UniProtKB - B7ZC38 (B7ZC38_HUMAN)
Protein
Submitted name:
Endophilin-B2
Gene
SH3GLB2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Endophilin-B2Imported |
Gene namesi | Name:SH3GLB2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:10834, SH3GLB2 |
VEuPathDBi | HostDB:ENSG00000148341.17 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Nucleus
- nucleoplasm Source: HPA
PTM / Processingi
Proteomic databases
MaxQBi | B7ZC38 |
PeptideAtlasi | B7ZC38 |
PRIDEi | B7ZC38 |
ProteomicsDBi | 7173 |
Expressioni
Gene expression databases
Bgeei | ENSG00000148341, Expressed in pituitary gland and 221 other tissues |
ExpressionAtlasi | B7ZC38, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 24 – 287 | BARInterPro annotationAdd BLAST | 264 | |
Domaini | 340 – 400 | SH3InterPro annotationAdd BLAST | 61 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 207 – 234 | Sequence analysisAdd BLAST | 28 |
Keywords - Domaini
Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000155841 |
OrthoDBi | 803053at2759 |
Family and domain databases
CDDi | cd11944, SH3_Endophilin_B2, 1 hit |
InterProi | View protein in InterPro IPR027267, AH/BAR_dom_sf IPR004148, BAR_dom IPR035640, Endophilin_B2_SH3 IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
Pfami | View protein in Pfam PF03114, BAR, 1 hit PF14604, SH3_9, 1 hit |
SMARTi | View protein in SMART SM00721, BAR, 1 hit SM00326, SH3, 1 hit |
SUPFAMi | SSF103657, SSF103657, 1 hit SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS51021, BAR, 1 hit PS50002, SH3, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
B7ZC38-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDFNMKKLAS DAGIFFTRAV QFTEEKFGQA EKTELDAHFE NLLARADSTK
60 70 80 90 100
NWTEKILRQT EVLLQPNPSA RVEEFLYEKL DRKVPSRVTN GELLAQYMAD
110 120 130 140 150
AASELGPTTP YGKTLIKVAE AEKQLGAAER DFIHTASISF LTPLRNFLEG
160 170 180 190 200
DWKTISKERR LLQNRRLDLD ACKARLKKAK AAEAKATTVP DFQETRPRNY
210 220 230 240 250
ILSASASALW NDEVDKAEQE LRVAQTEFDR QAEVTRLLLE GISSTHVNHL
260 270 280 290 300
RCLHEFVKSQ TTYYAQCYRH MLDLQKQLGS SQGAIFPGTF VGTTEPASPP
310 320 330 340 350
LSSTSPTTAA ATMPVVPSVA SLAPPGEASL CLEEVAPPAS GTRKARVLYD
360 370 380 390 400
YEAADSSELA LLADELITVY SLPGMDPDWL IGERGNKKGK VPVTYLELLS
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9NR46 | SHLB2_HUMAN | Endophilin-B2 | SH3GLB2 KIAA1848, PP578 | 395 | Annotation score: | ||
B7ZC39 | B7ZC39_HUMAN | Endophilin-B2 | SH3GLB2 | 374 | Annotation score: | ||
F8WFB9 | F8WFB9_HUMAN | Endophilin-B2 | SH3GLB2 | 127 | Annotation score: | ||
H7C1Z6 | H7C1Z6_HUMAN | Endophilin-B2 | SH3GLB2 | 59 | Annotation score: | ||
G5E9J1 | G5E9J1_HUMAN | Endophilin-B2 | SH3GLB2 hCG_30604 | 24 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL592211 Genomic DNA No translation available. |
RefSeqi | XP_005252155.1, XM_005252098.2 |
Genome annotation databases
Ensembli | ENST00000417224; ENSP00000402566; ENSG00000148341 |
GeneIDi | 56904 |
UCSCi | uc064wih.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL592211 Genomic DNA No translation available. |
RefSeqi | XP_005252155.1, XM_005252098.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | B7ZC38 |
PeptideAtlasi | B7ZC38 |
PRIDEi | B7ZC38 |
ProteomicsDBi | 7173 |
Protocols and materials databases
Antibodypediai | 17774, 130 antibodies |
Genome annotation databases
Ensembli | ENST00000417224; ENSP00000402566; ENSG00000148341 |
GeneIDi | 56904 |
UCSCi | uc064wih.1, human |
Organism-specific databases
CTDi | 56904 |
HGNCi | HGNC:10834, SH3GLB2 |
OpenTargetsi | ENSG00000148341 |
VEuPathDBi | HostDB:ENSG00000148341.17 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155841 |
OrthoDBi | 803053at2759 |
Miscellaneous databases
BioGRID-ORCSi | 56904, 1 hit in 878 CRISPR screens |
ChiTaRSi | SH3GLB2, human |
GenomeRNAii | 56904 |
Gene expression databases
Bgeei | ENSG00000148341, Expressed in pituitary gland and 221 other tissues |
ExpressionAtlasi | B7ZC38, baseline and differential |
Family and domain databases
CDDi | cd11944, SH3_Endophilin_B2, 1 hit |
InterProi | View protein in InterPro IPR027267, AH/BAR_dom_sf IPR004148, BAR_dom IPR035640, Endophilin_B2_SH3 IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
Pfami | View protein in Pfam PF03114, BAR, 1 hit PF14604, SH3_9, 1 hit |
SMARTi | View protein in SMART SM00721, BAR, 1 hit SM00326, SH3, 1 hit |
SUPFAMi | SSF103657, SSF103657, 1 hit SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS51021, BAR, 1 hit PS50002, SH3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B7ZC38_HUMAN | |
Accessioni | B7ZC38Primary (citable) accession number: B7ZC38 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 3, 2009 |
Last sequence update: | March 3, 2009 | |
Last modified: | February 10, 2021 | |
This is version 93 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |