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Protein
Submitted name:

Centromere protein K

Gene

cenpk

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-DRE-2467813 Separation of Sister Chromatids
R-DRE-2500257 Resolution of Sister Chromatid Cohesion
R-DRE-5663220 RHO GTPases Activate Formins
R-DRE-606279 Deposition of new CENPA-containing nucleosomes at the centromere

Names & Taxonomyi

Protein namesi
Submitted name:
Centromere protein KImported
Gene namesi
Name:cenpkImported
Synonyms:si:dkey-179o14.3Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 1

Organism-specific databases

ZFINiZDB-GENE-090313-204 cenpk

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000039616 Expressed in 28 organ(s), highest expression level in mature ovarian follicle
ExpressionAtlasiB8JKA0 baseline

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili133 – 160Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IGKP Eukaryota
ENOG4111ZR6 LUCA
GeneTreeiENSGT00390000006243

Family and domain databases

InterProiView protein in InterPro
IPR020993 Centromere_CenpK
PANTHERiPTHR14401 PTHR14401, 1 hit
PfamiView protein in Pfam
PF11802 CENP-K, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

B8JKA0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTPGLPKQIE MEKEVQTSED TGCMSAAKAV LLDECEEQFG LLQKLQNEII
60 70 80 90 100
MADTEAYDDQ SNEAVNRLIA ITSELEQWQE IEPKLLTTNT EVLLAVGKKE
110 120 130 140 150
LQRLHSQLKM VLSCSQAKLD AQKKILKREQ TWQSEKQEAL NSVTEKIARL
160
QQEKQKSDHR KKMKLPTDL
Length:169
Mass (Da):19,338
Last modified:March 3, 2009 - v1
Checksum:iF6D8ED12C7E8C9FD
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B8JK99B8JK99_DANRE
Centromere protein K
cenpk si:dkey-179o14.3
275Annotation score:
A0A2R8PZ46A0A2R8PZ46_DANRE
Centromere protein K
cenpk
274Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573247 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000139828; ENSDARP00000121115; ENSDARG00000039616

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573247 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000139828; ENSDARP00000121115; ENSDARG00000039616

Organism-specific databases

ZFINiZDB-GENE-090313-204 cenpk

Phylogenomic databases

eggNOGiENOG410IGKP Eukaryota
ENOG4111ZR6 LUCA
GeneTreeiENSGT00390000006243

Enzyme and pathway databases

ReactomeiR-DRE-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-DRE-2467813 Separation of Sister Chromatids
R-DRE-2500257 Resolution of Sister Chromatid Cohesion
R-DRE-5663220 RHO GTPases Activate Formins
R-DRE-606279 Deposition of new CENPA-containing nucleosomes at the centromere

Gene expression databases

BgeeiENSDARG00000039616 Expressed in 28 organ(s), highest expression level in mature ovarian follicle
ExpressionAtlasiB8JKA0 baseline

Family and domain databases

InterProiView protein in InterPro
IPR020993 Centromere_CenpK
PANTHERiPTHR14401 PTHR14401, 1 hit
PfamiView protein in Pfam
PF11802 CENP-K, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB8JKA0_DANRE
AccessioniPrimary (citable) accession number: B8JKA0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 10, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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