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UniProtKB - B7Z5J4 (B7Z5J4_HUMAN)
Protein
Submitted name:
Carboxypeptidase A4
Gene
CPA4
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- metallocarboxypeptidase activity Source: InterPro
- zinc ion binding Source: InterPro
Keywordsi
Molecular function | CarboxypeptidaseImported, Hydrolase, Protease |
Protein family/group databases
MEROPSi | M14.017 |
Names & Taxonomyi
Protein namesi | Submitted name: Carboxypeptidase A4ImportedSubmitted name: cDNA FLJ52025, highly similar to Carboxypeptidase A4Imported |
Gene namesi | Name:CPA4Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:15740, CPA4 |
VEuPathDBi | HostDB:ENSG00000128510 |
Expressioni
Gene expression databases
Bgeei | ENSG00000128510, Expressed in ectocervix and 94 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 68 – 90 | Peptidase_M14InterPro annotationAdd BLAST | 23 | |
Domaini | 204 – 214 | Peptidase_M14InterPro annotationAdd BLAST | 11 |
Sequence similaritiesi
Belongs to the peptidase M14 family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00940000161774 |
HOGENOMi | CLU_019326_0_0_1 |
OMAi | QQNEGQE |
Family and domain databases
CDDi | cd03870, M14_CPA, 1 hit |
InterProi | View protein in InterPro IPR034248, CPA_M14_CPD IPR000834, Peptidase_M14 |
Pfami | View protein in Pfam PF00246, Peptidase_M14, 1 hit |
PRINTSi | PR00765, CRBOXYPTASEA |
SMARTi | View protein in SMART SM00631, Zn_pept, 1 hit |
PROSITEi | View protein in PROSITE PS00132, CARBOXYPEPT_ZN_1, 1 hit PS00133, CARBOXYPEPT_ZN_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
B7Z5J4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQHNEGQERS SNNFNYGAYH SLEAIYHEMD NIAADFPDLA RRVKIGHSFE
60 70 80 90 100
NRPMYVLKFS TGKGVRRPAV WLNAGIHSRE WISQATAIWT ARKIVSDYQR
110 120 130 140 150
DPAITSILEK MDIFLLPVAN PDGYVYTQTQ NRLWRKTRSR NPGSSCIGAD
160 170 180 190 200
PNRNWNASFA GKGASDNPCS EVYHGPHANS EVEVKSVVDF IQKHGNFKGF
210 220 230 240 250
IDLHSYSQLL MYPYGYSVKK APDAEELDKV ARLAAKALAS VSGTEYQVGP
260 270 280 290 300
TCTTVYPASG SSIDWAYDNG IKFAFTFELR DTGTYGFLLP ANQIIPTAEE
310
TWLGLKTIME HVRDNLY
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UI42 | CBPA4_HUMAN | Carboxypeptidase A4 | CPA4 CPA3, UNQ694/PRO1339 | 421 | Annotation score: | ||
C9J3P4 | C9J3P4_HUMAN | Carboxypeptidase A4 | CPA4 | 171 | Annotation score: | ||
C9J6N7 | C9J6N7_HUMAN | Carboxypeptidase A4 | CPA4 | 177 | Annotation score: | ||
C9J7D6 | C9J7D6_HUMAN | Carboxypeptidase A4 | CPA4 | 29 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC024085 Genomic DNA No translation available. AK299023 mRNA Translation: BAH12930.1 |
Genome annotation databases
Ensembli | ENST00000493259; ENSP00000419660; ENSG00000128510 |
UCSCi | uc011kpe.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC024085 Genomic DNA No translation available. AK299023 mRNA Translation: BAH12930.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
MEROPSi | M14.017 |
Proteomic databases
ProteomicsDBi | 6697 |
Protocols and materials databases
Antibodypediai | 17950, 89 antibodies from 26 providers |
Genome annotation databases
Ensembli | ENST00000493259; ENSP00000419660; ENSG00000128510 |
UCSCi | uc011kpe.3, human |
Organism-specific databases
HGNCi | HGNC:15740, CPA4 |
OpenTargetsi | ENSG00000128510 |
VEuPathDBi | HostDB:ENSG00000128510 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000161774 |
HOGENOMi | CLU_019326_0_0_1 |
OMAi | QQNEGQE |
Miscellaneous databases
ChiTaRSi | CPA4, human |
Gene expression databases
Bgeei | ENSG00000128510, Expressed in ectocervix and 94 other tissues |
Family and domain databases
CDDi | cd03870, M14_CPA, 1 hit |
InterProi | View protein in InterPro IPR034248, CPA_M14_CPD IPR000834, Peptidase_M14 |
Pfami | View protein in Pfam PF00246, Peptidase_M14, 1 hit |
PRINTSi | PR00765, CRBOXYPTASEA |
SMARTi | View protein in SMART SM00631, Zn_pept, 1 hit |
PROSITEi | View protein in PROSITE PS00132, CARBOXYPEPT_ZN_1, 1 hit PS00133, CARBOXYPEPT_ZN_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | B7Z5J4_HUMAN | |
Accessioni | B7Z5J4Primary (citable) accession number: B7Z5J4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 3, 2009 |
Last sequence update: | March 3, 2009 | |
Last modified: | January 19, 2022 | |
This is version 89 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |