 608Sequence analysisAdd BLAST42
Coiled coili1005 – 1025Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0249 Eukaryota
ENOG410XP8Z LUCA
GeneTreeiENSGT00760000119138
HOGENOMiHOG000017513
HOVERGENiHBG052330
OrthoDBiEOG091G14UK
TreeFamiTF314207

Family and domain databases

CDDicd09562 SAM_liprin-alpha1_2_3_4_repeat, 1 hit
cd09565 SAM_liprin-alpha1_2_3_4_repeat, 1 hit
cd09568 SAM_liprin-alpha1_2_3_4_repeat, 1 hit
InterProiView protein in InterPro
IPR029515 Liprin
IPR037620 Liprin-alpha_SAM_rpt_1
IPR037621 Liprin-alpha_SAM_rpt_2
IPR037622 Liprin-alpha_SAM_rpt_3
IPR030439 PPFIA4
IPR001660 SAM
IPR013761 SAM/pointed_sf
PANTHERiPTHR12587 PTHR12587, 1 hit
PTHR12587:SF5 PTHR12587:SF5, 1 hit
PfamiView protein in Pfam
PF00536 SAM_1, 2 hits
PF07647 SAM_2, 1 hit
SMARTiView protein in SMART
SM00454 SAM, 3 hits
SUPFAMiSSF47769 SSF47769, 3 hits
PROSITEiView protein in PROSITE
PS50105 SAM_DOMAIN, 3 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

B8QI36-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MCEVMPTINE GDPLGPPHGA DAEANFEQLM VNMLDEREKL LESLRESQET
60 70 80 90 100
LVATQSRLQD ALHERDQLQR HLNSALPQEF ATLTRELSMC REQLLEREEE
110 120 130 140 150
ISELKAERNN TRLLLEHLEC LVSRHERSLR MTVVKRQAQS PSGVSSEVEV
160 170 180 190 200
LKALKSLFEH HKALDEKVRE RLRAALERVT TLEEQLAGAH QQVSALQQGA
210 220 230 240 250
GIRDGVAEEE GTVDLGPKRL WKDDTGRVEE LQGLLEKQNY ELSQARERLV
260 270 280 290 300
TLSATVTELE EDLGTARRDL IKSEELSSKH QRDLREALAQ KEDMEERITT
310 320 330 340 350
LEKRYLAAQR EATSIHDLND KLENELANKE SLHRQCEEKA RHLQELLEVA
360 370 380 390 400
EQKLQQTMRK AETLPEVEAE LSQRIAALTK AEERHGNIEE HLRQLEGQLE
410 420 430 440 450
EKNQELARVR QREKMNEDHN KRLSDTVDRL LSESNERLQL HLKERMAALE
460 470 480 490 500
EKGRLSEEIE KLRQEVDQLK GRGGPFVDGI HSRSHVGSAA DVRFSLSTAT
510 520 530 540 550
HAPPGLHRRY SALRDESAKD WKPSPLPGVL GATTPAFDSD PEISDVDEDE
560 570 580 590 600
PGGLVGTQVD VISPGGHSDA QTLAMMLQEQ LDAINQEIRM IQEEKESTEL
610 620 630 640 650
RAEEIETRVT SGSMEALNLT QLRKRGSIPT SLTALSLASA SPPLSGRSTP
660 670 680 690 700
KLTSRSAAQD LDRMGVMTLP SDLRKHRRKL LSPVSREENR EDKATIKCET
710 720 730 740 750
SPPSSPRTLR LEKLGHPGLS QEEGKSALEG QDSNPSSSNS SQDSLHKGAK
760 770 780 790 800
RKGIKSSIGR LFGKKEKGRL IQLSRDATGH VLLTDSELSL QEPMVPAKLG
810 820 830 840 850
TQAEKDRRLK KKHQLLEDAR RKGMPFAQWD GPTVVSWLEL WVGMPAWYVA
860 870 880 890 900
ACRANVKSGA IMSALSDTEI QREIGISNAL HRLKLRLAIQ EMVSLTSPSA
910 920 930 940 950
PPTSRTSSGN VWVTHEEMET LATSTKTDSE EGSWAQTLAY GDMNHEWIGN
960 970 980 990 1000
EWLPSLGLPQ YRSYFMECLV DARMLDHLTK KDLRVHLKMV DSFHRTSLQY
1010 1020 1030 1040 1050
GIMCLKRLNY DRKELEKRRE ESQHEIKDVL VWTNDQVVHW VQSIGLRDYA
1060 1070 1080 1090 1100
GNLHESGVHG ALLALDENFD HNTLALVLQI PTQSTQARQV MEREFNNLLA
1110 1120 1130 1140 1150
LGTDRKLDDG EEKVFRRAPS WRKRFRPRDH HSGGMLGTSA ETLPAGFRVS
1160 1170 1180
TLGPLQPPPA PPKKIMPEAG TAGAQRLEPS TVRTYSC
Length:1,187
Mass (Da):133,713
Last modified:March 3, 2009 - v1
Checksum:i44C94BE3611D62BC
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WPM2A0A087WPM2_MOUSE
MCG5343
Ppfia4 mCG_5343
1,184Annotation score:
A0A087WPJ3A0A087WPJ3_MOUSE
Protein tyrosine phosphatase, recep...
Ppfia4
892Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124110 Genomic DNA No translation available.
EU568872 mRNA Translation: ACE63190.1
RefSeqiNP_001138327.1, NM_001144855.1
UniGeneiMm.295105

