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Entry version 56 (02 Jun 2021)
Sequence version 1 (03 Mar 2009)
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Protein
Submitted name:

Predicted protein

Gene

POSPLDRAFT_19047

Organism
Postia placenta (strain ATCC 44394 / Madison 698-R) (Brown rot fungus) (Poria monticola)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Predicted proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:POSPLDRAFT_19047Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPostia placenta (strain ATCC 44394 / Madison 698-R) (Brown rot fungus) (Poria monticola)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri561896 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesPolyporalesDacryobolaceaePostia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001743 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 67LIM zinc-bindingInterPro annotationAdd BLAST60
Domaini68 – 127LIM zinc-bindingInterPro annotationAdd BLAST60
Domaini990 – 1037Phorbol-ester/DAG-typeInterPro annotationAdd BLAST48
Domaini1062 – 1257Rho-GAPInterPro annotationAdd BLAST196

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni128 – 330DisorderedSequence analysisAdd BLAST203
Regioni343 – 525DisorderedSequence analysisAdd BLAST183
Regioni586 – 648DisorderedSequence analysisAdd BLAST63
Regioni947 – 967DisorderedSequence analysisAdd BLAST21
Regioni1039 – 1060DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili683 – 710Sequence analysisAdd BLAST28
Coiled coili845 – 865Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi132 – 149Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi157 – 190Polar residuesSequence analysisAdd BLAST34
Compositional biasi200 – 222Polar residuesSequence analysisAdd BLAST23
Compositional biasi258 – 280Polar residuesSequence analysisAdd BLAST23
Compositional biasi295 – 326Polar residuesSequence analysisAdd BLAST32
Compositional biasi343 – 375Polar residuesSequence analysisAdd BLAST33
Compositional biasi387 – 401Polar residuesSequence analysisAdd BLAST15
Compositional biasi420 – 434Polar residuesSequence analysisAdd BLAST15
Compositional biasi442 – 463Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi492 – 517Basic and acidic residuesSequence analysisAdd BLAST26
Compositional biasi586 – 614Polar residuesSequence analysisAdd BLAST29

Keywords - Domaini

Coiled coilSequence analysis, LIM domainPROSITE-ProRule annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003874_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
B8PK46

Identification of Orthologs from Complete Genome Data

More...
OMAi
LICNNCT

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00029, C1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.555.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002219, PE/DAG-bd
IPR008936, Rho_GTPase_activation_prot
IPR000198, RhoGAP_dom
IPR001781, Znf_LIM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00412, LIM, 2 hits
PF00620, RhoGAP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00109, C1, 1 hit
SM00132, LIM, 2 hits
SM00324, RhoGAP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48350, SSF48350, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00478, LIM_DOMAIN_1, 2 hits
PS50023, LIM_DOMAIN_2, 2 hits
PS50238, RHOGAP, 1 hit
PS00479, ZF_DAG_PE_1, 1 hit
PS50081, ZF_DAG_PE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

