UniProtKB - B7Z6U3 (B7Z6U3_HUMAN)
Protein
Submitted name:
Lysosomal acid phosphatase
Gene
ACP2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Lysosomal acid phosphataseImportedSubmitted name: cDNA FLJ51107, highly similar to Lysosomal acid phosphataseImported |
Gene namesi | Name:ACP2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000134575.9 |
HGNCi | HGNC:123, ACP2 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 30 | Sequence analysisAdd BLAST | 30 | |
ChainiPRO_5014085667 | 31 – 162 | Sequence analysisAdd BLAST | 132 |
Proteomic databases
MaxQBi | B7Z6U3 |
PRIDEi | B7Z6U3 |
ProteomicsDBi | 6806 |
Expressioni
Gene expression databases
Bgeei | ENSG00000134575, Expressed in right lobe of liver and 232 other tissues |
ExpressionAtlasi | B7Z6U3, baseline and differential |
Family & Domainsi
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000158446 |
Family and domain databases
CDDi | cd07061, HP_HAP_like, 1 hit |
Gene3Di | 3.40.50.1240, 1 hit |
InterProi | View protein in InterPro IPR033379, Acid_Pase_AS IPR000560, His_Pase_clade-2 IPR029033, His_PPase_superfam |
Pfami | View protein in Pfam PF00328, His_Phos_2, 1 hit |
SUPFAMi | SSF53254, SSF53254, 1 hit |
PROSITEi | View protein in PROSITE PS00616, HIS_ACID_PHOSPHAT_1, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All
B7Z6U3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGKRSGWSR AALLQLLLGV NLVVMPPTRA RSLRFVTLLY RHGDRSPVKT
60 70 80 90 100
YPKDPYQEEE WPQGFGQLTK EGMLQHWELG QALRQRYHGF LNTSYHRQEV
110 120 130 140 150
YVRSTDFDRT LMSAEANLAG LFPPNGMQRF NPNISWQPIP VHTVPITEDR
160
QAQVTRTVEH SA
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP11117 | PPAL_HUMAN | Lysosomal acid phosphatase | ACP2 | 423 | Annotation score: | ||
A0A5F9ZHR7 | A0A5F9ZHR7_HUMAN | Lysosomal acid phosphatase | ACP2 | 434 | Annotation score: | ||
E9PHY0 | E9PHY0_HUMAN | Lysosomal acid phosphatase | ACP2 | 360 | Annotation score: | ||
B7Z7D2 | B7Z7D2_HUMAN | Lysosomal acid phosphatase | ACP2 | 391 | Annotation score: | ||
E9PQY3 | E9PQY3_HUMAN | Lysosomal acid phosphatase | ACP2 | 395 | Annotation score: | ||
A0A5F9ZH40 | A0A5F9ZH40_HUMAN | Lysosomal acid phosphatase | ACP2 | 160 | Annotation score: | ||
A0A5F9ZH82 | A0A5F9ZH82_HUMAN | Lysosomal acid phosphatase | ACP2 | 305 | Annotation score: | ||
A0A5F9ZI20 | A0A5F9ZI20_HUMAN | Lysosomal acid phosphatase | ACP2 | 151 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC018410 Genomic DNA No translation available. AK300931 mRNA Translation: BAH13379.1 |
Genome annotation databases
Ensembli | ENST00000672787; ENSP00000500408; ENSG00000134575 |
UCSCi | uc058bce.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC018410 Genomic DNA No translation available. AK300931 mRNA Translation: BAH13379.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | B7Z6U3 |
PRIDEi | B7Z6U3 |
ProteomicsDBi | 6806 |
Protocols and materials databases
Antibodypediai | 26620, 103 antibodies |
Genome annotation databases
Ensembli | ENST00000672787; ENSP00000500408; ENSG00000134575 |
UCSCi | uc058bce.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000134575.9 |
HGNCi | HGNC:123, ACP2 |
NIAGADSi | ENSG00000134575 |
OpenTargetsi | ENSG00000134575 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158446 |
Miscellaneous databases
ChiTaRSi | ACP2, human |
Gene expression databases
Bgeei | ENSG00000134575, Expressed in right lobe of liver and 232 other tissues |
ExpressionAtlasi | B7Z6U3, baseline and differential |
Family and domain databases
CDDi | cd07061, HP_HAP_like, 1 hit |
Gene3Di | 3.40.50.1240, 1 hit |
InterProi | View protein in InterPro IPR033379, Acid_Pase_AS IPR000560, His_Pase_clade-2 IPR029033, His_PPase_superfam |
Pfami | View protein in Pfam PF00328, His_Phos_2, 1 hit |
SUPFAMi | SSF53254, SSF53254, 1 hit |
PROSITEi | View protein in PROSITE PS00616, HIS_ACID_PHOSPHAT_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B7Z6U3_HUMAN | |
Accessioni | B7Z6U3Primary (citable) accession number: B7Z6U3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 3, 2009 |
Last sequence update: | March 3, 2009 | |
Last modified: | August 12, 2020 | |
This is version 83 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |