Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA polymerase

Gene

THAPSDRAFT_bd439

Organism
Thalassiosira pseudonana (Marine diatom) (Cyclotella nana)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotation

Cofactori

[4Fe-4S] clusterUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation, DNA-directed DNA polymeraseUniRule annotation, Nucleotidyltransferase, Transferase
Biological processDNA replicationUniRule annotation
Ligand4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymeraseUniRule annotation (EC:2.7.7.7UniRule annotation)
Gene namesi
ORF Names:THAPSDRAFT_bd439Imported
OrganismiThalassiosira pseudonana (Marine diatom) (Cyclotella nana)Imported
Taxonomic identifieri35128 [NCBI]
Taxonomic lineageiEukaryotaStramenopilesBacillariophytaCoscinodiscophyceaeThalassiosirophycidaeThalassiosiralesThalassiosiraceaeThalassiosira
Proteomesi
  • UP000001449 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi35128.Thapsdraft439

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 382DNA_pol_B_exo1InterPro annotationAdd BLAST350
Domaini441 – 902DNA_pol_BInterPro annotationAdd BLAST462
Domaini942 – 1135zf-DNA_PolInterPro annotationAdd BLAST194

Sequence similaritiesi

Belongs to the DNA polymerase type-B family.UniRule annotation

Keywords - Domaini

Zinc-fingerUniRule annotation

Phylogenomic databases

eggNOGiKOG0970 Eukaryota
COG0417 LUCA
HOGENOMiHOG000163524
InParanoidiB8LEG9
KOiK02320
OMAiPKDCIFP

Family and domain databases

Gene3Di1.10.3200.20, 1 hit
3.30.420.10, 1 hit
3.90.1600.10, 2 hits
InterProiView protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR017964 DNA-dir_DNA_pol_B_CS
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR023211 DNA_pol_palm_dom_sf
IPR038256 Pol_alpha_znc_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR015088 Znf_DNA-dir_DNA_pol_B_alpha
PfamiView protein in Pfam
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08996 zf-DNA_Pol, 1 hit
PRINTSiPR00106 DNAPOLB
SMARTiView protein in SMART
SM00486 POLBc, 1 hit
SUPFAMiSSF53098 SSF53098, 2 hits
PROSITEiView protein in PROSITE
PS00116 DNA_POLYMERASE_B, 1 hit

Sequencei

Sequence statusi: Fragment.

B8LEG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QYLDMFWLDA AERNGVVYLY GKVRIPSKDP SKQKYQSCCV TVPNNQRNLF
60 70 80 90 100
VLPRVKSTNP DEGQERYGIM DVYNEIKSVL TPSCIPHTEG SNWAGKKVTR
110 120 130 140 150
SYAFEDPSIP RGECDYLKVK YDGKYPVPNR DVCVNGGKSF EKILGAGASN
160 170 180 190 200
LENFLLKRDL MGPQWVRIYN PKSIGGSISW CKWECTVAGP KSIVKLESVA
210 220 230 240 250
MPPTPTVSTV SIKFKTVVNP KSHKLEIVCV SAICHNKVQL DSASDESTRH
260 270 280 290 300
MTQLTLSNGT MPQFPRDMEK EMKQMPELQK CPNERALLSR LFAQIGQWDP
310 320 330 340 350
DVLVSHNGWG HDIDVLLSRC VELKVSMWSK IGRRRQMKLP NATQFGNGKE
360 370 380 390 400
WAIANALDGR ILCDTCISAK ELLRETTYSL TNLTLTQLKM QRVEIEPVDV
410 420 430 440 450
PKWCRDGKHF VSLAQHTLND AQLVQRLMFK LQILPLTKQL TNIAGNLWAR
460 470 480 490 500
TMKGNRAERN EYLLLHEFHN LKYLVPEKRT AKQRSEELGE EGGASNGKAK
510 520 530 540 550
YSGGLVLEPK KGLYDSFILL LDFNSLYPSL IQEYNLCFTT MEWSKSNAPA
560 570 580 590 600
NVEGGEVPQG DQLPPLPDEG LKRGVLPRVI KTLVDRRRNV KKFLKTEKNA
610 620 630 640 650
EKKEELNIRQ QALKLTANSM YGCLGFSHSR FYAQPIAALV TAMGRETLQR
660 670 680 690 700
TVDLAQTSIG LEVIYGDTDS IMINTRITDV NEYPRVLELG NQVKREVNKL
710 720 730 740 750
YNTLELEIDG VFRSMLLLKK KKYAAVTMAE GPGGKMIFDK EMKGLDLVRR
760 770 780 790 800
DWCIQSKESG KFVLDQILSG EEKEVVVSNI HDHLEKVAQQ MRSGELPLDK
810 820 830 840 850
YIITKGLNKH PNEYPDAKSL PHVYVAKMML KDHKAVSIGD HIPYVITELE
860 870 880 890 900
KEEEPSNKKT LAAERARHPD EIERSNGAMK PDVEWYLTQQ ILPPISRLCE
910 920 930 940 950
PIEGTSPGIL AEKLGLDSSK YNNIVSANID EDDIVDYTPA SCLPDEERFK
960 970 980 990 1000
DVEKLVVTCS GCNESAEFPG VFRLVKENGV SYCASGMSCP NPVCGRPNWG
1010 1020 1030 1040 1050
DADLESCIAK ILNRMNLMKK EQQKLYYDGL VRCDDPMCNL ETRQLSVYEG
1060 1070 1080 1090 1100
CCLKAGCNGR MKTVYTESSL QTQLKYFDSL FDIDHACKQL KKSQSSLTEK
1110 1120 1130 1140
EMLKSLNGAD KDAFQLLHGV SSCSLSKSGY NWVAADFFQS L
Length:1,141
Mass (Da):128,677
Last modified:March 3, 2009 - v1
Checksum:i4C80FEFE15723BAA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei1141Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS999440 Genomic DNA Translation: EED86279.1
RefSeqiXP_002297409.1, XM_002297373.1

Genome annotation databases

EnsemblProtistsiEED86279; EED86279; THAPSDRAFT_bd439
GeneIDi7447729
KEGGitps:THAPSDRAFT_bd439

Similar proteinsi

Entry informationi

Entry nameiB8LEG9_THAPS
AccessioniPrimary (citable) accession number: B8LEG9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 25, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health