B8PK46-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
PSLLTENGFC PGCKKSVVDE NGGVVVAFGQ SFFHVDCFKC AKCGNQVTAD
60 70 80 90 100
TNLLLLSDGS PICANCSYSC NVCKLPILDE AIMTGDDSYH AHCFKCKVCK
110 120 130 140 150
NRIDELVFAK TSQGIYCMNC HNQRVARSRR HAQRQREKEQ ERQRERERAA
160 170 180 190 200
AALTAPGTTG ADTSSRRDQT DGAASPASTT TRSPPTALPL SKRPSTAAAA
210 220 230 240 250
EPARSSTYDS SVQSTLGRSV VPSGSRADSL AVPSMSDGSD RSLHSRKSFD
260 270 280 290 300
GGVRPPLRTT PSANSLSTTA SSSSYGLGIP NGETSRKDKR RSINPVMQHG
310 320 330 340 350
SSSTVSSPAN VNPSSFLPSP SSAHDRRPSS PFYDYFTAGH TMSPPTHTDS
360 370 380 390 400
ADFTPFSRMG ASSTRPSTPL STRGSIEHGG QRERTYSGPT PYRSLEQTPR
410 420 430 440 450
GPSRSGPGLP SRPNARTELE LPSRPSSIPT PTSPSHRVDV PHGIESGTDT
460 470 480 490 500
EAESDEHRMT TEPESMLDLP PALPPKDSPS GKAGMRPPLL RLDTADIRRD
510 520 530 540 550
TSDARRLDSE EPTDSPESSP VERTSHATFI APALPPIRIS MGGTDFSELL
560 570 580 590 600
KSVGGNVLKL DQIAETTKEG GRKLDLSAAS PSAFMASNNS AHSRTLGGSS
610 620 630 640 650
HAPSPTSTLD ENNAIRRSLD ALSGRRDSLT SSTHAHIKVT APDHGPEPLR
660 670 680 690 700
TSLSDSLMRQ LQDIVTYAAD EGSPHVVLDL DLAQTLLKLL AEEKDAYNDL
710 720 730 740 750
KRKFDGMRRA SQRYEDGLTV AQTEYDRELK GRRDAEAEVT RLRVLLSGQA
760 770 780 790 800
VRLSAISADT KRQEAQKQLS EELSKNLSDL GRSVSKLKVD RDLVLAEVEQ
810 820 830 840 850
LSASKSSPAV DNEDGAGSFT RALSMRFDNI KNQYQHELLP LTEQREALMR
860 870 880 890 900
EITELKASRE AFLEETTVLN ARNEELAQLN AQYVRRLEAV GLDSSAARND
910 920 930 940 950
TSSQEGSDMT HDRYRQIQNL SSSITSSTVA FTEESAESKF IKVSKPDVTE
960 970 980 990 1000
MPGPQTKAGK FIKWPGHKTP KENLPMVSWP EPFKPKGGKE HAFQQISVLR
1010 1020 1030 1040 1050
VARCDHCGDK MWGSQYRCTG CNFAVHIRCL PHVQSTCSQQ GVNSRDEPSR
1060 1070 1080 1090 1100
PLAPLPPSMF GRDLTEQVRA EARDEPRPIP ILVEKCIEAV DALALDLEGI
1110 1120 1130 1140 1150
YRKTGGSSQV KMITQLFERQ EYRTFDLCDT ERFNDICSVT SVLKTYLRSL
1160 1170 1180 1190 1200
PDPLMTYALH AKFTSAANIR DPEAKSKALL ESVNELPKEH YYTTRALMLH
1210 1220 1230 1240 1250
LHRVSLHADV NRMNARNLGV VFGPTLMRSR DFVNEFGDMA GSTLCMEWLI

ENAPSVF
Length:1,257
Mass (Da):137,563
Last modified:March 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8EE3FB090413E7EA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei1257Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EQ966418 Genomic DNA Translation: EED78754.1

NCBI Reference Sequences

More...
RefSeqi
XP_002476043.1, XM_002475998.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
EED78754; EED78754; POSPLDRAFT_19047

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ppl:POSPLDRAFT_19047

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ966418 Genomic DNA Translation: EED78754.1
RefSeqiXP_002476043.1, XM_002475998.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblFungiiEED78754; EED78754; POSPLDRAFT_19047
KEGGippl:POSPLDRAFT_19047

Phylogenomic databases

HOGENOMiCLU_003874_0_0_1
InParanoidiB8PK46
OMAiLICNNCT

Family and domain databases

CDDicd00029, C1, 1 hit
Gene3Di1.10.555.10, 1 hit
InterProiView protein in InterPro
IPR002219, PE/DAG-bd
IPR008936, Rho_GTPase_activation_prot
IPR000198, RhoGAP_dom
IPR001781, Znf_LIM
PfamiView protein in Pfam
PF00412, LIM, 2 hits
PF00620, RhoGAP, 1 hit
SMARTiView protein in SMART
SM00109, C1, 1 hit
SM00132, LIM, 2 hits
SM00324, RhoGAP, 1 hit
SUPFAMiSSF48350, SSF48350, 1 hit
PROSITEiView protein in PROSITE
PS00478, LIM_DOMAIN_1, 2 hits
PS50023, LIM_DOMAIN_2, 2 hits
PS50238, RHOGAP, 1 hit
PS00479, ZF_DAG_PE_1, 1 hit
PS50081, ZF_DAG_PE_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB8PK46_POSPM
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B8PK46
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 2, 2021
This is version 56 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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