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Entry version 52 (31 Jul 2019)
Sequence version 1 (03 Mar 2009)
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Protein
Submitted name:

ATP-binding cassette transporter, putative

Gene

AFLA_089420

Organism
Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-bindingImported, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ATP-binding cassette transporter, putativeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:AFLA_089420Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri332952 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001875 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:AFLA_089420

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei423 – 445HelicalSequence analysisAdd BLAST23
Transmembranei457 – 475HelicalSequence analysisAdd BLAST19
Transmembranei565 – 586HelicalSequence analysisAdd BLAST22
Transmembranei892 – 909HelicalSequence analysisAdd BLAST18
Transmembranei921 – 942HelicalSequence analysisAdd BLAST22
Transmembranei962 – 989HelicalSequence analysisAdd BLAST28
Transmembranei1001 – 1021HelicalSequence analysisAdd BLAST21
Transmembranei1027 – 1049HelicalSequence analysisAdd BLAST23
Transmembranei1061 – 1081HelicalSequence analysisAdd BLAST21
Transmembranei1154 – 1172HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 132ABC transporterInterPro annotationAdd BLAST124
Domaini293 – 503ABC2_membraneInterPro annotationAdd BLAST211
Domaini516 – 604PDR_CDRInterPro annotationAdd BLAST89
Domaini673 – 814ABC transporterInterPro annotationAdd BLAST142
Domaini868 – 1076ABC2_membraneInterPro annotationAdd BLAST209

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni617 – 639DisorderedSequence analysisAdd BLAST23

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi617 – 631PolyampholyteSequence analysisAdd BLAST15

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000162078

Identification of Orthologs from Complete Genome Data

More...
OMAi
APRWMNQ

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013525 ABC_2_trans
IPR003439 ABC_transporter-like
IPR027417 P-loop_NTPase
IPR010929 PDR_CDR_ABC

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01061 ABC2_membrane, 2 hits
PF00005 ABC_tran, 2 hits
PF06422 PDR_CDR, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B8NK68-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLANRRTGYE EIEGDVWYGS MHHEEAAENY AGQIIMNTEE EIFFPTLTVG
60 70 80 90 100
QTLDFATRLK VPAHLPSNVV NAEAYRAEMK EFLLESLRIP HTAETKVGNE
110 120 130 140 150
YVRGVSGGER KRVSILECLA SGASVYCWDN STRGLDAASA LDWAKMMRTM
160 170 180 190 200
ADVHGSSIIA TLYQAGNDIF RLFDKVLVLD EGKQIYYGPA NEAEQFMESL
210 220 230 240 250
GFECSEGANI GDYLTSVTVP LERRIRSGYE STYPRNAEAI ATSYCKSSAK
260 270 280 290 300
AQMTSEYDYP TSELSQQRTK DFKESVTLEK CRPRSANTVN FATQVRACII
310 320 330 340 350
RQYQVLLGDK KTFAMKQGST LIQALVAGSM YYQVKPDTSG LFLKAGALFW
360 370 380 390 400
SILYNSMSAM SEVVDSFSGR PIVVKHDAFA YCKPAAFCIG QIAADIPITI
410 420 430 440 450
FQITLWSVIL YFMVGLKMSA SAFFTYFVVL FACAMCSTAL FRAVGAVFRT
460 470 480 490 500
FDGASKVSGY VVTIMAMYAG FQIQYTQMRP WFGWLYWLNP VAYAFDGLMS
510 520 530 540 550
NEFRDREIDC TGGNLIPHGE SYASVSMSYR SCAGVRGATP GFASLTGEQY
560 570 580 590 600
LGALSYSYTH LWRNFGILWA WWVFYVVVTI GATMMWKSPS ESGAQLLIPR
610 620 630 640 650
ERLAHHLQLG LDDEESQTPE KYCHGHHSQE KMDGSTPLPT PGAEAHLAKN
660 670 680 690 700
TSIFTWKNLT YTVKTPSGPR VLLDNVHGWV KPGMLGALMG ASGAGKTTLL
710 720 730 740 750
DVLAQRKTDG KIEGSIMVDG RPLSVSFQRS AGYCEQLDVH EPYATVREAL
760 770 780 790 800
EFSALLRQPH NTSEKEKLGY VDVIIDLLEL GDIADTLIGK PNAGGLNIEQ
810 820 830 840 850
RKRVTIGVEL VAKPSRASTI DWRRVWLESP EYQQSLVELD RLIRDTASRE
860 870 880 890 900
SVDNPSSDDN EYATPLWYQT KIVLRRMNIA LFRNTNYVNN KIYLHIGLAL
910 920 930 940 950
FNGFSYWMIG NTVNDMQLRM FTIFVFMFVA PGVVNQLQPL FIERRDIYDA
960 970 980 990 1000
REKKSRMYSW KAFVTALIVS EFPYLCVCGV LYFLCWYYTV GFPAASEKAG
1010 1020 1030 1040 1050
AALFVVVLYE FSYTGIGQFV AAYSPNAVFA ALVNPLLVGI MVSFCGILVP
1060 1070 1080 1090 1100
YDQIIPFWRY WMYYMNPLTY LVGSLLVFNI FDVDVKCADS EFAIFKPPSN
1110 1120 1130 1140 1150
MTCLDYLSSY LEESDANLVN PEARSECRVC PYTSGGGYLK AINLNDYYFG
1160 1170 1180
WRDVGIFVIF IFSSYGLVYL FMKLRTKASK KAES
Length:1,184
Mass (Da):132,918
Last modified:March 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC6D49FBB6744A3B7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EQ963480 Genomic DNA Translation: EED48862.1

NCBI Reference Sequences

More...
RefSeqi
XP_002380763.1, XM_002380722.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
EED48862; EED48862; AFLA_089420

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7918091

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
afv:AFLA_089420

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ963480 Genomic DNA Translation: EED48862.1
RefSeqiXP_002380763.1, XM_002380722.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEED48862; EED48862; AFLA_089420
GeneIDi7918091
KEGGiafv:AFLA_089420

Organism-specific databases

EuPathDBiFungiDB:AFLA_089420

Phylogenomic databases

HOGENOMiHOG000162078
OMAiAPRWMNQ

Family and domain databases

InterProiView protein in InterPro
IPR013525 ABC_2_trans
IPR003439 ABC_transporter-like
IPR027417 P-loop_NTPase
IPR010929 PDR_CDR_ABC
PfamiView protein in Pfam
PF01061 ABC2_membrane, 2 hits
PF00005 ABC_tran, 2 hits
PF06422 PDR_CDR, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB8NK68_ASPFN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B8NK68
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 31, 2019
This is version 52 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health

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