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Entry version 107 (25 May 2022)
Sequence version 1 (03 Mar 2009)
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Protein
Submitted name:

Adhesion G-protein-coupled receptor V1

Gene

Adgrv1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Adhesion G-protein-coupled receptor V1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Adgrv1Imported
Synonyms:Gpr98Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1274784, Adgrv1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000069170

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei5901 – 5921HelicalSequence analysisAdd BLAST21
Transmembranei5933 – 5952HelicalSequence analysisAdd BLAST20
Transmembranei5972 – 5992HelicalSequence analysisAdd BLAST21
Transmembranei6004 – 6029HelicalSequence analysisAdd BLAST26
Transmembranei6049 – 6073HelicalSequence analysisAdd BLAST25
Transmembranei6100 – 6117HelicalSequence analysisAdd BLAST18
Transmembranei6123 – 6148HelicalSequence analysisAdd BLAST26

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
B8JJE0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000069170, Expressed in liver and 194 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
B8JJE0, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
B8JJE0, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati3251 – 3292EARPROSITE-ProRule annotationAdd BLAST42
Repeati3293 – 3341EARPROSITE-ProRule annotationAdd BLAST49
Repeati3344 – 3389EARPROSITE-ProRule annotationAdd BLAST46
Repeati3391 – 3435EARPROSITE-ProRule annotationAdd BLAST45
Repeati3437 – 3484EARPROSITE-ProRule annotationAdd BLAST48
Repeati3488 – 3530EARPROSITE-ProRule annotationAdd BLAST43
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5846 – 5895GPSInterPro annotationAdd BLAST50
Domaini5898 – 6149G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST252

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni6206 – 6242DisorderedSequence analysisAdd BLAST37
Regioni6264 – 6283DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi6206 – 6233Polar residuesSequence analysisAdd BLAST28
Compositional biasi6264 – 6282Polar residuesSequence analysisAdd BLAST19

Keywords - Domaini

RepeatARBA annotation, SignalARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154880

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_223063_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
QWKAGYP

Database of Orthologous Groups

More...
OrthoDBi
5733at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
B8JJE0

TreeFam database of animal gene trees

More...
TreeFami
TF331149

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.220.50, 1 hit
2.60.40.2030, 35 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026919, ADGRV1
IPR038081, CalX-like_sf
IPR003644, Calx_beta
IPR013320, ConA-like_dom_sf
IPR009039, EAR
IPR005492, EPTP
IPR046338, GAIN_dom_sf
IPR017981, GPCR_2-like
IPR000832, GPCR_2_secretin-like
IPR000203, GPS
IPR006558, LamG-like

The PANTHER Classification System

More...
PANTHERi
PTHR46682, PTHR46682, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00002, 7tm_2, 1 hit
PF03160, Calx-beta, 37 hits
PF03736, EPTP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00237, Calx_beta, 20 hits
SM00560, LamGL, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF141072, SSF141072, 38 hits
SSF49899, SSF49899, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50912, EAR, 6 hits
PS50261, G_PROTEIN_RECEP_F2_4, 1 hit
PS50221, GPS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

B8JJE0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVTSEPGMI SSFLLVYLST LFISFVFGEA EIRFTGQTEF FVNETSTTVI
60 70 80 90 100
RLVIERIGEP ANVTAIVSLS GEDTGDFFDT YAAAFIPARG TNRTVYIAVC
110 120 130 140 150
DDDLPEPDET FTFHLTLQKP SANVKLGWPR AASVTILSND NAFGIISFST
160 170 180 190 200
PSSISVIEPR SRNASVPLTL IREKGTYGMV TVTFDVSGGP NPPEEDLNPV
210 220 230 240 250
RGNITFPPGR ATVIYNVTVL DDEVPENDEL FLIQLRSVEG GAEINASRSS
260 270 280 290 300
VEIIVKKNDS PVNFMQSVYV VPEDDHVLTI PVLRGKDSDG NLIGSDETQV
310 320 330 340 350
SIRYKVMTWD STAHAQQNVD FIDLQPDTTL VFPPFVHESH LKFQIIDDLI
360 370 380 390 400
PEIAESFHIM LLKNTLQGDA VLMGPSTVQV TIKPNDKPYG VLSFNSILFE
410 420 430 440 450
RPVIIDEDTA SSSRFEEIAV VRNGGTHGNV SVSWVLTRNS SDPSPVTADI
460 470 480 490 500
TPASGTLQFA QGQMLAPISL VVFDDDLPEE AEAYLLTILP HTIQGGAEVS
510 520 530 540 550
EPAQLLFYIQ DSDNVYGEIA FFPGESQKIE SSPSERSLSL SLARRGGSKG
560 570 580 590 600
DVRVIYSALY IPAGAMDPLR AKDGILNTSR RSSLLFPEQN QQVSIKLPIR
610 620 630 640 650
NDAFLQNGAH FLVQLEAVVL VNIFPPIPPV SPRFGEIRNI SLLVTPAIAN
660 670 680 690 700
GEIGFLSNLP IILHEPKDSS AEVVSIPLHR DGTDGQATVY WSLRPSGFNS
710 720 730 740 750
KAVTLDDAGP FNGSVVFLSG QNETSINITV KGDDIPELNE TVTLSLDRVS
760 770 780 790 800
VDSDVLKSGY TSRDLIILEN DDPGGIFEFS YDSRGPYVIK EGDAVELRIT
810 820 830 840 850
RSRGSLVKQF LRFHVEPRES NEFYGNMGVL EFTPGEREVV ITLLTRLDGT
860 870 880 890 900
PELDEHFWVI LSSHGERESK LGCATLVNIT ILKNDYPHGI IEFVSDGLSA
910 920 930 940 950
SIKESKGEDI YHAVYGVIRT RGNFGAVNVS WMVSPDFTQD VFPVQGTVCF
960 970 980 990 1000
GDQEFFKNIT VYSLVDEIPE EMEEFTIILL NATGGAQTGI RTTASLRILR
1010 1020 1030 1040 1050
NDDPVYFAEP CVLRVQEGET ANFTVLRNGS VDGACTVQYA TVDGKASGEE
1060 1070 1080 1090 1100
GDFAPVEKGE TLVFEVGSRE QSISVHVKDD GIPETDEPFY IVLFNSTGDT
1110 1120 1130 1140 1150
VVYEYGVATV IIEANDDPNG VFSLEPIDKA VEEGKTNAFW ILRHRGHFGN
1160 1170 1180 1190 1200
VSVAWQLFQN ASLQPGQEFY ETSGTVNFTD GEETKPVILR AFPDRIPEFN
1210 1220 1230 1240 1250
EFYILRLVNI SGPGGQLAET NFQVTVMIPF NDDPFGIFIL DPECLEREVA
1260 1270 1280 1290 1300
EDVLSEDDMS YITSFTILRQ QGVFGDVRVG WEVLSREFTA GLPPMIDFIL
1310 1320 1330 1340 1350
LGSFPSTVPL QPHMRRHHSG TDVLYFSGLE GAFGTVDPKY QPFRNNTIAN
1360 1370 1380 1390 1400
FTFSAWVMPN ANTNGFLIAK DDSHGSIYYG VKIQTNETHV TLSLHYKTFG
1410 1420 1430 1440 1450
SNVTYIAKST VMKYLEEGVW LHVLIILDDG IIEFYLDGKA MPRGIKSLKG
1460 1470 1480 1490 1500
EAITDGPGIL RIGAGMDGGA RFTGWMQDVR TYERKLTPEE IYELHAVPAR
1510 1520 1530 1540 1550
TDLHPISGYL EFRQGESNKS FIVAARDDSE EEGEELFLLK LVSVDGGAQI
1560 1570 1580 1590 1600
SKENTTARLR IQKSDNANGL FGFTGACIPE MTEEGSTVSC VVERTRGALG
1610 1620 1630 1640 1650
YVHVFYTISQ IESEGINYLV DDFANASGTI TFLPWQRSEV LNLYVLDEDM
1660 1670 1680 1690 1700
PELNEYFRVT LVSAVPGDGK LGSTPISGAS IDPEKETTGI TVKASDHPYG
1710 1720 1730 1740 1750
LMQFSTGLPP QPEDSMSLPA SSVPHITVQE EDGEIRLLVI RAQGLLGRVT
1760 1770 1780 1790 1800
VGFRTVSLTA FSPEDYQSTA GTLEFQSGER YKYIFVNITD NSIPELEKSF
1810 1820 1830 1840 1850
KVELLNLDGG VSDLFRVDGS GSGEADTDFF LPPVLPHASL GVASQILVTI
1860 1870 1880 1890 1900
AASDHAHGVF EFSPESLFVS GTEPEDGYST VVLNVTRTRG ALSAVTLQWK
1910 1920 1930 1940 1950
VDSDLDGDLA ITSGNITFET GQRIASITVE ILSDEEPELD KALTVSILNV
1960 1970 1980 1990 2000
SSGSLGVLTN ATLTILASDD PYGVFIFPNK TRPLSVEEAT QNVTLSIIRL
2010 2020 2030 2040 2050
KGLMGEVAVS YATIDDMEKP PYFPPNLARA TQGGDYISAS GLALFRANQT
2060 2070 2080 2090 2100
EATITISILD DAEPERSESV FIELFNSSLV DKVQNRPIPH SPRLGPKVET
2110 2120 2130 2140 2150
VAHLVIVAND DAFGTVQLSA TSVHVAENHV GPIINVTRTG GTFADVSVKF
2160 2170 2180 2190 2200
KAVPITAAAG EDYSIASSDV VLLEGETTKA VPIYIINDIY PELEETFLVQ
2210 2220 2230 2240 2250
LLNETTGGAT LGPLREAVIT IEASDDPYGL FGFQNTKFIV EEPEFNSVRV
2260 2270 2280 2290 2300
NVPIIRNSGT LGNVTVQWVA IINGQFATGD LRVVSGNVTF APGETIQTLL
2310 2320 2330 2340 2350
LEVLADDVPE IEEVVQVQLA AASGGGTIGL DRVANIVIPA NDNPYGSVAF
2360 2370 2380 2390 2400
VQSVFRVQEP LERSSYANIT VRRSGGHFGR LLLCYGTSDI DVVARAVEEG
2410 2420 2430 2440 2450
EDVLSYYESP TQGVPDPLWR TWVNVSAVEE TQYTCATLCL KERACSAFSV
2460 2470 2480 2490 2500
VSGAEGPRCF WMTSWVSGTV NSSDFQTYKK NMTRVASLFS GQAVAGSDYE
2510 2520 2530 2540 2550
PVTRQWAVIL EGDEFANLTV SVLPDDAPEM DESFLISLLE VHLMNISDSF
2560 2570 2580 2590 2600
KNQPTIGHPN TSAVVIGLNG DAFGVFIIYS VSPNTSEDGL CVEVQEQPQT
2610 2620 2630 2640 2650
SVELVIYRTG GSLGQVMVEW RVVGGTATEG LDFMGAGDIL TFAEGETKKM
2660 2670 2680 2690 2700
AILTILDDSE PEDNESILVR LVATEGGSRI LPSSDTVTVN ILANDNVAGI
2710 2720 2730 2740 2750
VSFQTASRSV IGHEGEMLQF HVVRTPPGRG NVTVNWKVVG QNLEVNFANF
2760 2770 2780 2790 2800
TGQLFFSEGT LNKTIFVHLL DDNIPEEKEV YQVVLYDVKT QGVSPAGVAL
2810 2820 2830 2840 2850
LDAQGYAAVL TVEASDEPHG VLNFALSSRF VVLQEANVTI QLFVNREFGS
2860 2870 2880 2890 2900
LGAINVTYAT VPGIVSLKNN TEGNLAEPES DFIPVVGSLV LEEGETTAAI
2910 2920 2930 2940 2950
SITVLEDDIP ELKEYFLVNL THVDLIMAPL TSSPPRLDSE GLTAQIVIDA
2960 2970 2980 2990 3000
NDGAQGMIEW QRNRFEVNET DGVVTLVAQR SRAALGQVSL FMYAQNLEAQ
3010 3020 3030 3040 3050
AGLDYMCTPQ ILHFTDGERF KHVDVMILDD DMPEGDERFQ LLLTNPSPGL
3060 3070 3080 3090 3100
ELGKNTIALI TVLANDDGPG VLSFNNSGHI FLREPTSLYV QESVAVLVIV
3110 3120 3130 3140 3150
REPAQGLFGT VAVQFVVTEV NSSTESKDLS PSKGFIVLEE GVRSKTLRIS
3160 3170 3180 3190 3200
AILDTEPEMD EHFVCTLFNP TGGARLGAHV QTLITIFQNQ APLGLFSISA
3210 3220 3230 3240 3250
VENSATSIDV EESNRSVYLN VSRTNGLDLT ASVQWETVSE TAFGMRGMDV
3260 3270 3280 3290 3300
VFSIFQSFFD KTALDWCFFT VEGSVYGVML RKSSLVVYRW QGTFVPVEDL
3310 3320 3330 3340 3350
KVESPKTCEA FNIGVSPYLV ITHGERSGEK PSINSVYMLT AGFRLVLIQT
3360 3370 3380 3390 3400
IIISGSCQVR HFTSDSQDYF IIASRRNDSE LTQVFRWNGN NFAWHQTLPV
3410 3420 3430 3440 3450
RGVLGMALFS RGGSVFLAIS QANIRQTSLL FTWSGTQFIN FQELPISGIT
3460 3470 3480 3490 3500
QVEALSSGDD VYLCFAKNTF LGNQNAIDIF VWEMGHSSLR YFQSLDFAAV
3510 3520 3530 3540 3550
KRIRSFTPAS GIVHILLTAQ DGSALYCWNS ELNAFSFVLE APAAHDAAFV
3560 3570 3580 3590 3600
TVKSLNSSKT LIALVGATDS HLYELTYVSS QSDFIPSLGE LIFEPGDKEA
3610 3620 3630 3640 3650
IIAVNVLDDT VPEKEESFRV QLKSPRGGAE IGINSSVRVT VLANDGAYGV
3660 3670 3680 3690 3700
VAFAQNSLHK QLEELERDSL VTLNVERLRG THGRITVAWE AAGSVSDVFP
3710 3720 3730 3740 3750
TSGVISFTED QAMSMITLTV LADDLPELSE AVVVTLTQIV TEGVEDPLKG
3760 3770 3780 3790 3800
ATIDQSRSRS VLTILPSDSP YGVVRWHTES LFNRVPEPTE NITVVQLHIV
3810 3820 3830 3840 3850
RDKGLFGDIS IHLIAKPNFL LHINNQATED EDFVLQDSVI IMKENIKETH
3860 3870 3880 3890 3900
AEVAILPDEV PELDEGLIVT IAAVNLVNPN FPAEQPRVQR PRMESAEILI
3910 3920 3930 3940 3950
EENDDPRGIF NFHVVRDVGG VIIAHEGPPP LNVLQVPVVR MAGTFETVNV
3960 3970 3980 3990 4000
YWKATPDSAG LEDFQPSHGM LQFADGQVIA PILVTIIDDS EFELLETFTI
4010 4020 4030 4040 4050
SLVSVTGGGR LGDDVSVNVV IAPNDSPFGI FGFEKKTVMV DGPLLSDDPD
4060 4070 4080 4090 4100
SYVTLTVVRS PGGKGAVRLH WAIEEKAKDD LSPLNGTLYF DETESQKSVI
4110 4120 4130 4140 4150
LHTLKDGMVG EDRRFIIELT AADEVEISPV KGSASVIIRG DKSISEVGIA
4160 4170 4180 4190 4200
SSSRHIIIGE PSATYNGTAI IDLVRGPGVS GEITVNWKIL PPSRGEFVET
4210 4220 4230 4240 4250
SGQLTMLDGQ TAATVVIQAL NDDIPEEKCH YEFQLTEISE GRMLHEASVS
4260 4270 4280 4290 4300
ARITMVASDA PYGRFSFSHE QLHVSEAAQR VNVTVVRSGG SFGRARVLYE
4310 4320 4330 4340 4350
TGSRTAEAGW DFVPASGELL FEAREKMKSL YIDILDDNLP EGPEEFVLAI
4360 4370 4380 4390 4400
TRVDLQGRGY DFTIQENGLQ IDQPPEIGNI SIVRIIIMKN DNAEGIIEFD
4410 4420 4430 4440 4450
PKYTDISVEE DAGVITLPVL RLHGTYGHVS ADFSSRGFSA VPGGYVLHGS
4460 4470 4480 4490 4500
SVTFQHGQNL SFINVSIIDD NGSEFEKQFE ILLIGATGGA ILGRHLVSKI
4510 4520 4530 4540 4550
TIAKSDSPFG IIRFLNQSKI SLPNPSSTMA LHLVLERTGG LLGEIQVSWE
4560 4570 4580 4590 4600
VVGPDAEEPL PPHNGDFADP VSGTVSFGDG EGGVRSIILR VCPHEETEAE
4610 4620 4630 4640 4650
ETFIVQLKPL REAKLDPRAK AVTLTIQKFG DPNGVIHFAP ESLSKRRFSE
4660 4670 4680 4690 4700
PPPSDGPLLV SFLVTRSKGT SGDIKVHWEL SSEFDITRDF LSTRGFFTIA
4710 4720 4730 4740 4750
DGESDASFDV HLLPDDVPEI EEEYAVQLVS VEGGAELDLG KCTARFSVSA
4760 4770 4780 4790 4800
NDDPHGVFAL YSDRQSVLIG QNLDRSIQIN ITRLAGAFGA VAVRVQILSD
4810 4820 4830 4840 4850
NKEDPVATEN EERQLVITDG ARYKVGLVPL KNQVFLSLGS NFTLQLVSVR
4860 4870 4880 4890 4900
LLSGPFYGIP TILQEAKNAI LSVPEEAANS QVGFESAAFQ LMDIKAGTSQ
4910 4920 4930 4940 4950
VMVSRKGTYG RLSVAWTTGY APGSEIPEPI VIGNMTPTLG SLSFVHGEER
4960 4970 4980 4990 5000
KGVLLWTFPS PGRPEAFVLH LSGLRSSAAG GAQLRSGFTT AEIEPMGVFQ
5010 5020 5030 5040 5050
FSPSSRNITV SEDAQTIRIC VQRLFGFHGD LIKVSYETTA GSAKPPEDFE
5060 5070 5080 5090 5100
AVQKGEVFFQ RFQPEIDFEI TIINDQLPEI EETFYINLTS VETRGLGKGG
5110 5120 5130 5140 5150
VNWRPRLNPD LSVAVVTIVD NDDLTGVAVS VPVTAGTVAV DSTLLAMETG
5160 5170 5180 5190 5200
STTHPNKSKI TTIPYTTEVF APVTETVTVS AIPEKLATAH SVISVKPDVV
5210 5220 5230 5240 5250
PGTVLASVYG TLSIGPPIVY VSEEMKNGTL STADILIQRM GGFAGNVTIT
5260 5270 5280 5290 5300
VKTFGGRCAQ KEPSVWPFQD VYGVGNLTTW AFEEEDFEEQ LLTLTFLYGE
5310 5320 5330 5340 5350
RERKIAVQIL DDDEPEGQEF FYVFLTDPQG GAEIVRGKDS TGFSAFAVII
5360 5370 5380 5390 5400
ISGSDLHNGI IGFSEESQRG LELREGADKN SQRLVVTRQP NRAFEEVQIF
5410 5420 5430 5440 5450
WRVTLNQTVT ILQEKGLNLT DELRFVAGVT TCTGGQTRCF IHLELNPKKV
5460 5470 5480 5490 5500
HQVEMPFFVE LYDVTAGAAI NNSARFAPIK LSKSGAPQSL VSFSVGSRLA
5510 5520 5530 5540 5550
VAHKKSTLIS LQVARDSGTG IMMSVNFITQ ELRSAETVGR VLISPAVSGK
5560 5570 5580 5590 5600
DFVRTEGTLV FEPGQKSAVL DVVLTPETGS LNKFPKRFQI VLFDPKGGAR
5610 5620 5630 5640 5650
IDKVYGTANI TLISDADSQA VWGLEDLLHQ PLHEDILNRV LHNLNLRVAT
5660 5670 5680 5690 5700
ESTDEQLSAV MLIMEKITME GRNQAFSIKS RTLLYELLCV LINPKRKDTR
5710 5720 5730 5740 5750
GFSHFVEVAE HFAFSLLTDV TCGSPGEKSK TILDSCPYLS ILALHWNPQQ
5760 5770 5780 5790 5800
INGHKFEGKE GDYIQIPERL LDVPEAEMLD GKNACTLVQF VEYSSQQWFI
5810 5820 5830 5840 5850
AGDNLPALKD KVLSLNVKGQ SAQPLPNNNE VLYRIHAAEP RVVPHTSRCL
5860 5870 5880 5890 5900
LWNQAAASWL SDSQFCKVVE DASDYVECAC SHMSVYAVYA QTDNSSSYNE
5910 5920 5930 5940 5950
AFFSAGLICI SGLCLAVVSH MFCARHSMFA AKLLTHMMVA SLGTQILFLA
5960 5970 5980 5990 6000
SAYASPHLSE ESCSAVAAVA HYLYLCQFSW MLIQSVNFWY VLVVSDEHTE
6010 6020 6030 6040 6050
RRCLLFCLLS WGLPSFVVIL LILILRGIYH RSMPQIYGLI HGDLCFIPNI
6060 6070 6080 6090 6100
YAALFTAALV PLMCLVVVFV VFIHAYQLKP QWKGYDDVFR GRTNAAEIPL
6110 6120 6130 6140 6150
ILYLFALISM TWLWGGLHMA YRHFWMLVLF VIFNSLQGLY VFVVYFILHN
6160 6170 6180 6190 6200
QTCCPMKASY TVEMNGHPGP STAFFTPGSG IPPAGEINKS TQNLINAMEE
6210 6220 6230 6240 6250
VPSDWERSSF QQTSQASPDL KTSPQNGASF PSSGGYGPGS LIADEESQEF
6260 6270 6280 6290
DDLIFALKTG AGLSVSDNES GQGSQEGGTL TDSQIVELRR IPIADTHL
Length:6,298
Mass (Da):687,607
Last modified:March 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA0F39E3765F90270
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8VHN7AGRV1_MOUSE
Adhesion G-protein coupled receptor...
Adgrv1 Gpr98, Kiaa0686, Mass1, Vlgr1
6,298Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8C1E5Q8C1E5_MOUSE
Adhesion G-protein-coupled receptor...
Adgrv1 Gpr98, Mass1
318Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8BPQ5Q8BPQ5_MOUSE
Adhesion G-protein-coupled receptor...
Adgrv1 Gpr98, Mass1
416Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YYF1D3YYF1_MOUSE
Adhesion G-protein-coupled receptor...
Adgrv1
1,218Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5E8P3G5E8P3_MOUSE
Adhesion G-protein-coupled receptor...
Adgrv1
2,238Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6X844F6X844_MOUSE
Adhesion G-protein-coupled receptor...
Adgrv1
533Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
NP_473394.3, NM_054053.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000095585.11; ENSMUSP00000093245.5; ENSMUSG00000069170.15

