UniProtKB - B7ZA03 (B7ZA03_HUMAN)
Protein
Submitted name:
cDNA, FLJ79017, highly similar to Tyrosine-protein phosphatase non-receptor type3
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- protein tyrosine phosphatase activity Source: InterPro
Keywordsi
Molecular function | ReceptorImported |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA, FLJ79017, highly similar to Tyrosine-protein phosphatase non-receptor type3Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 178 – 250 | PDZInterPro annotationAdd BLAST | 73 | |
Domaini | 314 – 569 | Tyrosine-protein phosphataseInterPro annotationAdd BLAST | 256 | |
Domaini | 487 – 560 | TYR_PHOSPHATASE_2InterPro annotationAdd BLAST | 74 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 41 – 64 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 91 – 143 | DisorderedSequence analysisAdd BLAST | 53 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 91 – 138 | PolarSequence analysisAdd BLAST | 48 |
Phylogenomic databases
OrthoDBi | 96595at2759 |
Family and domain databases
Gene3Di | 2.30.29.30, 1 hit 2.30.42.10, 1 hit 3.90.190.10, 1 hit |
InterProi | View protein in InterPro IPR001478, PDZ IPR036034, PDZ_sf IPR011993, PH-like_dom_sf IPR029021, Prot-tyrosine_phosphatase-like IPR000242, PTPase_domain IPR016130, Tyr_Pase_AS IPR003595, Tyr_Pase_cat IPR000387, TYR_PHOSPHATASE_dom |
Pfami | View protein in Pfam PF00595, PDZ, 1 hit PF00102, Y_phosphatase, 1 hit |
PRINTSi | PR00700, PRTYPHPHTASE |
SMARTi | View protein in SMART SM00228, PDZ, 1 hit SM00194, PTPc, 1 hit SM00404, PTPc_motif, 1 hit |
SUPFAMi | SSF50156, SSF50156, 1 hit SSF52799, SSF52799, 1 hit |
PROSITEi | View protein in PROSITE PS50106, PDZ, 1 hit PS00383, TYR_PHOSPHATASE_1, 1 hit PS50056, TYR_PHOSPHATASE_2, 1 hit PS50055, TYR_PHOSPHATASE_PTP, 1 hit |
i Sequence
Sequence statusi: Complete.
B7ZA03-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLNYRSCKNL WKSCVEHHTF FQAKKLLPQE KNVLSQYWTM GSRNTKKRSP
60 70 80 90 100
RLRHEIRKPR HSSADNLANE MTYITETEDV FYTYKGSLAP QDSDSEVSQN
110 120 130 140 150
RSPHQESLSE NNPAQSYLTQ KSSSSVSPSS NAPGSCSPDG VDQQLLDDFH
160 170 180 190 200
RVTKGGSTED ASQYYCDKND NGDSYLVLIR ITPDEDGKFG FNLKGGVDQK
210 220 230 240 250
MPLVVSRINP ESPADTCIPK LNEGDQIVLI NGRDISEHTH DQVVMFIKAS
260 270 280 290 300
RESHSRELAL VIRRRAVRSF ADFKSEDELN QLFPEAIFPM CPEGGDTLEG
310 320 330 340 350
SMAQLKKGLE SGTVLIQFEQ LYRKKPGLAI TFAKLPQNLD KNRYKDVLPY
360 370 380 390 400
DTTRVLLQGN EDYINASYVN MEIPAANLVN EYIATQGPLP HTCAQFWQVV
410 420 430 440 450
WDQKLSLIVM LTTLTERGRT KCHQYWPDPP DVMNHGGFHI QCQSEDCTIA
460 470 480 490 500
YVSREMLVTN TQTGEEHTVT HLQYVAWPDH GVPDDSSDFL EFVNYVRSLR
510 520 530 540 550
VDSEPVLVHC SAGIGRTGVL VTMETAMCLT ERNLPIYPLD IVRKMRDQRA
560 570 580
MMVQTSSQYK FVCEAILRVY EEGLVQMLDP S
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK316118 mRNA Translation: BAH14489.1 |
RefSeqi | NP_001138844.1, NM_001145372.1 |
Genome annotation databases
GeneIDi | 5774 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK316118 mRNA Translation: BAH14489.1 |
RefSeqi | NP_001138844.1, NM_001145372.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | B7ZA03 |
Protocols and materials databases
DNASUi | 5774 |
Genome annotation databases
GeneIDi | 5774 |
Organism-specific databases
CTDi | 5774 |
PharmGKBi | PA33999 |
Phylogenomic databases
OrthoDBi | 96595at2759 |
Miscellaneous databases
BioGRID-ORCSi | 5774, 3 hits in 872 CRISPR screens |
GenomeRNAii | 5774 |
Gene expression databases
Genevisiblei | B7ZA03, HS |
Family and domain databases
Gene3Di | 2.30.29.30, 1 hit 2.30.42.10, 1 hit 3.90.190.10, 1 hit |
InterProi | View protein in InterPro IPR001478, PDZ IPR036034, PDZ_sf IPR011993, PH-like_dom_sf IPR029021, Prot-tyrosine_phosphatase-like IPR000242, PTPase_domain IPR016130, Tyr_Pase_AS IPR003595, Tyr_Pase_cat IPR000387, TYR_PHOSPHATASE_dom |
Pfami | View protein in Pfam PF00595, PDZ, 1 hit PF00102, Y_phosphatase, 1 hit |
PRINTSi | PR00700, PRTYPHPHTASE |
SMARTi | View protein in SMART SM00228, PDZ, 1 hit SM00194, PTPc, 1 hit SM00404, PTPc_motif, 1 hit |
SUPFAMi | SSF50156, SSF50156, 1 hit SSF52799, SSF52799, 1 hit |
PROSITEi | View protein in PROSITE PS50106, PDZ, 1 hit PS00383, TYR_PHOSPHATASE_1, 1 hit PS50056, TYR_PHOSPHATASE_2, 1 hit PS50055, TYR_PHOSPHATASE_PTP, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B7ZA03_HUMAN | |
Accessioni | B7ZA03Primary (citable) accession number: B7ZA03 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 3, 2009 |
Last sequence update: | March 3, 2009 | |
Last modified: | February 10, 2021 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |