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Protein

Methylglyoxal synthase

Gene

mgsA

Organism
Dictyoglomus turgidum (strain Z-1310 / DSM 6724)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.UniRule annotationSAAS annotation

Catalytic activityi

Glycerone phosphate = methylglyoxal + phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei19SubstrateUniRule annotation1
Binding sitei23SubstrateUniRule annotation1
Active sitei71Proton acceptorUniRule annotation1
Active sitei71Proton donor/acceptorUniRule annotation1
Binding sitei98SubstrateUniRule annotation1

GO - Molecular functioni

  • methylglyoxal synthase activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

BioCyciDTUR515635:G1GU5-867-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Methylglyoxal synthaseUniRule annotationSAAS annotation (EC:4.2.3.3UniRule annotationSAAS annotation)
Short name:
MGSUniRule annotation
Gene namesi
Name:mgsAUniRule annotation
Ordered Locus Names:Dtur_0861Imported
OrganismiDictyoglomus turgidum (strain Z-1310 / DSM 6724)Imported
Taxonomic identifieri515635 [NCBI]
Taxonomic lineageiBacteriaDictyoglomiDictyoglomalesDictyoglomaceaeDictyoglomus
Proteomesi
  • UP000007719 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: GO_Central

Interactioni

Protein-protein interaction databases

STRINGi515635.Dtur_0861

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 118MGSInterPro annotationAdd BLAST94

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni45 – 48Substrate bindingUniRule annotation4
Regioni65 – 66Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the methylglyoxal synthase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4108Z5K Bacteria
COG1803 LUCA
HOGENOMiHOG000283729
InParanoidiB8E059
KOiK01734
OMAiRACDVHN
OrthoDBiPOG091H04UH

Family and domain databases

CDDicd01422 MGS, 1 hit
Gene3Di3.40.50.1380, 1 hit
HAMAPiMF_00549 Methylglyoxal_synth, 1 hit
InterProiView protein in InterPro
IPR004363 Methylgl_synth
IPR018148 Methylglyoxal_synth_AS
IPR011607 MGS-like_dom
IPR036914 MGS-like_dom_sf
PANTHERiPTHR30492 PTHR30492, 1 hit
PfamiView protein in Pfam
PF02142 MGS, 1 hit
PIRSFiPIRSF006614 Methylglyox_syn, 1 hit
SMARTiView protein in SMART
SM00851 MGS, 1 hit
SUPFAMiSSF52335 SSF52335, 1 hit
TIGRFAMsiTIGR00160 MGSA, 1 hit
PROSITEiView protein in PROSITE
PS01335 METHYLGLYOXAL_SYNTH, 1 hit

Sequencei

Sequence statusi: Complete.

B8E059-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGYREIIMGK QKRIALVAHD NKKQELLEWA KFNKGTLANH ILYATGTTGD
60 70 80 90 100
IIERELGLKV IKFYSGPLGG DQQIGAKIAE GEIDFLIFFW DPLEPLPHDP
110 120 130 140 150
DVKALLRIAV VWNIPIASNR ATADFIISSP LMNTEYVRLV PDYQGYIHRK

INL
Length:153
Mass (Da):17,332
Last modified:March 3, 2009 - v1
Checksum:iE9F9E0C618F754B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001251 Genomic DNA Translation: ACK42142.1
RefSeqiWP_012583226.1, NC_011661.1
YP_002352756.1, NC_011661.1

Genome annotation databases

EnsemblBacteriaiACK42142; ACK42142; Dtur_0861
GeneIDi7082814
KEGGidtu:Dtur_0861
PATRICifig|515635.4.peg.900

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001251 Genomic DNA Translation: ACK42142.1
RefSeqiWP_012583226.1, NC_011661.1
YP_002352756.1, NC_011661.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi515635.Dtur_0861

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACK42142; ACK42142; Dtur_0861
GeneIDi7082814
KEGGidtu:Dtur_0861
PATRICifig|515635.4.peg.900

Phylogenomic databases

eggNOGiENOG4108Z5K Bacteria
COG1803 LUCA
HOGENOMiHOG000283729
InParanoidiB8E059
KOiK01734
OMAiRACDVHN
OrthoDBiPOG091H04UH

Enzyme and pathway databases

BioCyciDTUR515635:G1GU5-867-MONOMER

Family and domain databases

CDDicd01422 MGS, 1 hit
Gene3Di3.40.50.1380, 1 hit
HAMAPiMF_00549 Methylglyoxal_synth, 1 hit
InterProiView protein in InterPro
IPR004363 Methylgl_synth
IPR018148 Methylglyoxal_synth_AS
IPR011607 MGS-like_dom
IPR036914 MGS-like_dom_sf
PANTHERiPTHR30492 PTHR30492, 1 hit
PfamiView protein in Pfam
PF02142 MGS, 1 hit
PIRSFiPIRSF006614 Methylglyox_syn, 1 hit
SMARTiView protein in SMART
SM00851 MGS, 1 hit
SUPFAMiSSF52335 SSF52335, 1 hit
TIGRFAMsiTIGR00160 MGSA, 1 hit
PROSITEiView protein in PROSITE
PS01335 METHYLGLYOXAL_SYNTH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB8E059_DICTD
AccessioniPrimary (citable) accession number: B8E059
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 7, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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