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
110789

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:110789

UCSC genome browser

More...
UCSCi
uc007rhn.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiNP_473394.3, NM_054053.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiB8JJE0, 1 interactor

Proteomic databases

MaxQBiB8JJE0

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
6556, 130 antibodies from 24 providers

The DNASU plasmid repository

More...
DNASUi
110789

Genome annotation databases

EnsembliENSMUST00000095585.11; ENSMUSP00000093245.5; ENSMUSG00000069170.15
GeneIDi110789
KEGGimmu:110789
UCSCiuc007rhn.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84059
MGIiMGI:1274784, Adgrv1
VEuPathDBiHostDB:ENSMUSG00000069170

Phylogenomic databases

GeneTreeiENSGT00940000154880
HOGENOMiCLU_223063_0_0_1
OMAiQWKAGYP
OrthoDBi5733at2759
PhylomeDBiB8JJE0
TreeFamiTF331149

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
110789, 3 hits in 71 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Adgrv1, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000069170, Expressed in liver and 194 other tissues
GenevisibleiB8JJE0, MM

Family and domain databases

Gene3Di2.60.220.50, 1 hit
2.60.40.2030, 35 hits
InterProiView protein in InterPro
IPR026919, ADGRV1
IPR038081, CalX-like_sf
IPR003644, Calx_beta
IPR013320, ConA-like_dom_sf
IPR009039, EAR
IPR005492, EPTP
IPR046338, GAIN_dom_sf
IPR017981, GPCR_2-like
IPR000832, GPCR_2_secretin-like
IPR000203, GPS
IPR006558, LamG-like
PANTHERiPTHR46682, PTHR46682, 1 hit
PfamiView protein in Pfam
PF00002, 7tm_2, 1 hit
PF03160, Calx-beta, 37 hits
PF03736, EPTP, 1 hit
SMARTiView protein in SMART
SM00237, Calx_beta, 20 hits
SM00560, LamGL, 1 hit
SUPFAMiSSF141072, SSF141072, 38 hits
SSF49899, SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50912, EAR, 6 hits
PS50261, G_PROTEIN_RECEP_F2_4, 1 hit
PS50221, GPS, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB8JJE0_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B8JJE0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 25, 2022
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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