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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei52NucleophileUniRule annotation1
Binding sitei110SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processtRNA processingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciADEH455488:G1GUO-405-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Ordered Locus Names:A2cp1_0410Imported
OrganismiAnaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258)Imported
Taxonomic identifieri455488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeAnaeromyxobacteraceaeAnaeromyxobacter
Proteomesi
  • UP000007089 Componenti: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB8JAV6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 97PseudoU_synth_1InterPro annotationAdd BLAST89
Domaini143 – 245PseudoU_synth_1InterPro annotationAdd BLAST103

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR
OrthoDBiPOG091H010Q

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 2 hits
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

B8JAV6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVVKLVLEY DGTAYVGWQV QPNGPSIQAE VERALATLHK APRRVTAAGR
60 70 80 90 100
TDAGVHARGQ VVSFPEERPL PVKAYVMGMN ALLPPDVAVR AASLAPDGFD
110 120 130 140 150
ARRSARGKRY RYVIENLPTR APLTRLQAWQ HFHPLELANV REAAAHLVGR
160 170 180 190 200
HDFAAFQASD CACEHAVREV RRLDVVGEGG GRIEVVIEAT AFVKHMVRNI
210 220 230 240
VGTLVEVGRG RRAPGSMLDL LARGDRTEAG PTAPPQGLFL EEVFY
Length:245
Mass (Da):26,766
Last modified:March 3, 2009 - v1
Checksum:iD7E4D54BF65B0561
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001359 Genomic DNA Translation: ACL63767.1
RefSeqiWP_012631820.1, NC_011891.1

Genome annotation databases

EnsemblBacteriaiACL63767; ACL63767; A2cp1_0410
KEGGiacp:A2cp1_0410

Similar proteinsi

Entry informationi

Entry nameiB8JAV6_ANAD2
AccessioniPrimary (citable) accession number: B8JAV6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 18, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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