UniProtKB - B7Z6E8 (B7Z6E8_HUMAN)
Protein
Submitted name:
cDNA FLJ59425, highly similar to SH3-domain kinase-binding protein 1
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- kinase activity Source: UniProtKB-KW
Keywordsi
Molecular function | KinaseImported, Transferase |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA FLJ59425, highly similar to SH3-domain kinase-binding protein 1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- cytoplasm Source: UniProtKB-KW
- focal adhesion Source: UniProtKB-SubCell
- membrane Source: UniProtKB-KW
PTM / Processingi
Proteomic databases
MaxQBi | B7Z6E8 |
PeptideAtlasi | B7Z6E8 |
PRIDEi | B7Z6E8 |
ProteomicsDBi | 6774 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 67 | SH3InterPro annotationAdd BLAST | 62 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 67 – 183 | DisorderedSequence analysisAdd BLAST | 117 | |
Regioni | 206 – 349 | DisorderedSequence analysisAdd BLAST | 144 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 92 – 129 | PolyampholyteSequence analysisAdd BLAST | 38 | |
Compositional biasi | 209 – 246 | PolarSequence analysisAdd BLAST | 38 | |
Compositional biasi | 248 – 270 | PolyampholyteSequence analysisAdd BLAST | 23 | |
Compositional biasi | 271 – 287 | PolarSequence analysisAdd BLAST | 17 | |
Compositional biasi | 308 – 326 | PolarSequence analysisAdd BLAST | 19 |
Keywords - Domaini
SH3 domainPROSITE-ProRule annotationARBA annotationPhylogenomic databases
OrthoDBi | 1577081at2759 |
Family and domain databases
CDDi | cd12057, SH3_CIN85_3, 1 hit |
InterProi | View protein in InterPro IPR028445, CD2AP IPR035772, CIN85_SH3_3 IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR14167:SF23, PTHR14167:SF23, 1 hit |
Pfami | View protein in Pfam PF14604, SH3_9, 1 hit |
PRINTSi | PR00452, SH3DOMAIN |
SMARTi | View protein in SMART SM00326, SH3, 1 hit |
SUPFAMi | SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS50002, SH3, 1 hit |
i Sequence
Sequence statusi: Complete.
B7Z6E8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDSRTKSKDY CKVIFPYEAQ NDDELTIKEG DIVTLINKDC IDVGWWEGEL
60 70 80 90 100
NGRRGVFPDN FVKLLPPDFE KEGNRPKKPP PPSAPVIKQG AGTTERKHEI
110 120 130 140 150
KKIPPERPEM LPNRTEEKER PEREPKLDLQ KPSVPAIPPK KPRPPKTNSL
160 170 180 190 200
SRPGALPPRR PERPVGPLTH TRGDSPKIDL AGSSLSGILD KDLSDRSNDI
210 220 230 240 250
DLEGFDSVVS STEKLSHPTT SRPKATGRRP PSQSLTSSSL SSPDIFDSPS
260 270 280 290 300
PEEDKEEHIS LAHRGVDASK KTSKTVTISQ VSDNKASLPP KPGTMAAGGG
310 320 330 340 350
GPAPLSSAAP SPLSSSLGTA GHRANSPSLF GTEGKPKMEP AASSQAAVEE
360 370 380 390 400
LRTQVRELRS IIETMKDQQK REIKQLLSEL DEEKKIRLRL QMEVNDIKKA
LQSK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK300189 mRNA Translation: BAH13234.1 |
RefSeqi | XP_016884958.1, XM_017029469.1 |
Genome annotation databases
GeneIDi | 30011 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK300189 mRNA Translation: BAH13234.1 |
RefSeqi | XP_016884958.1, XM_017029469.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | B7Z6E8 |
PeptideAtlasi | B7Z6E8 |
PRIDEi | B7Z6E8 |
ProteomicsDBi | 6774 |
Genome annotation databases
GeneIDi | 30011 |
Organism-specific databases
CTDi | 30011 |
Phylogenomic databases
OrthoDBi | 1577081at2759 |
Miscellaneous databases
BioGRID-ORCSi | 30011, 5 hits in 500 CRISPR screens |
GenomeRNAii | 30011 |
Family and domain databases
CDDi | cd12057, SH3_CIN85_3, 1 hit |
InterProi | View protein in InterPro IPR028445, CD2AP IPR035772, CIN85_SH3_3 IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR14167:SF23, PTHR14167:SF23, 1 hit |
Pfami | View protein in Pfam PF14604, SH3_9, 1 hit |
PRINTSi | PR00452, SH3DOMAIN |
SMARTi | View protein in SMART SM00326, SH3, 1 hit |
SUPFAMi | SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS50002, SH3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B7Z6E8_HUMAN | |
Accessioni | B7Z6E8Primary (citable) accession number: B7Z6E8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 3, 2009 |
Last sequence update: | March 3, 2009 | |
Last modified: | February 10, 2021 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |