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Entry version 95 (02 Jun 2021)
Sequence version 1 (03 Mar 2009)
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Protein

Fibronectin

Gene

Fn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHeparin-bindingARBA annotation
Biological processAcute phaseARBA annotation, Cell adhesionARBA annotation, Cell shapeARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
FibronectinARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Fn1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:95566, Fn1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501508744028 – 2176FibronectinSequence analysisAdd BLAST2149

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi360 ↔ 386PROSITE-ProRule annotation
Disulfide bondi374 ↔ 401PROSITE-ProRule annotation
Disulfide bondi420 ↔ 446PROSITE-ProRule annotation
Disulfide bondi434 ↔ 461PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation, OxidationARBA annotation

Proteomic databases

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
328850

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000026193, Expressed in vault of skull and 334 other tissues

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini51 – 91Fibronectin type-IInterPro annotationAdd BLAST41
Domaini96 – 139Fibronectin type-IInterPro annotationAdd BLAST44
Domaini140 – 183Fibronectin type-IInterPro annotationAdd BLAST44
Domaini185 – 229Fibronectin type-IInterPro annotationAdd BLAST45
Domaini230 – 274Fibronectin type-IInterPro annotationAdd BLAST45
Domaini306 – 345Fibronectin type-IInterPro annotationAdd BLAST40
Domaini355 – 403Fibronectin type-IIInterPro annotationAdd BLAST49
Domaini415 – 463Fibronectin type-IIInterPro annotationAdd BLAST49
Domaini468 – 511Fibronectin type-IInterPro annotationAdd BLAST44
Domaini516 – 558Fibronectin type-IInterPro annotationAdd BLAST43
Domaini559 – 602Fibronectin type-IInterPro annotationAdd BLAST44
Domaini610 – 717Fibronectin type-IIIInterPro annotationAdd BLAST108
Domaini721 – 811Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini812 – 903Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini908 – 997Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini998 – 1087Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini1088 – 1174Fibronectin type-IIIInterPro annotationAdd BLAST87
Domaini1175 – 1265Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini1268 – 1360Fibronectin type-IIIInterPro annotationAdd BLAST93
Domaini1361 – 1448Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini1449 – 1542Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini1543 – 1633Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini1634 – 1723Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini1725 – 1813Fibronectin type-IIIInterPro annotationAdd BLAST89
Domaini1814 – 1904Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini1993 – 2037Fibronectin type-IInterPro annotationAdd BLAST45
Domaini2038 – 2080Fibronectin type-IInterPro annotationAdd BLAST43
Domaini2082 – 2122Fibronectin type-IInterPro annotationAdd BLAST41

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1570 – 1594DisorderedSequence analysisAdd BLAST25

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155126

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00061, FN1, 12 hits
cd00062, FN2, 2 hits
cd00063, FN3, 15 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.10.10.10, 2 hits
2.60.40.10, 15 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000083, Fibronectin_type1
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR000562, FN_type2_dom
IPR036943, FN_type2_sf
IPR013783, Ig-like_fold
IPR013806, Kringle-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00039, fn1, 12 hits
PF00040, fn2, 2 hits
PF00041, fn3, 15 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00058, FN1, 12 hits
SM00059, FN2, 2 hits
SM00060, FN3, 15 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265, SSF49265, 9 hits
SSF57440, SSF57440, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01253, FN1_1, 5 hits
PS51091, FN1_2, 12 hits
PS00023, FN2_1, 1 hit
PS51092, FN2_2, 2 hits
PS50853, FN3, 14 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All

B7ZNJ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRGPGPGRL LLLAVLCLGT SVRCTEAGKS KRQAQQIVQP QSPVAVSQSK
60 70 80 90 100
PGCFDNGKHY QINQQWERTY LGNALVCTCY GGSRGFNCES KPEPEETCFD
110 120 130 140 150
KYTGNTYKVG DTYERPKDSM IWDCTCIGAG RGRISCTIAN RCHEGGQSYK
160 170 180 190 200
IGDKWRRPHE TGGYMLECLC LGNGKGEWTC KPIAEKCFDH AAGTSYVVGE
210 220 230 240 250
TWEKPYQGWM MVDCTCLGEG NGRITCTSRN RCNDQDTRTS YRIGDTWSKK
260 270 280 290 300
DNRGNLLQCV CTGNGRGEWK CERHALQSAS AGSGSFTDVR TAIYQPQTHP
310 320 330 340 350
QPAPYGHCVT DSGVVYSVGM QWLKSQGNKQ MLCTCLGNGV SCQETAVTQT
360 370 380 390 400
YGGNSNGEPC VLPFTYNGRT FYSCTTEGRQ DGHLWCSTTS NYEQDQKYSF
410 420 430 440 450
CTDHAVLVQT RGGNSNGALC HFPFLYNNRN YTDCTSEGRR DNMKWCGTTQ
460 470 480 490 500
NYDADQKFGF CPMAAHEEIC TTNEGVMYRI GDQWDKQHDL GHMMRCTCVG
510 520 530 540 550
NGRGEWACIP YSQLRDQCIV DDITYNVNDT FHKRHEEGHM LNCTCFGQGR
560 570 580 590 600
GRWKCDPIDQ CQDSETRTFY QIGDSWEKFV HGVRYQCYCY GRGIGEWHCQ
610 620 630 640 650
PLQTYPGTTG PVQVIITETP SQPNSHPIQW NAPEPSHITK YILRWRPKTS
660 670 680 690 700
TGRWKEATIP GHLNSYTIKG LTPGVIYEGQ LISIQQYGHR EVTRFDFTTS
710 720 730 740 750
ASTPVTSNTV TGETAPYSPV VATSESVTEI TASSFVVSWV SASDTVSGFR
760 770 780 790 800
VEYELSEEGD EPQYLDLPST ATSVNIPDLL PGRKYIVNVY QISEEGKQSL
810 820 830 840 850
ILSTSQTTAP DAPPDPTVDQ VDDTSIVVRW SRPQAPITGY RIVYSPSVEG
860 870 880 890 900
SSTELNLPET ANSVTLSDLQ PGVQYNITIY AVEENQESTP VFIQQETTGT
910 920 930 940 950
PRSDNVPPPT DLQFVELTDV KVTIMWTPPD SVVSGYRVEV LPVSLPGEHG
960 970 980 990 1000
QRLPVNRNTF AEITGLSPGV TYLFKVFAVH QGRESNPLTA QQTTKLDAPT
1010 1020 1030 1040 1050
NLQFVNETDR TVLVTWTPPR ARIAGYRLTA GLTRGGQPKQ YNVGPLASKY
1060 1070 1080 1090 1100
PLRNLQPGSE YTVTLVAVKG NQQSPKATGV FTTLQPLRSI PPYNTEVTET
1110 1120 1130 1140 1150
TIVITWTPAP RIGFKLGVRP SQGGEAPREV TSDSGSIVVS GLTPGVEYTY
1160 1170 1180 1190 1200
TIQVLRDGQE RDAPIVNRVV TPLSPPTNLH LEANPDTGVL TVSWERSTTP
1210 1220 1230 1240 1250
DITGYRITTT PTNGQQGTSL EEVVHADQSS CTFENLNPGL EYNVSVYTVK
1260 1270 1280 1290 1300
DDKESAPISD TVVPAVPPPT DLRFTNIGPD TMRVTWAPPP SIELTNLLVR
1310 1320 1330 1340 1350
YSPVKNEEDV AELSISPSDN AVVLTNLLPG TEYLVSVSSV YEQHESIPLR
1360 1370 1380 1390 1400
GRQKTGLDSP TGFDSSDITA NSFTVHWVAP RAPITGYIIR HHAEHSVGRP
1410 1420 1430 1440 1450
RQDRVPPSRN SITLTNLNPG TEYVVSIIAV NGREESPPLI GQQATVSDIP
1460 1470 1480 1490 1500
RDLEVIASTP TSLLISWEPP AVSVRYYRIT YGETGGNSPV QEFTVPGSKS
1510 1520 1530 1540 1550
TATINNIKPG ADYTITLYAV TGRGDSPASS KPVSINYKTE IDKPSQMQVT
1560 1570 1580 1590 1600
DVQDNSISVR WLPSTSPVTG YRVTTTPKNG LGPSKTKTAS PDQTEMTIEG
1610 1620 1630 1640 1650
LQPTVEYVVS VYAQNRNGES QPLVQTAVTT IPAPTNLKFS QVTPTSFTAQ
1660 1670 1680 1690 1700
WIAPSVQLTG YRVRVNPKEK TGPMKEINLS PDSSSVIVSG LMVATKYEVS
1710 1720 1730 1740 1750
VYALKDTLTS RPAQGVITTL ENVSPPRRAR VTDATETTIT ISWRTKTETI
1760 1770 1780 1790 1800
TGFQVDAIPA NGQTPVQRSI SPDVRSYTIT GLQPGTDYKI HLYTLNDNAR
1810 1820 1830 1840 1850
SSPVIIDAST AIDAPSNLRF LTTTPNSLLV SWQAPRARIT GYIIKYEKPG
1860 1870 1880 1890 1900
SPPREVVPRP RPGVTEATIT GLEPGTEYTI YVIALKNNQK SEPLIGRKKT
1910 1920 1930 1940 1950
GQEALSQTTI SWTPFQESSE YIISCQPVGT DEEPLQFQVP GTSTSATLTG
1960 1970 1980 1990 2000
LTRGVTYNII VEALQNQRRH KVREEVVTVG NAVSEGLNQP TDDSCFDPYT
2010 2020 2030 2040 2050
VSHYAIGEEW ERLSDAGFKL TCQCLGFGSG HFRCDSSKWC HDNGVNYKIG
2060 2070 2080 2090 2100
EKWDRQGENG QRMSCTCLGN GKGEFKCDPH EATCYDDGKT YHVGEQWQKE
2110 2120 2130 2140 2150
YLGAICSCTC FGGQRGWRCD NCRRPGAAEP SPDGTTGHTY NQYTQRYNQR
2160 2170
TNTNVNCPIE CFMPLDVQAD RDDSRE
Length:2,176
Mass (Da):239,722
Last modified:March 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i52F249E729B49DED
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P11276FINC_MOUSE
Fibronectin
Fn1
2,477Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WS56A0A087WS56_MOUSE
Fibronectin
Fn1
2,266Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B9EHT6B9EHT6_MOUSE
Fibronectin
Fn1
2,271Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q3UHL6Q3UHL6_MOUSE
Fibronectin
Fn1
2,361Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WR50A0A087WR50_MOUSE
Fibronectin
Fn1
2,386Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WSN6A0A087WSN6_MOUSE
Fibronectin
Fn1
2,296Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q4KL80Q4KL80_MOUSE
Fibronectin
Fn1
383Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WQW8A0A087WQW8_MOUSE
Fibronectin
Fn1
160Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WQE0A0A087WQE0_MOUSE
Fibronectin
Fn1
71Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WS99A0A087WS99_MOUSE
Fibronectin
Fn1
200Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There is more potential isoformShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC145271 mRNA Translation: AAI45272.1

NCBI Reference Sequences

More...
RefSeqi
NP_001263342.1, NM_001276413.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000189821; ENSMUSP00000139702; ENSMUSG00000026193

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
14268

UCSC genome browser

More...
UCSCi
uc007bka.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC145271 mRNA Translation: AAI45272.1
RefSeqiNP_001263342.1, NM_001276413.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

ProteomicsDBi328850

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
3522, 2727 antibodies

The DNASU plasmid repository

More...
DNASUi
14268

Genome annotation databases

EnsembliENSMUST00000189821; ENSMUSP00000139702; ENSMUSG00000026193
GeneIDi14268
UCSCiuc007bka.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2335
MGIiMGI:95566, Fn1

Phylogenomic databases

GeneTreeiENSGT00940000155126

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
14268, 1 hit in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Fn1, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000026193, Expressed in vault of skull and 334 other tissues

Family and domain databases

CDDicd00061, FN1, 12 hits
cd00062, FN2, 2 hits
cd00063, FN3, 15 hits
Gene3Di2.10.10.10, 2 hits
2.60.40.10, 15 hits
InterProiView protein in InterPro
IPR000083, Fibronectin_type1
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR000562, FN_type2_dom
IPR036943, FN_type2_sf
IPR013783, Ig-like_fold
IPR013806, Kringle-like
PfamiView protein in Pfam
PF00039, fn1, 12 hits
PF00040, fn2, 2 hits
PF00041, fn3, 15 hits
SMARTiView protein in SMART
SM00058, FN1, 12 hits
SM00059, FN2, 2 hits
SM00060, FN3, 15 hits
SUPFAMiSSF49265, SSF49265, 9 hits
SSF57440, SSF57440, 2 hits
PROSITEiView protein in PROSITE
PS01253, FN1_1, 5 hits
PS51091, FN1_2, 12 hits
PS00023, FN2_1, 1 hit
PS51092, FN2_2, 2 hits
PS50853, FN3, 14 hits

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB7ZNJ1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B7ZNJ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 2, 2021
This is version 95 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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