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Entry version 68 (16 Jan 2019)
Sequence version 1 (03 Mar 2009)
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Protein
Submitted name:

cDNA FLJ56258, highly similar to Squamous cell carcinoma antigen recognized by T-cells 2

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
cDNA FLJ56258, highly similar to Squamous cell carcinoma antigen recognized by T-cells 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei922 – 941HelicalSequence analysisAdd BLAST20
Transmembranei953 – 970HelicalSequence analysisAdd BLAST18

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

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MaxQBi
B7Z765

PeptideAtlas

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PeptideAtlasi
B7Z765

PRoteomics IDEntifications database

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PRIDEi
B7Z765

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
B7Z765

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini167 – 336DUF4962InterPro annotationAdd BLAST170

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IKEY Eukaryota
ENOG410ZW1M LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000072706

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG057715

Database of Orthologous Groups

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OrthoDBi
588663at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
B7Z765

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.50.10.100, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR008929 Chondroitin_lyas
IPR032518 HepII_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16332 DUF4962, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF48230 SSF48230, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B7Z765-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSFEDGLAA LEIWRSDATM RTHTRGAPSV FFIYLLCFVS AYITDENPEV
60 70 80 90 100
MIPFTNANYD SHPMLYFSRA EVAELQLRAA SSHEHIAARL TEAVHTMLSS
110 120 130 140 150
PLEYLPPWDP KDYSARWNEI FGNNLGALAM FCVLYPENIE ARDMAKDYME
160 170 180 190 200
RMAAQPSWLV KDAPWDEVPL AHSLVGFATA YDFLYNYLSK TQQEKFLEVI
210 220 230 240 250
ANASGYMYET SYRRGWGFQY LHNHQPTNCM ALLTGSLVLM NQGYLQEAYL
260 270 280 290 300
WTKQVLTIME KSLVLLREVT DGSLYEGVAY GSYTTRSLFQ YMFLVQRHFN
310 320 330 340 350
INHFGHPWLK QHFAFMYRTI LPGFQRTVAI ADSNYNWFYG PESQLVFLDK
360 370 380 390 400
FVMRNGSGNW LADQIRRNRV VEGPGTPSKG QRWCTLHTEF LWYDGSLKSV
410 420 430 440 450
PPPDFGTPTL HYFEDWGVVT YGSALPAEIN RSFLSFKSGK LGGRAIYDIV
460 470 480 490 500
HRNKYKDWIK GWRNFNAGHE HPDQNSFTFA PNGVPFITEA LYGPKYTFFN
510 520 530 540 550
NVLMFSPAVS KSCFSPWVGQ VTEDCSSKWS KYKHDLAASC QGRVVAAEEK
560 570 580 590 600
NGVVFIRGEG VGAYNPQLNL KNVQRNLILL HPQLLLLVDQ IHLGEESPLE
610 620 630 640 650
TAASFFHNVD VPFEETVVDG VHGAFIRQRD GLYKMYWMDD TGYSEKATFA
660 670 680 690 700
SVTYPRGYPY NGTNYVNVTM HLRSPITRAA YLFIGPSIDV QSFTVHGDSQ
710 720 730 740 750
QLDVFIATSK HAYATYLWTG EATGQSAFAQ VIADRHKILF DRNSAIKSSI
760 770 780 790 800
VPEVKDYAAI VEQNLQHFKP VFQLLEKQIL SRVRNTASFR KTAERLLRFS
810 820 830 840 850
DKRQTEEAID RIFAISQQQQ QQSKSKKNRR AGKRYKFVDA VPDIFAQIEV
860 870 880 890 900
NEKKIRQKAQ ILAQKELPID EDEEMKDLLD FADVTYEKHK NGGLIKGRFG
910 920 930 940 950
QARMVTTTHS RAPSLSASYT RLFLILNIAI FFVMLAMQLT YFQRAQSLHG
960 970
QRCLYAVLLI DSCILLWLYS SCSQSQC
Length:977
Mass (Da):111,824
Last modified:March 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA036EF317419C504
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AK301513 mRNA Translation: BAH13501.1

NCBI Reference Sequences

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RefSeqi
NP_001309868.1, NM_001322939.1
XP_016866284.1, XM_017010795.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.458358
Hs.547713

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
29940

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK301513 mRNA Translation: BAH13501.1
RefSeqiNP_001309868.1, NM_001322939.1
XP_016866284.1, XM_017010795.1
UniGeneiHs.458358
Hs.547713

3D structure databases

ProteinModelPortaliB7Z765
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB7Z765
PeptideAtlasiB7Z765
PRIDEiB7Z765

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi29940

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
29940

Phylogenomic databases

eggNOGiENOG410IKEY Eukaryota
ENOG410ZW1M LUCA
HOGENOMiHOG000072706
HOVERGENiHBG057715
OrthoDBi588663at2759
PhylomeDBiB7Z765

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
29940

Family and domain databases

Gene3Di1.50.10.100, 1 hit
InterProiView protein in InterPro
IPR008929 Chondroitin_lyas
IPR032518 HepII_N
PfamiView protein in Pfam
PF16332 DUF4962, 1 hit
SUPFAMiSSF48230 SSF48230, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB7Z765_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B7Z765
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: January 16, 2019
This is version 68 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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