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Entry version 59 (07 Oct 2020)
Sequence version 1 (03 Mar 2009)
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Protein
Submitted name:

Ankrd11 protein

Gene

Ankrd11

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ankrd11 proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ankrd11Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1924337, Ankrd11

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
B7ZWM7

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini127 – 240ANK_REP_REGIONInterPro annotationAdd BLAST114
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati133 – 165ANKPROSITE-ProRule annotationAdd BLAST33
Repeati166 – 198ANKPROSITE-ProRule annotationAdd BLAST33
Repeati199 – 231ANKPROSITE-ProRule annotationAdd BLAST33

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni29 – 54DisorderedSequence analysisAdd BLAST26
Regioni94 – 136DisorderedSequence analysisAdd BLAST43
Regioni255 – 331DisorderedSequence analysisAdd BLAST77
Regioni389 – 470DisorderedSequence analysisAdd BLAST82
Regioni483 – 617DisorderedSequence analysisAdd BLAST135
Regioni693 – 771DisorderedSequence analysisAdd BLAST79
Regioni884 – 928DisorderedSequence analysisAdd BLAST45
Regioni943 – 1003DisorderedSequence analysisAdd BLAST61
Regioni1017 – 1040DisorderedSequence analysisAdd BLAST24
Regioni1080 – 1354DisorderedSequence analysisAdd BLAST275
Regioni1386 – 1677DisorderedSequence analysisAdd BLAST292
Regioni1829 – 1866DisorderedSequence analysisAdd BLAST38
Regioni1947 – 1993DisorderedSequence analysisAdd BLAST47
Regioni2077 – 2352DisorderedSequence analysisAdd BLAST276

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi32 – 54PolyampholyteSequence analysisAdd BLAST23
Compositional biasi94 – 122PolarSequence analysisAdd BLAST29
Compositional biasi268 – 286PolarSequence analysisAdd BLAST19
Compositional biasi416 – 431BasicSequence analysisAdd BLAST16
Compositional biasi483 – 502PolarSequence analysisAdd BLAST20
Compositional biasi519 – 553PolarSequence analysisAdd BLAST35
Compositional biasi598 – 613BasicSequence analysisAdd BLAST16
Compositional biasi1102 – 1267PolyampholyteSequence analysisAdd BLAST166
Compositional biasi1268 – 1285PolarSequence analysisAdd BLAST18
Compositional biasi1290 – 1354PolyampholyteSequence analysisAdd BLAST65
Compositional biasi1386 – 1410PolyampholyteSequence analysisAdd BLAST25
Compositional biasi1419 – 1504PolyampholyteSequence analysisAdd BLAST86
Compositional biasi1513 – 1530PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1544 – 1558PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1565 – 1603PolyampholyteSequence analysisAdd BLAST39
Compositional biasi1644 – 1664PolarSequence analysisAdd BLAST21
Compositional biasi2139 – 2154Pro-richSequence analysisAdd BLAST16
Compositional biasi2269 – 2283PolyampholyteSequence analysisAdd BLAST15
Compositional biasi2316 – 2331PolyampholyteSequence analysisAdd BLAST16
Compositional biasi2337 – 2352PolarSequence analysisAdd BLAST16

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, RepeatARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR042636, ANKRD11
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf

The PANTHER Classification System

More...
PANTHERi
PTHR24145, PTHR24145, 3 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023, Ank, 1 hit
PF12796, Ank_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403, SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B7ZWM7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESRRTRTQM PPAQSMLWYC KAGTVLEAPW HEMEVPRSKK KEKQGPERKR
60 70 80 90 100
IKKEPVARKS GLLFGMGLSG IRAGYPLSER QQVALLMQMT AEESANSPVD
110 120 130 140 150
TTPKHPSQST VCQKGTPNSA SKTKDKVNKR NERGETRLHR AAIRGDARRI
160 170 180 190 200
KELISEGADV NVKDFAGWTA LHEACNRGYY DIAKQLLAAG AEVNTKGLDD
210 220 230 240 250
DTPLHDAANN GHYKVVKLLL RYGGNPQQSN RKGETPLKVA NSPTMVNLLL
260 270 280 290 300
GKGTYTSSEE SSTESSEEED APSFAPSSSV DGNNTDSEFE KGLKLKAKNP
310 320 330 340 350
EPQKTVTPVK DEYEFDEDDE QDRVPPVDDK HLLKKDYRKE AKANSFISIP
360 370 380 390 400
KMEVKSYSKN NTLAPKKAAH RILSDTSDEE DVSVSIGAGE KLRLSAHTML
410 420 430 440 450
PGSKARESSS SRQQKEKNKL KKKRKKETKG KEVRFGKRSD KFCSSGSESE
460 470 480 490 500
SSESEEDDGD SVGSSGCLKG SPLVLKDPSL FSSLSASSTS SHGSAVAQKH
510 520 530 540 550
GSGHTDQHTK HWRTDNWKAI SSPAWSEVSS LSDSSRTGLT SESDCSSEGS
560 570 580 590 600
SVESLKPTRR KQEHRKRGVL QSAPSEKRSS FHPCTDGAVP KLDKEGKVVK
610 620 630 640 650
KHKTKHKHKH KEKGQCSVSQ ELKLKSFTYE YEDSKQKSDK AILLESDLST
660 670 680 690 700
ENKLKVLKHD REHLKKEDKL GRMKPEDKDW LFKDEKVLKR IKDANKDMSR
710 720 730 740 750
AFREDKDRAS KAERERATKD KSPKEEKLRL YKEERKKKSK DRASRLERKN
760 770 780 790 800
DMKEDKLSKE KEKAFKEDKE KLKKEKLYRE DAAFDDYCNK SQFLDHEDTK
810 820 830 840 850
FSLSDDQQKR WFSDLSDSSF DFKGEDSWDS VTDYRDIKND SVAKLILETV
860 870 880 890 900
KEDSKEKKRD NKIREKRDFK DSFFRKRDRD CLDKNSEKRR DQTEKHKSIP
910 920 930 940 950
SYLSEKDKKR RESAEGGRDR RDGRIRSEEV HREDLKECGF ESSFKDKSDC
960 970 980 990 1000
DFPKNLEPWE RPHAAREKEK KDALEKERKE KGRADKYKEK SSERERSDKS
1010 1020 1030 1040 1050
TLDKCQKDKE FEKCFKEKKD GKEKHKDIHS KDRKASFDQL REKKEKVFSS
1060 1070 1080 1090 1100
IISEDFSERK DDRKGKEKSW YIADIFTDES EDEKDDCVAG SFKATEASDT
1110 1120 1130 1140 1150
QRVDGLPEKE EGREHPSDRH RKSSSDRQHT EKPRDKEPKE KKKDRGASEG
1160 1170 1180 1190 1200
GKDKKEKMEK IFEKHKEKKD KECAERYKDR KERASADSAP EKKNKQKLPE
1210 1220 1230 1240 1250
KVEKKHFAED KVKSKHKEKP EKEHSRERER KPSRGPDVEK SLLEKLEEEA
1260 1270 1280 1290 1300
LHDYREDSND KISEVSSDSF ADHGQEPSLS TLLEVSFSEP PAEDKARDSA
1310 1320 1330 1340 1350
CLSEKLREKE RHRHSSSSSK KSHERERAKK EKAEKKEKSE DYKDSISSVR
1360 1370 1380 1390 1400
KDASQFEKDF LDAETYGVSY PTKADVEEEL DKAIELFSSE KKDRSDPERE
1410 1420 1430 1440 1450
PAKRIEKELK PYGSSAISIL KEKKKREKHR ERWREEKERH RDKHVDGFLR
1460 1470 1480 1490 1500
HHKDEPKPAA KDKDNPPNSF KEKSREESLK LSETKLKEKF KENTEREKGD
1510 1520 1530 1540 1550
SIKMSNGNDK LVPSRDSGKK DSRPREKLLG DGDLMMTSFE RMLSQKDLEI
1560 1570 1580 1590 1600
EERHKRHKER MKQMEKMRHR SGDPKLKEKK PTEDGRKKSL DFPSKKALGL
1610 1620 1630 1640 1650
DKKVKEPAPT LTTGESKPHS GPGTESKDWL SGQPLKEVLP ASPRTEQSRP
1660 1670 1680 1690 1700
TGVPTPTSVV SCPSYEEVMH TPRTPSCSAD DYPDLVFDCT DSQHSMPVST
1710 1720 1730 1740 1750
ASTSACSPPF FDRFSVASSV VSENAAGQTP TRPISTNLYR SISVDIRRTP
1760 1770 1780 1790 1800
EEEFSAGDKL FRQQSVPAPS SFDSPVQHLL EEKAPLPPVP AEKFACLSPG
1810 1820 1830 1840 1850
YYSPDYGIPS PKVDTLHCPP TAVVSATPPP DSVFSNLPPK SSPSPRGELL
1860 1870 1880 1890 1900
SPAIEGTLPP DLGLPLDATE DQQATAAILP QEPSYLEPLD EGPFTTVITE
1910 1920 1930 1940 1950
EPVEWTHTAA EQGLSSSSLI ASASENPVSW PVGSELMLKS PQRFAESPKH
1960 1970 1980 1990 2000
FCPGESLHST TPGPYSAAEP TYPVSPGSYP LPAPEPALEE VKDGGTGAIP
2010 2020 2030 2040 2050
VAISAAEGAA PYAAPARLES FFSNCKSHPD APLDTAPEPT GVTAVAQVEA
2060 2070 2080 2090 2100
LGPLESSFLD SNPSISTLSQ VEPVSWHEAF TSPEDDLDLG PFSLPELPLQ
2110 2120 2130 2140 2150
AKDASDVEAE AAKASPVPPA ESPPGPTGVL GGGDVPAPAA EEPPAPPPQE
2160 2170 2180 2190 2200
ASPQLSIEPE PSEEPKLDVV LEATVETEVL ADDSAPEASI SNSVPAPSPP
2210 2220 2230 2240 2250
QQQPPGGGDE EAETEDPSAT PCCAPDGPTT DGLAQAHNSA EASCVVAAAE
2260 2270 2280 2290 2300
GPPGNVQAEA TDPEPKPTSE VPKAPKVEEV PQRMTRNRAQ MLASQSKQGI
2310 2320 2330 2340 2350
PAAEKDPMPT PASRAKGRAS EEEDAQAQHP RKRRFQRSSQ QLQQQLNTST
2360 2370 2380 2390 2400
QQTREVIQQT LAAIVDAIKL DAIEPYHSDR SNPYFEYLQI RKKIEEKRKI
2410 2420 2430 2440 2450
LCCITPQAPQ CYAEYVTYTG SYLLDGKPLS KLHIPVIAPP PSLAEPLKEL
2460 2470 2480 2490 2500
FKQQEAVRGK LRLQHSIERE KLIVSCEQEI LRVHCRAART IANQAVPFSA
2510 2520 2530 2540 2550
CTMLLDSEVY NMPLESQGDE NKSVRDRFNA RQFISWLQDV DDKYDRMKTC
2560 2570 2580 2590 2600
LLMRQQHEAA ALNAVQRMEW QLKAQELDPA GHKSLCVNEV PSFYVPMVDV

NDDFVLLPA
Length:2,609
Mass (Da):292,805
Last modified:March 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i48457BDB1058E69A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC172141 mRNA Translation: AAI72141.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC172141 mRNA Translation: AAI72141.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PeptideAtlasiB7ZWM7

Organism-specific databases

MGIiMGI:1924337, Ankrd11

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ankrd11, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR042636, ANKRD11
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
PANTHERiPTHR24145, PTHR24145, 3 hits
PfamiView protein in Pfam
PF00023, Ank, 1 hit
PF12796, Ank_2, 1 hit
SMARTiView protein in SMART
SM00248, ANK, 3 hits
SUPFAMiSSF48403, SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB7ZWM7_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B7ZWM7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 7, 2020
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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