Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 54 (17 Jun 2020)
Sequence version 1 (03 Mar 2009)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Bromodomain adjacent to zinc finger domain protein 2A

Gene

baz2a

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi541 – 553A.T hook 1Add BLAST13
DNA bindingi541 – 553A.T hook 2Add BLAST13
DNA bindingi1204 – 1216A.T hook 3Add BLAST13
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri1476 – 1526PHD-typePROSITE-ProRule annotationAdd BLAST51

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, DNA-binding, Repressor, RNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Bromodomain adjacent to zinc finger domain protein 2A
Alternative name(s):
Transcription termination factor I-interacting protein 5
Short name:
TTF-I-interacting protein 5
Short name:
Tip5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:baz2a
Synonyms:tip5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus laevis (African clawed frog)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8355 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-965905 baz2a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003831491 – 1698Bromodomain adjacent to zinc finger domain protein 2AAdd BLAST1698

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
B7ZS37

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the NoRC complex, at least composed of SMARCA5/SNF2H and BAZ2A/TIP5.

By similarity

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
B7ZS37

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini418 – 489MBDPROSITE-ProRule annotationAdd BLAST72
Domaini701 – 766DDTPROSITE-ProRule annotationAdd BLAST66
Domaini1602 – 1672BromoPROSITE-ProRule annotationAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili579 – 638Sequence analysisAdd BLAST60

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The MBD (methyl-CpG-binding) domain, also named TAM domain, specifically recognizes and binds a conserved stem-loop structure the association within pRNA.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the WAL family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1476 – 1526PHD-typePROSITE-ProRule annotationAdd BLAST51

Keywords - Domaini

Bromodomain, Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K15224

Family and domain databases

Conserved Domains Database

More...
CDDi
cd05503 Bromo_BAZ2A_B_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.920.10, 1 hit
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037374 BAZ2A/B_Bromo
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR018501 DDT_dom
IPR016177 DNA-bd_dom_sf
IPR001739 Methyl_CpG_DNA-bd
IPR028940 TIP5
IPR028941 WHIM2_dom
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD

The PANTHER Classification System

More...
PANTHERi
PTHR45915:SF5 PTHR45915:SF5, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00439 Bromodomain, 1 hit
PF02791 DDT, 1 hit
PF01429 MBD, 1 hit
PF00628 PHD, 1 hit
PF15613 WSD, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00503 BROMODOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00297 BROMO, 1 hit
SM00571 DDT, 1 hit
SM00391 MBD, 1 hit
SM00249 PHD, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47370 SSF47370, 1 hit
SSF54171 SSF54171, 1 hit
SSF57903 SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit
PS50827 DDT, 1 hit
PS50982 MBD, 1 hit
PS50016 ZF_PHD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B7ZS37-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METQNHLSCT GQTPLTNASG LKLLPQSVEP VYTNSTLTSF SQHGKVLNYD
60 70 80 90 100
LPVNGLISPS LSNNAHGTLL SNEHITHNSA SNNFDYLWKK PKSSVHKDSH
110 120 130 140 150
VSNQFLVNGS TCPITNGPSI KRSPQETLGN CTSNQTASFN VSSHSVCSPN
160 170 180 190 200
EANVKMVTAA NGAHYGFYEA SLPVSVSASN MQSVSGDNLV KERTVEENEA
210 220 230 240 250
GATEERNHTP ELAEALEPSD TQTDLNICEY KESVLDPVIQ STPNPLLPPD
260 270 280 290 300
VSNLDDPSQL PSQLGDSHLL NEDSLEPFGA DLIQDPISST MYDLEELEVG
310 320 330 340 350
STKQKDPQLD TSSLDCPTYS LSAAFPLVAE DTNDSSVLFN ASSASPVLGD
360 370 380 390 400
SVMQESASEM GEDPEGSKAE EPVSGPENVS QDEMTIENTS PEPCVAAEHE
410 420 430 440 450
EEELEPGEVK GTISRRRIAT PEQVCFPLQH GWRREVRIKK GSHRWQGETW
460 470 480 490 500
YYAPCGKRMK QFPEVIKYLS KNAGPFVRRE HFSFSPRMPV GDFYEERNTA
510 520 530 540 550
EGLQWVLLNS EEIPSRIIAI TGKRGRPRNL EKAKAKEQKA KRGRGRPPKV
560 570 580 590 600
KMIDLLSKAD AKLLRKLENQ DILSDSEKVQ LCKLKKKMRR KARNQEAKLE
610 620 630 640 650
AAKKLKEIKE KEEKKQKIQK AKNQEKAKNQ EKKRTRRQPK QKAPVVQKPD
660 670 680 690 700
RKLLAQQRRL EERKRQQFIL EELKKPTEDM CLPDHQQLPD FPCVPGLFLP
710 720 730 740 750
SCAFSDCLTT VEFLHSYGKV LGLDEAKDIP SLCTLQEGLF NVGDSLGEVQ
760 770 780 790 800
DLLVKLLQAA MINPGLPPYC QSLKILGEKV SEIVLSRENV SEPLRIFLEA
810 820 830 840 850
YGGDIELCDS LRSHPFQAHA PHIKTAILAF IVNELNASSL IISEIDKTLE
860 870 880 890 900
NMSHYRKHKW IIEGKIRRLK FALSKRKSSE ESQITTTEVS LRRRSERNAE
910 920 930 940 950
ENDELDSIDE SAIQKDYVQE EVDIPPSTSV VELERQIEKL TKRQMFFRKK
960 970 980 990 1000
ILGSSQRLRT VCLGQDRYRR CYWMLPHLGG IFIEGLPESA EPTEEAALGN
1010 1020 1030 1040 1050
DIEASSVKTE DKSFGSLCKT SGHPRNSTAE PEQNSTSCHC SDSKDKEPSG
1060 1070 1080 1090 1100
VTDQFPNSVP LTNNQQDLSQ SVFLSWLTKN QTSIMDSTVL TPESSPPHSE
1110 1120 1130 1140 1150
STPIISSEAT EKPEQWLPLI SRTPCRNHNQ GLSTHSSNRL SPPSPTAATS
1160 1170 1180 1190 1200
VKQVNEFTEE AQTFATSLPS NSTPCHVCYN SGKSSTASHE ITLTSNILHD
1210 1220 1230 1240 1250
SEKEKRRGRR PSKLLKQIEQ KYYNQLIERP IPAGVRQKWW WIKDPAMLES
1260 1270 1280 1290 1300
LLKALHPRGI REKTLHKHLT KHLQHLKEMC ARPASDALFK FTPVDGHRVS
1310 1320 1330 1340 1350
QETLDRWSVT DLTFQVDLSA LQWVEDLEQR VMLSDLQQRG WSPSAPDSVR
1360 1370 1380 1390 1400
TDLKYYEHQL EPADDITVKV KREDCRLYRE SSNPLDLAVL RILCLEENVE
1410 1420 1430 1440 1450
RKYLKEPLWL FSEVQHEKVV ITNPEDPLST TEIEYSITSR LRLWRQTVER
1460 1470 1480 1490 1500
CRSAAQLSLC LQQLERSIAW ERSLNKVTCL YCRKGDNDEL LLLCDSCDRG
1510 1520 1530 1540 1550
CHTYCHRPRM NEIPEGDWFC PTCISLQSES EFLRSSGSSK RIRKCTVRFT
1560 1570 1580 1590 1600
EDSPSKPSRR REHPTASQFS PGESPASKKR RMGTRSQSPD LTFCEIILME
1610 1620 1630 1640 1650
LESHEDAWPF LEPVNPRLVP GYRKIIKNPM DFSTMRHKLL NGNYSRCEEF
1660 1670 1680 1690
AEDAELIFSN CQLFNEDESD VGKAGLILKK FYDARWEEFS QERNQISL
Length:1,698
Mass (Da):192,095
Last modified:March 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4D58AB30632A88AE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti653L → Q in AAN61105 (Ref. 1) Curated1
Sequence conflicti661E → K in AAN61105 (Ref. 1) Curated1
Sequence conflicti741N → K in AAN61105 (Ref. 1) Curated1
Sequence conflicti806E → Q in AAN61105 (Ref. 1) Curated1
Sequence conflicti966D → Y in AAN61105 (Ref. 1) Curated1
Sequence conflicti1210R → P in AAN61105 (Ref. 1) Curated1
Sequence conflicti1268H → Y in AAN61105 (Ref. 1) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY145834 mRNA Translation: AAN61105.1
BC170384 mRNA Translation: AAI70384.1
BC170386 mRNA Translation: AAI70386.1

NCBI Reference Sequences

More...
RefSeqi
NP_001082767.1, NM_001089298.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
398712

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
xla:398712

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY145834 mRNA Translation: AAN61105.1
BC170384 mRNA Translation: AAI70384.1
BC170386 mRNA Translation: AAI70386.1
RefSeqiNP_001082767.1, NM_001089298.1

3D structure databases

SMRiB7ZS37
ModBaseiSearch...

Proteomic databases

PRIDEiB7ZS37

Genome annotation databases

GeneIDi398712
KEGGixla:398712

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
398712
XenbaseiXB-GENE-965905 baz2a

Phylogenomic databases

KOiK15224

Family and domain databases

CDDicd05503 Bromo_BAZ2A_B_like, 1 hit
Gene3Di1.20.920.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR037374 BAZ2A/B_Bromo
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR018501 DDT_dom
IPR016177 DNA-bd_dom_sf
IPR001739 Methyl_CpG_DNA-bd
IPR028940 TIP5
IPR028941 WHIM2_dom
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR45915:SF5 PTHR45915:SF5, 2 hits
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PF02791 DDT, 1 hit
PF01429 MBD, 1 hit
PF00628 PHD, 1 hit
PF15613 WSD, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00297 BROMO, 1 hit
SM00571 DDT, 1 hit
SM00391 MBD, 1 hit
SM00249 PHD, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
SSF54171 SSF54171, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit
PS50827 DDT, 1 hit
PS50982 MBD, 1 hit
PS50016 ZF_PHD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBAZ2A_XENLA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B7ZS37
Secondary accession number(s): Q6YI94
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: March 3, 2009
Last modified: June 17, 2020
This is version 54 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again