UniProtKB - B7Z8L1 (B7Z8L1_HUMAN)
Protein
Submitted name:
Periphilin-1
Gene
PPHLN1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- negative regulation of transcription, DNA-templated Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Periphilin-1ImportedSubmitted name: cDNA FLJ52823, highly similar to Periphilin-1Imported |
Gene namesi | Name:PPHLN1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:19369, PPHLN1 |
VEuPathDBi | HostDB:ENSG00000134283.17 |
Expressioni
Gene expression databases
Bgeei | ENSG00000134283, Expressed in testis and 221 other tissues |
ExpressionAtlasi | B7Z8L1, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 229 | DisorderedSequence analysisAdd BLAST | 229 | |
Regioni | 290 – 318 | DisorderedSequence analysisAdd BLAST | 29 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 84 | PolyampholyteSequence analysisAdd BLAST | 84 | |
Compositional biasi | 85 – 118 | PolarSequence analysisAdd BLAST | 34 | |
Compositional biasi | 128 – 143 | PolyampholyteSequence analysisAdd BLAST | 16 | |
Compositional biasi | 144 – 164 | PolarSequence analysisAdd BLAST | 21 | |
Compositional biasi | 165 – 195 | PolyampholyteSequence analysisAdd BLAST | 31 | |
Compositional biasi | 211 – 229 | PolarSequence analysisAdd BLAST | 19 |
Phylogenomic databases
GeneTreei | ENSGT00390000016228 |
OrthoDBi | 924482at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR028851, Pphln1 |
PANTHERi | PTHR15836, PTHR15836, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All
B7Z8L1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MWSEGRYEYE RIPRERAPPR SHPSDESGYR WTRDDHSASR QPEYRDMRDG
60 70 80 90 100
FRRKSFYSSH YARERSPYKR DNTFFRESPV GRKDSPHSRS GSSVSSRSYS
110 120 130 140 150
PERSKSYSFH QSQHRKSVRP GASYKRQNEG NPERDKERPV QSLKTSRDTS
160 170 180 190 200
PSSGSAVSSS KVLDKPSRLT EKELAEAASK WAAEKLEKSD ESNLPEISEY
210 220 230 240 250
EAGSTAPLFT DQPEEPESNT THGIELFEDS QLTTRSKAIA SKTKEIEQVY
260 270 280 290 300
RQDCETFGMV VKMLIEKDPS LEKSIQFALR QNLHEIESAG QTWQQVPPVR
310 320 330 340
NTEMDHDGTP ENEGEETAQS NLETALIKST LEPALCAFFL
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8NEY8 | PPHLN_HUMAN | Periphilin-1 | PPHLN1 HSPC206, HSPC232 | 458 | Annotation score: | ||
F8W0Q9 | F8W0Q9_HUMAN | Periphilin-1 | PPHLN1 | 385 | Annotation score: | ||
F8WF16 | F8WF16_HUMAN | Periphilin-1 | PPHLN1 | 303 | Annotation score: | ||
F8VWU8 | F8VWU8_HUMAN | Periphilin-1 | PPHLN1 | 168 | Annotation score: | ||
F8W6A0 | F8W6A0_HUMAN | Periphilin-1 | PPHLN1 | 363 | Annotation score: | ||
F8VPY7 | F8VPY7_HUMAN | Periphilin-1 | PPHLN1 | 161 | Annotation score: | ||
F8VRK2 | F8VRK2_HUMAN | Periphilin-1 | PPHLN1 | 107 | Annotation score: | ||
F8VP48 | F8VP48_HUMAN | Periphilin-1 | PPHLN1 | 52 | Annotation score: | ||
F8VXV7 | F8VXV7_HUMAN | Periphilin-1 | PPHLN1 | 37 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC020629 Genomic DNA No translation available. AC079601 Genomic DNA No translation available. AC079684 Genomic DNA No translation available. AK303612 mRNA Translation: BAH13997.1 |
Genome annotation databases
Ensembli | ENST00000337898; ENSP00000338510; ENSG00000134283 |
UCSCi | uc010skr.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC020629 Genomic DNA No translation available. AC079601 Genomic DNA No translation available. AC079684 Genomic DNA No translation available. AK303612 mRNA Translation: BAH13997.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | B7Z8L1 |
PRIDEi | B7Z8L1 |
Protocols and materials databases
Antibodypediai | 25050, 153 antibodies |
Genome annotation databases
Ensembli | ENST00000337898; ENSP00000338510; ENSG00000134283 |
UCSCi | uc010skr.2, human |
Organism-specific databases
HGNCi | HGNC:19369, PPHLN1 |
OpenTargetsi | ENSG00000134283 |
VEuPathDBi | HostDB:ENSG00000134283.17 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000016228 |
OrthoDBi | 924482at2759 |
Miscellaneous databases
ChiTaRSi | PPHLN1, human |
Gene expression databases
Bgeei | ENSG00000134283, Expressed in testis and 221 other tissues |
ExpressionAtlasi | B7Z8L1, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR028851, Pphln1 |
PANTHERi | PTHR15836, PTHR15836, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B7Z8L1_HUMAN | |
Accessioni | B7Z8L1Primary (citable) accession number: B7Z8L1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 3, 2009 |
Last sequence update: | March 3, 2009 | |
Last modified: | April 7, 2021 | |
This is version 92 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |