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Protein
Submitted name:

ZFP57 protein

Gene

ZFP57

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
ZFP57 proteinImported
Gene namesi
Name:ZFP57Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134937821

PTM / Processingi

Proteomic databases

PRIDEiB7ZW61

Expressioni

Gene expression databases

GenevisibleiB7ZW61 HS

Structurei

3D structure databases

ProteinModelPortaliB7ZW61
SMRiB7ZW61
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 116KRABInterPro annotationAdd BLAST73
Domaini175 – 202C2H2-typeInterPro annotationAdd BLAST28
Domaini203 – 230C2H2-typeInterPro annotationAdd BLAST28
Domaini231 – 258C2H2-typeInterPro annotationAdd BLAST28
Domaini259 – 286C2H2-typeInterPro annotationAdd BLAST28
Domaini384 – 411C2H2-typeInterPro annotationAdd BLAST28
Domaini412 – 439C2H2-typeInterPro annotationAdd BLAST28
Domaini440 – 467C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
HOGENOMiHOG000155778
HOVERGENiHBG108764
KOiK09228

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 7 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 7 hits

Sequencei

Sequence statusi: Complete.

B7ZW61-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFEQLKPIEP VQKTLPWVGE VAATLQEAMK RDCWREARVK KKPVTFEDVA
60 70 80 90 100
VNFTQEEWDC LDASQRVLYQ DVMSETFKNL TSVARIFLHK PELITKLEQE
110 120 130 140 150
EEQWREFVHL PNTEGLSEGK KKELREQHPS LRDEGTSDDK VFLACRGAGQ
160 170 180 190 200
CPLSAPAGTM DRTRVLQASQ AGPPFFCYTC DKCFSRRSYL YSHQFVHNPK
210 220 230 240 250
LTNSCSQCGK LFRSPKSLSY HRRMHLGERP FCCTLCDKTY CDASGLSRHR
260 270 280 290 300
RVHLGYRPHS CSVCGKSFRD QSELKRHQKI HQNQEPVDGN QECTLRIPGT
310 320 330 340 350
QAEFQTPIAR SQGSIQGLLD VNHAPVARSQ EPIFRTEGPM AQNQASVLKN
360 370 380 390 400
QAPVTRTQAP ITGTLCQDAR SNSHPVKPSR LNVFCCPHCS LTFSKKSYLS
410 420 430 440 450
RHQKAHLTEP PNYCFHCSKS FSSFSRLVRH QQTHWKQKSY LCPICDLSFG
460 470 480 490 500
EKEGLMDHWR GYKGKDLCQS SHHKCRVILG QWLGFSHDVP TMAGEEWKHG
510 520 530
GDQSPPRIHT PRRRGLREKA CKGDKTKEAV SILKHK
Length:536
Mass (Da):61,317
Last modified:March 3, 2009 - v1
Checksum:i6321DDFF0A6ED77B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC171888 mRNA Translation: AAI71888.1
RefSeqiNP_001103279.2, NM_001109809.2
UniGeneiHs.156326

Genome annotation databases

GeneIDi346171
KEGGihsa:346171

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC171888 mRNA Translation: AAI71888.1
RefSeqiNP_001103279.2, NM_001109809.2
UniGeneiHs.156326

3D structure databases

ProteinModelPortaliB7ZW61
SMRiB7ZW61
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB7ZW61

Protocols and materials databases

DNASUi346171
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi346171
KEGGihsa:346171

Organism-specific databases

CTDi346171
PharmGKBiPA134937821

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
HOGENOMiHOG000155778
HOVERGENiHBG108764
KOiK09228

Miscellaneous databases

GenomeRNAii346171

Gene expression databases

GenevisibleiB7ZW61 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 7 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 7 hits
ProtoNetiSearch...

Entry informationi

Entry nameiB7ZW61_HUMAN
AccessioniPrimary (citable) accession number: B7ZW61
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 10, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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