Genome annotation databases

EnsembliENSMUST00000168515; ENSMUSP00000128314; ENSMUSG00000026458
GeneIDi68507
KEGGimmu:68507
UCSCiuc011wse.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124110 Genomic DNA No translation available.
EU568872 mRNA Translation: ACE63190.1
RefSeqiNP_001138327.1, NM_001144855.1
UniGeneiMm.295105

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB8QI36, 1 interactor
B8QI36, 1 interactor
STRINGi10090.ENSMUSP00000128314

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000168515; ENSMUSP00000128314; ENSMUSG00000026458
GeneIDi68507
KEGGimmu:68507
UCSCiuc011wse.1 mouse

Organism-specific databases

CTDi8497
MGIiMGI:1915757 Ppfia4

Phylogenomic databases

eggNOGiKOG0249 Eukaryota
ENOG410XP8Z LUCA
GeneTreeiENSGT00760000119138
HOGENOMiHOG000017513
HOVERGENiHBG052330
OrthoDBiEOG091G14UK
TreeFamiTF314207

Enzyme and pathway databases

ReactomeiR-MMU-181429 Serotonin Neurotransmitter Release Cycle
R-MMU-181430 Norepinephrine Neurotransmitter Release Cycle
R-MMU-210500 Glutamate Neurotransmitter Release Cycle
R-MMU-212676 Dopamine Neurotransmitter Release Cycle
R-MMU-264642 Acetylcholine Neurotransmitter Release Cycle
R-MMU-388844 Receptor-type tyrosine-protein phosphatases

Miscellaneous databases

PROiPR:B8QI36
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000026458 Expressed in 248 organ(s), highest expression level in pineal body

Family and domain databases

CDDicd09562 SAM_liprin-alpha1_2_3_4_repeat, 1 hit
cd09565 SAM_liprin-alpha1_2_3_4_repeat, 1 hit
cd09568 SAM_liprin-alpha1_2_3_4_repeat, 1 hit
InterProiView protein in InterPro
IPR029515 Liprin
IPR037620 Liprin-alpha_SAM_rpt_1
IPR037621 Liprin-alpha_SAM_rpt_2
IPR037622 Liprin-alpha_SAM_rpt_3
IPR030439 PPFIA4
IPR001660 SAM
IPR013761 SAM/pointed_sf
PANTHERiPTHR12587 PTHR12587, 1 hit
PTHR12587:SF5 PTHR12587:SF5, 1 hit
PfamiView protein in Pfam
PF00536 SAM_1, 2 hits
PF07647 SAM_2, 1 hit
SMARTiView protein in SMART
SM00454 SAM, 3 hits
SUPFAMiSSF47769 SSF47769, 3 hits
PROSITEiView protein in PROSITE
PS50105 SAM_DOMAIN, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiB8QI36_MOUSE
AccessioniPrimary (citable) accession number: B8QI36
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 7, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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